No description available.

No description available.

Orientador: Jorge Sidney Coli Júnior / Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciências Humanas / Made available in DSpace on 2018-08-19T16:21:05Z (GMT). No. of bitstreams: 1 Marins_DirceuCarlos_D.pdf: 12469254 bytes, checksum: a5f688b813a1ecb14cc07ff2da39c473 (MD5) Previous issue date: 2012 / Resumo: A partir dos filmes dirigidos pelo cineasta norte-americano Clint Eastwood, a pesquisa procura estabelecer uma apreciação dessa produção audiovisual através da paisagem. As relações indiciárias encontradas traçam motivos estéticos que se tomou por um estilo flutuante. A tese central é a de como os afetos e as locações/paisagens compõem efeitos poéticos e actanciais dentro desse estilo. Esses recursos são observados em suas modulações e efeitos recorrentes, ao longo de toda a filmografia do cineasta. A paisagem nos filmes - tomada aqui como os cenários naturais e naturados, tanto geográficos quanto meteorológicos - é estudada como elemento narrativo e, ao mesmo tempo, iconográfico. As modulações de suas aparições são tecidas a par de personagens outsiders e seus afetos no cinema do diretor, através da seleção de fotogramas/frames (cenas, sequências e planos sequência) de alguns de seus filmes. Assim, a pesquisa se apresenta em duas partes principais: I) filmografia completa, com detalhes técnicos e indicações do comportamento das tramas e das paisagens (na maior parte das obras); II) recortes específicos de algumas obras e de suas paisagens, por tópicos que conversam por entre diferentes filmes e períodos da filmografia do diretor. Relações com a pintura e outros diretores estabelecem, também, uma moldura de recursos estilísticos que atravessam essas composições audiovisuais / Abstract: By directed films of northamerican filmmaker Clint Eastwood the tesis accomplished an appreciation of this audiovisual production through landscape. The clues relations found marks esthetical motives that take it for a floating style. The central thesis is how the affections and the locations/landscapes compound poeticals and actancials effects into this style. This resources are watching in his modulations and recurring effects toward all filmography by the filmmaker. The landscape in the movies - take it here like the natural and naturated scenarios, also geographical and meteorological - is studied like narrative element and, at the same time, iconographical. The modulations of his appearance are tailoring by the side of outsiders characters and his affections in the cinema of the director, by selected frames (scenes, sequences and plan-sequences) of some of his movies. Thus the research shows in two principal parts: I) complete filmography with technical details and indications of the behavior of plots and the landscapes (in most of the works); II) specific cuttings of some of this works and his landscapes by topics that talk between different movies and periods of the filmography of the director. Relationships with the painting and other directors establishes too a frame of stylistic resources that crossing this audiovisuals compositions / Doutorado / Historia da Arte / Doutor em História

This paper is on propaganda in Clint Eastwoods American Sniper (2014). With this film in focus I have conducted a qualitative discourse analysis to extract subtle hints of propaganda in selected scenes from the film. I proceed from theories that discuss propaganda, orientalism and us-and-them, but I have also researched government pressures on film, and media research on its influence on people. This paper shows in combination with these theories that propagandistic messages can be identified through mainly the use of us-and-them. In American Sniper (2014) the image of USA is strengthen by establishing a negative and wrongful portrayal of their counterparts, making them nothing but evil or helpless.

This diploma thesis analyses two films by Clint Eastwood Million Dollar Baby and American Sniper. Its focus is aimed at the formal storytelling aspects, structure of the storyline and plot devices in the screenplays. The first film is an example of misusing these plot devices; the theme being euthanasia remains irrelevant from the viewers perspective although it was meant to resonate strongly at first. Analysis of the second film shows us the discrepancy of what the film "wanted" to be and the actual message it implicitly presents to the audience. Instead of being an objective reflection of the real events (in this case the war in Iraq) it is on purpose misleading in presenting of commonly known facts and hence it becomes propaganda. The analysis of the storytelling devices in this thesis can be also applied on different films and cinema in general.

The elimination of drugs from the body is in many cases performed by the liver. Much could be gained if an accurate prediction of this process could be made early in the development of new drugs. However, for the elimination to occur, the drug molecule needs first to get inside the liver cell. Disposition is the expression used to encapsulate both elimination and distribution. This thesis presents novel approaches and models based on simple in vitro systems for the investigation of processes involved in the hepatic drug disposition. An approach to the estimation of enzyme kinetics based on substrate depletion data from cell fractions was thoroughly evaluated through experiments and simulations. The results that it provided were confirmed to be accurate and robust. In addition, a new experimental setup suitable for a screening environment, i.e., for a reduced number of samples, was generated through optimal experimental design. The optimization suggested that sampling at late time points over a wide range of concentration was the most advantageous. A model, based on data from primary hepatocytes in suspension, for the investigation of cellular disposition of metabolized drugs was developed. Information on the relative importance of metabolism and membrane protein related distribution was obtained by analysis of changes in the kinetics by specific inhibition of the various processes. The model was evaluated by comparing the results to those obtained from an in vivo study analyzed with an especially constructed mechanistic PBPK model. These investigations showed that the suggested model produced good predictions of the relative importance of metabolism and carrier mediated membrane transport for hepatic disposition. In conclusion, new approaches for the investigation of processes involved in hepatic disposition were developed. These methods were shown to be robust and increased the output of information from already commonly implemented in vitro systems.