Tinea pedis is a chronic fungal infection of the feet, very often observed in patients who are immuno-suppressed or have diabetes mellitus. The practicing allergist may be called upon to treat this disease for various reasons. Sometimes tinea infection may be mistaken for atopic dermatitis or allergic eczema. In other patients, tinea pedis may complicate allergy and asthma and may contribute to refractory atopic disease. Patients with recurrent cellulitis may be referred to the allergist/immunologist for an immune evaluation and discovered to have tinea pedis as a predisposing factor. From a molecular standpoint, superficial fungal infections may induce a type2 T helper cell response (Th2) that can aggravate atopy. Th2 cytokines may induce eosinophil recruitment and immunoglobulin E (IgE) class switching by B cells, thereby leading to exacerbation of atopic conditions. Three groups of fungal pathogens, referred to as dermatophytes, have been shown to cause tinea pedis: Trychophyton sp, Epidermophyton sp, and Microsporum sp. The disease manifests as a pruritic, erythematous, scaly eruption on the foot and depending on its location, three variants have been described: interdigital type, moccasin type, and vesiculobullous type. Tinea pedis may be associated with recurrent cellulitis, as the fungal pathogens provide a portal for bacterial invasion of subcutaneous tissues. In some cases of refractory asthma, treatment of the associated tinea pedis infection may induce remission in airway disease. Very often, protracted topical and/or oral antifungal agents are required to treat this often frustrating and morbid disease. An evaluation for underlying immuno-suppression or diabetes may be indicated in patients with refractory disease.

Hidrolipodistrofia ginóide (H.L.D.G.), a celulite, é comumente tratada com cosméticos contendo extratos vegetais. O estudo realizado foi: ultra-sonografia na avaliação da espessura da hipoderme e a microcirculação cutânea; uso de termômetro infravermelho na medida da temperatura e análise das medidas antropométricas da uma formulação cosmética anticelulítica contendo extrato hidroglicólico de Trichilia catigua e Ptychopetalum olacoides Bentham (catuaba e marapuama). Foram realizadas medidas iniciais e após aplicação da formulação. Os resultados apresentaram alterações estatisticamente significativas para a temperatura cutânea e medidas antropométricas. Não houve diferenças estatisticamente significativas nas medidas da hipoderme e microcirculação. Considerando os resultados, a formulação avaliada possui potencial ação coadjuvante na redução da hidrolipodistrofia ginóide. As técnicas podem ser associadas em conjunto com a avaliação sensorial e apreciabilidade cosmética. Os requisitos chaves para a reprodutibilidade das técnicas incluem ambiente controlado, monitoramento e climatização dos voluntários, procedimentos de medidas padronizados, protocolos de aplicação realístico e operadores qualificados. / Gynoid lipodystrophy (H.L.D.G.), the cellulite, is usually treated by cosmetics containing vegetal extracts ingredients. The study related to: ultrasonography evaluating the hypodermis thickness and skin blood microcirculation; the usage of the infra-red thermometer in the measurement of skin temperature and the assessment of anthropometrics measurements of a coadjuvant cosmetic formula based on hydroglycolic extract of Trichilia catigua and Ptychopetalum olacoides Bentham (catuaba and marapuama). Measurements were taken at first and again after the use of the formulation. The results indicate that there were statistically significant changes for skin temperature and also anthropometrics measurements. There were no statistically significant differences neither in hypodermis nor in blood microcirculation. Considering the final results, the formulation studied had a potential coadjuvant role by decreasing gynoid lipodystrophy. These techniques can be associated together with sensory evaluation and cosmetic appreciability. The key requirements for the reproducibility of the technique include: controlled environments, volunteers acclimatization and monitoring, standardized measurements procedures, realistic application protocols and qualified operators.

Hidrolipodistrofia ginóide (H.L.D.G.), a celulite, é comumente tratada com cosméticos contendo extratos vegetais. O estudo realizado foi: ultra-sonografia na avaliação da espessura da hipoderme e a microcirculação cutânea; uso de termômetro infravermelho na medida da temperatura e análise das medidas antropométricas da uma formulação cosmética anticelulítica contendo extrato hidroglicólico de Trichilia catigua e Ptychopetalum olacoides Bentham (catuaba e marapuama). Foram realizadas medidas iniciais e após aplicação da formulação. Os resultados apresentaram alterações estatisticamente significativas para a temperatura cutânea e medidas antropométricas. Não houve diferenças estatisticamente significativas nas medidas da hipoderme e microcirculação. Considerando os resultados, a formulação avaliada possui potencial ação coadjuvante na redução da hidrolipodistrofia ginóide. As técnicas podem ser associadas em conjunto com a avaliação sensorial e apreciabilidade cosmética. Os requisitos chaves para a reprodutibilidade das técnicas incluem ambiente controlado, monitoramento e climatização dos voluntários, procedimentos de medidas padronizados, protocolos de aplicação realístico e operadores qualificados. / Gynoid lipodystrophy (H.L.D.G.), the cellulite, is usually treated by cosmetics containing vegetal extracts ingredients. The study related to: ultrasonography evaluating the hypodermis thickness and skin blood microcirculation; the usage of the infra-red thermometer in the measurement of skin temperature and the assessment of anthropometrics measurements of a coadjuvant cosmetic formula based on hydroglycolic extract of Trichilia catigua and Ptychopetalum olacoides Bentham (catuaba and marapuama). Measurements were taken at first and again after the use of the formulation. The results indicate that there were statistically significant changes for skin temperature and also anthropometrics measurements. There were no statistically significant differences neither in hypodermis nor in blood microcirculation. Considering the final results, the formulation studied had a potential coadjuvant role by decreasing gynoid lipodystrophy. These techniques can be associated together with sensory evaluation and cosmetic appreciability. The key requirements for the reproducibility of the technique include: controlled environments, volunteers acclimatization and monitoring, standardized measurements procedures, realistic application protocols and qualified operators.

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