Five resorts in East Tennessee--Montvale Springs and the Wonderland Hotel in the Smokies, Tate Spring in the Holston River Valley, Unaka Springs on the Nolichucky River, and the Cloudland Hotel at the summit of Roan Mountain--stand testament to the proposition that their region engaged fully with areas outside southern Appalachia. Their origins, clientele, and health and leisure offerings followed those of other resorts of the same time period. Moreover, the effects of national socioeconomic trends on the hotels serve as a contradiction to the stereotype of southern Appalachia as an isolated region barricaded from the outside world by mountainous topography. The East Tennessee resorts covered in this thesis indicate that the region as a whole was emblematic of national socioeconomic and cultural trends.