Childhood callous-unemotional traits (CU), defined as a lack of guilt, empathy, and affect, are important in understanding conduct problems and other maladaptive behaviors. Early CU, in particular, has received recent attention, though current conceptualizations often extrapolate from the adult literature and lack a more nuanced developmental perspective. CU, however, may manifest differently earlier in development. The aims of this project were to further our current understanding of the early CU construct by investigating; 1) long-term stability and its underlying genetic and environmental etiology from early childhood to adolescence; 2) structural, developmental, and etiological similarities and distinctions between CU and prosociality; and 3) the extent to which early CU and prosociality differentially predict adolescent outcomes. I hypothesized modest stability and predictive validity of early CU into adolescence, and expected early CU and prosociality to be separate but related constructs. Two longitudinal twin samples were used to address these aims (Sample 1: Ages 2 and 3 years [N=314 twin pairs], followed-up in adolescence M=14.5 years [N=128 twin pairs]; Sample 2: Ages 3, 4, and 5 years [N=310 twin pairs]). Study hypotheses were largely supported. In Study 1 (Sample 1), parent-reported CU was modestly stable, and common genetic factors contributed to this stability. However, most of the genetic and environmental variance was unique to adolescent CU. In Study 2 (Sample 2), confirmatory factor analysis, longitudinal growth modeling, and twin analyses supported early CU and prosociality as distinct but related constructs at the structural, developmental, and etiological level, respectively. Study 3 (Sample 1) further supported distinctions between early CU and low prosociality by demonstrating that both independently predicted adolescent externalizing behavioral outcomes. These studies highlight the long-term developmental significance of early CU, in both its stability and predictive validity into adolescence. Furthermore, this work demonstrates the relevance of prosociality to our understanding of early CU, highlighting the utility of integrating childhood CU research with work on normative prosocial development. That being said, CU and prosociality are not simply flip sides of the same coin in early childhood, and should be viewed as distinct constructs that independently explain maladaptive behavior.

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The presence of callous-unemotional (CU) traits (e.g., shallow affect, lack of empathy) in children predicts reduced prosocial behavior. Similarly, CU traits relate to emotion recognition deficits, which may be related to deficits in visual attention to the eye region of others. Notably, recognition of others' distress necessarily precedes sympathy, and sympathy is a key predictor in prosocial outcomes. Thus, visual attention and emotion recognition may mediate the relationship between CU traits and deficient prosocial behavior. Elucidating these connections furthers the development of treatment protocols for children with behavioral problems and CU traits. This study seeks to: (1) extend this research to younger children, including girls; (2) measure eye gaze using infrared eye-tracking technology; and (3) test the hypothesis that CU traits are linked to prosocial behavior deficits via reduced eye gaze, which in turn leads to deficits in fear recognition. Children (n = 81, ages 6-9) completed a computerized, eye-tracked emotion recognition task and a standardized prosocial behavior task while parents reported on the children's CU traits. Results partially supported hypotheses, in that CU traits predicted less time focusing on the eye region for fear expressions, and certain dimensions of eye gaze predicted accuracy in recognizing some emotions. However, the full model was not supported for fear or distress expressions. Conversely, there was some evidence that the link between CU traits and deficient prosocial behavior is mediated by reduced recognition for low intensity happy expressions, but only in girls. Theoretical and practical implications for these findings are considered. / Master of Science

Research has shown that children displaying conduct problems (CP) early in life are at greater risk for severe CP and other negative outcomes later in life. However, not all children with early-onset CP will develop severe CP over the life-course. Thus, it is important to identify those at greater risk, preferably as early as possible, in order to adequately prevent a negative development. Psychopathic traits have received much attention in research on risk for severe CP, involving attempts to extend these traits, and their association to CP to childhood. However, research has thus far mainly focused on one dimension of psychopathic traits, that is callousunemotional (CU) traits, to some extent neglecting two other dimensions of traits commonly included in a psychopathic personality: an interpersonal, and a behavioural dimension. Hence, we still do not know if a full psychopathic personality is identifiable in early childhood, and if and how it is related to the development of severe and persistent CP. The aim of this dissertation was to examine if a psychopathic personality could be identified in early childhood, if psychopathic traits are stable over time, and if and how the psychopathic personality is related to childhood CP. Overall, the results show that psychopathic traits, as well as the display of a psychopathic personality, could be identified in early childhood. These traits were stable over time, and they were clearly and strongly related to childhood CP. Additionally, the combination of early-onset CP and a full psychopathic personality seems to be the most precarious for severe and persistent CP, even more so than the combination of CP and CU traits. With careful consideration to ethical aspects, these results are discussed both in relation to a developmental psychopathology perspective on CP, as well as in relation to diagnostic practice as it is framed today.

There is a growing body of research suggesting that the presence of psychopathic traits, and more specifically, callous-unemotional traits in youth, may constitute a distinct developmental pathway to aggressive behavior. However, ethnic groups are understudied in this literature such that it is unclear whether the correlates of psychopathic traits (i.e., violence, aggression, emotional processing deficits) are equally associated with these traits across different ethnic groups. Also, most theories on the development of psychopathy have provided biologically-based explanations for the cognitive-affective deficits that are considered to be core features of psychopathy. However, research suggests that exposure to adverse contextual environments is also associated with emotional processing deficits and could be important in the etiology of psychopathic traits. The current study examined callous-unemotional traits, emotional processing using the emotional pictures dot-probe task, and exposure to adverse contextual environments (i.e., community violence, abuse) in sixty African American and twenty Caucasian detained boys (n = 80). The results of the current study revealed that aggression, delinquency, and violence were associated with psychopathic traits and this did not differ across ethnic groups. Also, there was an interaction between psychopathic traits and aggression that supported past research and indicated that aggressive youth high on psychopathic traits showed a reduced responsiveness to distressing stimuli but aggressive youth low on psychopathic traits showed an enhanced responsivity to distressing stimuli. The association with contextual factors revealed that exposure to community violence was correlated with both psychopathic traits and emotional response to distress stimuli. There was also an interaction between psychopathic traits and exposure to community violence that was similar to the interaction found between psychopathic traits and aggression. That is, psychopathy was inversely related to emotional responses to distressing stimuli, but only for youth high on exposure to violence. Both of these interactions suggested that there was a group of youth high on callous-unemotional traits that also showed strong emotional responses to distressing stimuli. Analyses indicated that this group of youth experienced greater levels of abuse, consistent with research showing that abused children tend to be hypervigilant to emotional stimuli but may also show deficits in empathy. These findings suggest that there may be multiple developmental pathways to psychopathy and have important implications for how treatment approaches should be uniquely tailored to the needs of youth in each pathway.

The present study examined the relationship between callous-unemotional (CU) traits and self-reported leadership characteristics during group crimes among 614 first-time offenders participating in a large multi-site study. Resistance to peer influence (RPI) and self-esteem (SE) were hypothesized to mediate the relationship between CU traits and leadership during group crime. The results indicated that youth with CU traits were more likely to commit crimes with others. Further, although youth with CU traits reported they came up with the idea for crimes and were leaders during group crimes, these relationships were not mediated by RPI and SE. Future research on youth with CU traits characteristics during group crimes is recommended and implications for tailored treatments of this population are discussed.

Research supports interventions for high-risk juvenile offenders to reduce recidivism. Methods for assessing delinquent risk vary, however. Aggregate risk scores (i.e. number of risk factors) and specific risk profiles (i.e. types of risk factors) are both empirically supported techniques. This study compared aggregate scores versus profiles for predicting measures of criminal severity among detained adolescents (n=292). Twenty-four risk factors from the Structured Assessment of Violence Risk in Youth (SAVRY) were summed to calculate aggregate scores. Using latent class analysis (LCA), profiles were identified based on scores from the following theoretically important SAVRY risk factors: Risk Taking/Impulsivity, Anger Management Problems, Low Empathy/Remorse (CU traits), and Attention Deficit/Hyperactivity Difficulties. LCA identified one low-risk profile, plus two high-risk profiles differentiated by levels of CU traits. Aggregate scores significantly predicted four out of six criminal severity indicators, while profiles failed to predict any measures. Results support aggregate scores over profiles for assessing delinquent severity.

The current study examined whether a sample of detained male adolescents (n = 107; Mean age = 15.50; SD = 1.30) could be disaggregated into two distinct groups, consistent with past research on primary and secondary variants of callous-unemotional (CU) traits in adolescents. This study also sought to determine a possible explanation for the CU traits among youth in the secondary variant by examining whether they differ from primary variants on measures of cognitive and affective empathy. Using Latent Profile Analyses, two groups of adolescents high on CU traits were identified, a large group (n = 30) high on CU traits but low on anxiety (primary) and a smaller group high on both CU traits and anxiety (n = 10; secondary). Using self-report and computerized measures of affective (e.g., emotional reactivity) and cognitive empathy (e.g., affective facial recognition and theory of mind (ToM)), results revealed that the secondary variant demonstrated the lowest levels of cognitive empathy. In contrast, the primary variant demonstrated the lowest levels of self-report affective empathy, but these levels were not significantly different from the secondary variant. Multiple regression analyses testing the association among measures of empathy, CU traits, and anxiety produced a mostly consistent pattern of results. One exception was the finding of an interaction between CU traits and anxiety in the prediction of fear recognition accuracy that indicated that CU traits were positively associated with accuracy in recognizing fearful facial expressions when anxiety was low. The current study builds upon previous work examining primary and secondary variants of CU traits by suggesting that both primary and secondary variants may exhibit similar deficits in affective empathy, but that secondary variants may also exhibit deficits in cognitive empathy and perspective-taking that are not present in primary variants.

The current study investigated the predictive utility of callous-unemotional (CU) traits and emotional facilitation to distress (EFD) for multiple antisocial outcomes in a sample of juvenile justice-involved males. Although CU traits and EFD did not generally interact to predict antisocial outcomes, CU traits were a consistent predictor of total, proactive, and reactive forms of aggression over 18 months. Similarly, CU traits and time interacted to predict total and violent self-reported offending, such that CU traits were positively associated with both outcomes, but this association weakened over the 18 month timeframe. Racial and ethnic differences only emerged for the prediction of days to any arrest or a violent arrest. Specifically, different factors appear to be important of the prediction of any arrest across racial/ethnic groups, whereas being Black was associated with fewer days to arrest, despite self-reporting similar levels of violent offending. Last, a joint trajectory model for CU traits and EFD was not estimated due to a lack of stability in EFD. However, the majority of the sample exhibited average or increasing levels of CU traits over the 18 month timeframe, highlighting the importance of examining not only the factors that can result in CU traits, but also the factors that can lead to increases in CU traits over time in justice-involved youth.

The current study tested the association of both positive and negative aspects of parenting with callous-unemotional (CU) traits and conduct problems. Caregivers of 92 kindergarteners were recruited to complete a series of survey measures. Overall, parent-report of negative parenting practices was not associated with teacher report of conduct problems. However, parent report of positive parenting practices (i.e., warmth, positive reinforcement, positive communication and cooperation) was negatively associated with conduct problems and CU traits. Interactions between positive parenting variables and CU traits in their association with conduct problems indicated that positive reinforcement related more strongly to lower levels of conduct problem behavior for youth with high levels of CU traits. However, positive communication and cooperation related more strongly to conduct problems for youth with lower levels of CU traits. These associations suggest that parenting may play a role in the development of CU traits and conduct problems.