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Controlled release technology : development of a slow release systemic repellent for the protection of tree seedlings from deer /Gustafson, David I. January 1983 (has links)
Thesis (Ph. D.)--University of Washington, 1983. / Vita. Bibliography: leaves [202]-216.
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Tocopherol stability in controlled release packaging filmsLang, Jillian C. January 2009 (has links)
Thesis (M.S.)--Rutgers University, 2009. / "Graduate Program in Food Science." Includes bibliographical references (p. 186-195).
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Development of target release rate concept for controlled release packagingZhu, Xuntao. January 2008 (has links)
Thesis (Ph. D.)--Rutgers University, 2008. / "Graduate Program in Food Science." Includes bibliographical references (p. 184-190).
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Nanoengineered implantable devices for controlled drug deliverySinha, Piyush Mohan, January 2005 (has links)
Thesis (Ph. D.)--Ohio State University, 2005. / Title from first page of PDF file. Document formatted into pages; contains xxii, 220 p.; also includes graphics (some col.). Includes bibliographical references (p. 202-220). Available online via OhioLINK's ETD Center.
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Polymer structural features contributing to mucoadhesionLeung, Sau-Hung Spence. January 1987 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1987. / Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 159-183).
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In situ chemical oxidation of TCE-contaminated groundwater using slow permanganate-releasing materialWang, Sze-Kai 03 August 2011 (has links)
The purpose of this study was to use controlled release technology combining with in situ chemical oxidation (ISCO) and permeable reactive barrier (PRB) to remediate TCE-contaminated groundwater. In this study, potassium permanganate (KMnO4) releasing material was designed for potassium permanganate release in groundwater. The components of potassium permanganate releasing material included poly (£`-caprolactone) (PCL), potassium permanganate, and starch with a weight ratio of 2:1:0.5. Approximately 63.8% (w/w) of potassium permanganate was released from the material after 76 days of operation. The released was able to oxidize contaminant in groundwater. Results from the solid oxidation demand (SOD) experiment show that the consumption rate increased with increased contaminant concentration. TCE removal efficiency increased with the increased TCE concentration. The second-order rate law can be used to simulate the TCE degradation trend. In the column experiment, results show that the released MnO4- could oxidize TCE and TCE degradation byproducts when 95.6 pore volume (PV) of contaminated groundwater was treated. More than 95% of TCE removal can be observed in the column study. Although the concentration of manganese dioxide (MnO2) began to rise after 8.8 PV of operation, TCE removal was not affected. Results also show that low level of hexavalent chromium was detected (< 0.05 mg/L). Results from the scanning electron microscope (SEM) and energy-dispersive spectroscope (EDX) analyses show that the amounts of manganese and potassium in the materials decreased after the releasing experiment. Results indicate that the concentration of TCE and SOD need to be analyzed before the releasing materials are applied in situ. In the practical application, the releasing materials will not become solid wastes because they are decomposed after use. If this slow-releasing technology can be combined with a permeable reactive barrier system, this technology will become a more economic and environmentally-friendly green remedial system.
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Delivery of a coated bioactive from a rumen controlled-release deviceSyzov, Vladyslav. January 2008 (has links)
Thesis (M.E.)--University of Waikato, 2008. / Title from PDF cover (viewed September 18, 2008) Includes bibliographical references (p. 66-70)
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DNA-LPEI complexes encapsulated in LTP nanospheres as a non-viral gene therapy vectorDitto, Andrew. January 2006 (has links)
Thesis (M.S.)--University of Akron, Dept. of Biomedical Engineering, 2006. / "December, 2006." Title from electronic thesis title page (viewed 12/31/2008) Advisor, Yang Yun; Committee members, Stephanie Lopina, Steven Schmidt; Department Chair, Daniel Sheffer; Dean of the College, George K. Haritos; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.
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Design of systems for time delayed activated internal release of chemicals in concrete from porous fibers, aggregates of prills, to improve durability /Dry, Carolyn. January 1991 (has links)
Thesis (Ph. D.)--Virginia Polytechnic Institute and State University, 1991. / Vita. Abstract. Includes bibliographical references (leaves 179-181). Also available via the Internet
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Preparação e caracterização de microparticulas de hialuronato de sodio para encapsulação e liberação controlada de proteinas para aplicação nasal / Preparation and characterization of sodium hyaluronate microparticles for encapsulation and controlled release of proteins for nasal applicationKubo, Tatiana Miyuki Ogawa 25 May 2005 (has links)
Orientador: Maria Helena Andrade Santana / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica / Made available in DSpace on 2018-08-04T23:14:50Z (GMT). No. of bitstreams: 1
Kubo_TatianaMiyukiOgawa_M.pdf: 3390196 bytes, checksum: 90fbf573dfcb12a87da26f2fdcbfb4dd (MD5)
Previous issue date: 2005 / Resumo: Neste trabalho foi feito o estudo da preparação de microesferas de hialuronato de sódio pelo método de emulsificação e evaporação de solvente, utilizando temperatura como agente de retificação física. O assunto foi abordado com ênfase na influência das condições operacionais do processo nas propriedades físico-químicas das microesferas e na sua capacidade de incorporação de proteínas, visando atender os requisitos da administração nasal. Inicialmente, a albumina de soro bovino foi usada como proteína modelo e, na segunda etapa, a ovoalbumina foi incorporada nas melhores condições do processo. Para conferir maior resistência mecânica às partículas e prolongar o tempo de liberação da proteína encapsulada, foi utilizado um segundo método de preparação, também por emulsificação, porem com reticulação química feita pela ligação cruzada (crosslinking), com dihidrazida adípica (ADH) em meio aquosos. As microesferas foram caracterizadas pelo seu diâmetro médio e distribuição de tamanhos, morfololgia, cristalinidade, mucoadesividade, intumescimento, eficiência de encapsulação e perfil de liberação das proteínas encapsuladas, eficiência de encapsulação e perfil de liberação das proteínas encapsuladas. Para as partículas reticuladas com ADH, o grau de reticulação foi correlacionado com a sua capacidade de intumescimento e com a cinética de liberação da proteína. Esses efeitos foram caracterizados através do coeficiente de difusão da ovoalbumina nas partículas com diferentes graus de reticulação... Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da tese digital / Abstract: This work describes the study of sodium hyaluronate microspheres preparation through the emulsification and solvent evaporation technique, using temperature as the physical crosslinking agent. The subject was analyzed with emphasis on the influence of the process operations conditions on the physical and chemical properties of the microspheres and on its protein encapsulation capacity, willing to attend the nasal administration requirements. Initially, bovine serum albumin (BSA) was used as model protein, and in the second step, ovoalbumin (OVA) was incorporated using the best process conditions. In order to improve the mechanical resistance of the particles and extend the release time of the encapsulated protein, a second preparation method, also based on an emulsification but involving a chemical crosslinking reaction using adipic dihidrazide (ADH) in an aqueous solution, was evaluated. The microspheres were characterized by the mean diameter and size distribution, morphology, cristallinity, mucoadhesiveness, swelling capacity, encapsulation efficiency and release profile of the encapsulated proteins. For the particles crosslinked with ADH, the degree of crosslinking was correlated to the swelling capacity and with the protein release kinetics. These effects were characterized by the diffusion coefficient of ovoalbumin from the particles with different crosslinking degrees. The results showed the feasubillity of the sodium hyaluronate microspheres production, its protein encapsulation capability and the flexibility to modulate its properties according to the process conditions... Note: The complete abstract is available with the full electronic digital thesis or dissertations / Mestrado / Desenvolvimento de Processos Biotecnologicos / Mestre em Engenharia Química
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