The work become acquainted with history and rise databases globally. Construes philosophy structuralization, sorting and purpose using. Work further deal with concrete databases softwares intended directly to processing audio signals. Further treat of programmes that the make possible generation personal database structures. Work deal about SUSAS database and analysing its content. It is created self database of music signals, which includes several musical groups always similar in certain aspect. Speech database contains records from the SUSAS database and records from television programs, reality-shows, sports broadcasts, reports and documents, when speakers are subjected to stress and emotions. The work is a database program that can effectively classify all records and processes. The database can be freely extended. The resulting program was realized into Czech and English version.

Of all of the desktop software available, that for the implementation of a database is some of the most complex. With the increasing number of computer users having access to this sophisticated software, but with no obvious way to learn the rudiments of data modelling for the implementation of a database, there is a need for a simple, convenient method to improve their understanding. The research described in this thesis represents the first steps in the development of a tool to accomplish this improvement. In a preliminary study using empirical research a conceptual model was used to improve novice end users’ understanding of the relational concepts of data organisation and the use of a database software package. The results showed that no conclusions could be drawn about either the artefact used or the method of evaluation. Following the lead of researchers in the fields of both education and information systems, a design research process was developed, consisting of the construction and evaluation of a training artefact. A combination of design research and a design experiment was used in the main study described in this thesis. New to research in information systems, design research is a methodology or set of analytical techniques and perspectives, and this was used to develop a process (development of an artefact) and a product (the artefact itself). The artefact, once developed, needed to be evaluated for its effectiveness, and this was done using a design experiment. The experiment involved exposing the artefact to a small group of end users in a realistic setting and defining a process for the evaluation of the artefact. The artefact was the tool that would facilitate the improvement of the understanding of data modelling, the vital precursor to the development of a database. The research was conducted among a group of novice end users who were exposed to the artefact, facilitated by an independent person. In order to assess whether there was any improvement in the novices’ understanding of relational data modelling and database concepts, they then completed a post-test. Results confirmed that the artefact, trialled through one iteration, was successful in improving the understanding of these novice end users in the area of data modelling. The combination of design research and design experiment as described above gave rise to a new methodology, called experimental design research at this early juncture. The successful outcome of this research will lead to further iterations of the design research methodology, leading in turn to the further development of the artefact which will be both useful and accessible to novice users of personal computers and database software. This research has made the following original contributions. Firstly, the use of the design research methodology for the development of the artefact, which proved successful in improving novice users’ understanding of relational data structures. Secondly, the novel use of a design experiment in an information systems project, which was used to evaluate the success of the artefact. And finally, the combination of the developed artefact followed by its successful evaluation using a design experiment resulted in the hybrid experimental design research methodology. The success of the implementation of the experimental design research methodology in this information systems project shows much promise for its successful application to similar projects.

Indiana University-Purdue University Indianapolis (IUPUI) / The literature corresponding to disordered proteins has been on a rise. As the number of publications increase, the time and effort needed to manually identify the relevant publications and protein information to add to centralized repository (called DisProt) is becoming arduous and critical. Existing search facilities on PubMed can retrieve a seemingly large number of publications based on keywords and does not have any support for ranking them based on the probability of the protein names mentioned in a given abstract being added to DisProt. This thesis explores a novel system of using disorder predictors and context based dictionary methods to quickly identify publications on disordered proteins from the PubMed database. NLProt, which is built around Support Vector Machines, is used to identify protein names and PONDR-FIT which is an Artificial Neural Network based meta- predictor is used for identifying protein disorder. The work done in this thesis is of immediate significance in identifying disordered protein names. We have tested the new system on 100 abstracts from DisProt [these abstracts were found to be relevant to disordered proteins and were added to DisProt manually by the annotators.] This system had an accuracy of 87% on this test set. We then took another 100 recently added abstracts from PubMed and ran our algorithm on them. This time it had an accuracy of 68%. We suggested improvements to increase the accuracy and believe that this system can be applied for identifying disordered proteins from literature.