Dissertation submitted to the Faculty of Dentistry, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Dentistry. / Growth and development of the skull is influenced by metabolic factors such as the endocrinopathies. The purpose of this study is to examine the effects of induced hypothyroidism on growth and development of the skull of the Vervet monkey. Seven infant monkeys of the subspecies Ceraop-ithecus aethiops cloetei were selected as the experimental animals in this study. Two of the seven monkeys were used as the control group, the remaining five monkeys were given radio-active iodine to depress their thyroid activity. Cephalometric records were taken of the animals for a period of approximately one year, at the end of which time they were sacrificed. At the age of 15 months the radiographs of the hypothyroidic monkeys, when compared to those of the control group, exhibit marked differences in cranial form. However, the most marked changes are seen in the cranial vaults of the experimental animals. Some of the findings are examined in the light of a number of theories which have been proposed for the control of the growth and development of the skull. / WHSLYP2017

Bibliography: leaves 342-392. I: Introduction. Ch. 1. The Le Fort I osteotomy for the correction of maxillary position in three dimensions -- II: Review of the literature. Ch. 2. Dentofacial discrepancies involving the maxilla -- Ch. 3. Cephalometry -- Ch. 4. Relapse following Le Fort I osteotomy -- Ch. 5. Factors associated with post surgical relapse following Le Fort I osteotomy -- Ch. 6. Biomechanics of fixation -- III: Materials and method. Ch. 7. Evaluation of post surgical relapse -- Ch. 8. Errors of method -- IV: Results. Ch. 9. Early, intermediate and long term dentoskeletal effect following Le Fort I osteotomy -- Ch. 10. Results: Errors of the method -- V: Discussion. Ch. 11. Discussion of experimental design -- Ch. 12. Discussion of factors in the relapse of Le Fort I osteotomy -- VI: Conclusion. Ch. 13. Conclusion. -- VII: Appendix. i. Bone grafts ; ii. Le Fort I osteotomy surgical technique ; iii. Bone plate removal protocol statement.

Thesis (M.D.S.)--University of Hong Kong, 1997. / Includes bibliographical references (leaves 244-306) Also available in print.

Thesis (M.D.S.)--University of Hong Kong, 1991. / Includes bibliographical references (p. 258-271). Also available in print.

Thesis (M.D.S.)--University of Adelaide, Dept. of Dentistry, 1999. / Bibliography: leaves 342-392.

Thesis (M.S.)--University of Michigan, 1976.

Thesis (M.S.)--University of Michigan, 1972. / Typescript (photocopy). Includes bibliographical references (leaves 55-60). Also issued in print.

Thesis (M.S. )--University of Tennessee Health Science Center, 2007. / Title from title page screen (May 16, 2008). Research advisor: Edward F. Harris, PhD. Document formatted into pages (x, 189 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 110-123).

Thesis (M.S.) --University of Texas Graduate School of Biomedical Sciences at San Antonio, 2008. / Vita. Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 1966.