Cognitive behavior theory indicates that situational determinants may have a substantial impact on substance use and relapse into use. The present study described situational use of marijuana in dependent individuals, analyzed relationships among various constructs in existing theory, determined their effects on treatment outcomes, and explored interactions with self-efficacy. Results were generally consistent with hypotheses. Use in negative affective situations was independently associated with psychological distress, maladaptive coping strategies, and poorer outcomes post-treatment. Additionally, negative affective use interacted with self-efficacy for psychologically distressing situations to produce differential outcomes. This study adds to the existing literature on situational marijuana use by establishing relationships with motives for use and lending support to the cognitive behavioral theory model. / Master of Science

Yes / Research on business growth has blossomed, yet scholars often complain face the difficulty of distililing a clearer pitcure of the business growth phenomenon. This paper attempts to overcome this limitation by reviewing and synthesizing extant research on business growth. First, we begin by examining Penrose’s view of firm growth. Second, we highlight how business growth is measured; these are absolute or relative change and growth as a process. Third, we explore theories of business growth; integrated models-theories that explain the factors that drive business growth and (2) stage models which view business growth as a series of phases or stages of development through which a firm must pass in its life-cycle. Fourth, we examine modes of business growth; these are organic vs. acquisition growth, growth through networks and alliances and growth through internationalization. Fifth, we examine drivers and constraints to business growth. We conclude the review by pointing out areas of harmony and contention in the literature, from which we suggest opportunities for future research.

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這是關於成功的海外財務中心的決定因素 / This is a thesis about The Determinants of a Successful Offshore Finance Center

This dissertation investigates the determinants of economic growth in China since 1978, with a focus on the determinants of spatial growth. A study of the theories of economic growth shows that both proximate and fundamental factors can contribute to economic growth. In the case of China, institutional changes are the keys to the Chinese transitional economy. Given the special nature of China's economy, the main institutional reforms since 1978 are examined, together with the gradual transition process. Furthermore, from the overview of empirical literature, it is found that the proximate determinants such as initial gross domestic product (GDP), investment, population growth, human capital and openness are determinants of economic growth in China based on the findings in cross-country growth literature. From growth accounting exercises, capital formation and total factor productivity (TFP) growth can be seen to play important roles in the rapid economic growth in China. However, while the nationwide economic growth is impressive, the pace of reform and economic development has been uneven across provinces. In the existing literature, geography and preferential policy are emphasised as particular factors that affect coastal-interior disparity. This study incorporates the economic variables identified as important stimulants to growth, drawing on major findings in the study of convergence and economic growth to estimate the determinants of regional economic growth in China. To address the weaknesses of using ordinary least squares (OLS) for cross-country regression analyses, fixed-effects ordinary least squares (OLS) and random-effects generalised least squares (GLS) panel data estimators are applied to provincial data from 1994 to 2003. It is concluded that the convergence hypothesis does not hold in China, and that export, investment, education, foreign direct investment (FDI) growth and coastal dummy have a positive effect on regional GDP per capita growth in China while population growth affects the annual growth rate negatively. / Thesis (M.Com. (Economics))--North-West University, Potchefstroom Campus, 2006.

This study is aim to evaluate the effect of five factors on the amount of tourists arrivals to China in those countries who have most visitors. To apply empirical estimation, a balanced panel data based gravity equation is established, with 22 countries and 15 years period (1998 - 2002). Our main estimates conclude that GDP per capita has a positive impact on the amount of tourists, as well as population, whereas exchange rate and distance will deter the amounts of tourists. Unfortunately PPP conversion factor also has a positive impact but not as expected. The findings of this study will fill the gap of relative literatures for China and provide another evidence of gravity model.

MSc (Med), Population-Based Field Epidemiology, Faculty of Health Sciences, University of the Witwatersrand / Introduction: As people age, they become more vulnerable to ill‐health from acute and increasingly chronic diseases. This has elevated health care demand and utilisation in the elderly especially in the developed countries. In developing countries, ageing so far has not been a serious public health concern because of smaller number of older people in these countries. Recently however, the number of older adults in Sub‐Saharan Africa has increased rapidly, projected to stand at 130 million by 2050 from 30 million in 2000. This increase mirrors health related problems and has obvious public health implications. Thus, there is an urgent need to recognise and respond to health needs of the ageing populations in Africa. Objectives: To describe health care utilisation, health status and compare the proportions of adults aged 50+ years with moderate and poor health status to those with good health status. Another objective was to identify factors associated with health care utilisation among the elderly population in Kassena‐Nankana district, Ghana in 2007. Methods: Secondary analysis was performed on a cross‐sectional dataset collected between February and July 2007 through face‐to‐face interviews within the settings of the Navrongo DSS in Ghana. A total of 594 adults aged 50+ years participated in this study. The outcome variable was health care utilisation occurring in the last three years. Explanatory variables were grouped as predisposing, enabling and need‐related factors according to the behavioural model of health services utilisation. The predisposing variables were age, sex, marital status, ethnic background, education and smoking or use of smokeless tobacco. Occupation and financial position were included as enabling factors. Medical history of chronic conditions, self‐reported health status, difficulty with self‐care (e.g. bathing, washing, dressing etc), difficulty with picking up things in the last 30 days and cognitive impairment were grouped as need‐related factors. Logistic 382128 v univariate and multivariate regression analyses were conducted. STATA 10 statistical software was used to carry out this process. Results: The proportion of study participants reporting poor, moderate and good health status were 14.2%, 43.3% and 42.5% respectively. About one‐third (31%) of the study participants reported to have utilised health care services in the last 3 years. The following factors were identified as determinants of health care utilisation among the elderly rural Ghanaians: a medical history of at least one chronic condition (OR = 2.36; 95% CI = [1.49 – 3.75]; p < 0.001), self‐perceived health (OR = 2.00; 95% CI = [1.11 ‐ 3.59]; p = 0.021), age group (OR = 1.68; 95% CI = [1.07 ‐ 2.64]; p = 0.025), cognitive impairment (OR = 1.26; 95% CI = [1.02 – 1.56]; p = 0.032) and difficulty with picking up things in the last 30 days (OR = 0.76; 95% CI = [0.61 ‐ 0.96]; p = 0.021). Conclusion: Medical history of at least one chronic condition and poor perceived health status were the most pervasive determinants of health care utilisation. In addition, age group (60‐69 years), severe cognitive impairment and severe difficulty with picking up things in the last 30 days presented a significant influence on health care utilisation among the elderly population in rural Ghana. Recommendations: Provision of home‐based health care services could facilitate their accessibility for the elderly especially those with various difficulties. These factors could help health policy makers and health service providers identify and understand the situation of the elderly rural Ghanaians and consequently create conducive environment for providing appropriate health care services.

A closely related factor to economic growth is FDI - Foreign Direct Investment. Foreigninvestment in a country made in order of utilizing specific markets or certaincharacteristics of a region. Sub-Saharan Africa is a region receiving remarkably smallfraction compared to its peer regions considering the sources of natural resources andother riches. The purpose of the thesis is to find the determinants of FDI in Sub-SaharanAfrica. The determinants are a selected set of variables based on the research of previousstudies in the field of study. A panel data regression is performed for 23 Sub-Saharancountries with data from 1997 to 2017. The result of the regression demonstrated similarresults regarding the affiliation between the variables of the model and the independentvariable, FDI as previous studies. The findings of the study do not answer the question ofwhy certain other regions of developing economies receive larger amounts ofinvestments. However, our hope is that the findings of this study will gain furtherresearch on the area

The anticipated risk of job loss and material insecurity are related to fertility postponement in the same way as unemployment is. Given the sequential nature of fertility and occupational decisions, unfavorable working conditions should be resolved before having children, and result in an increase in people's assignment of importance to paid work when developing their childbearing plans. We aim to demonstrate this link, focusing on perceived employment and material insecurity, the importance assigned to paid work in forming fertility intentions, the construction of fertility intentions, and their realization. Using two waves of the Austrian Generations and Gender Survey, we apply probit regressions to analyze gender variations in the associations between uncertainty conditions, the importance of paid work, fertility intentions and behavior. Results reveal that work and related benefi ts become salient when they are insecure, and that material insecurity among men discourages childbearing. For women, we find support for the hypothesis that the anticipated risk of job loss inhibits the realization of fertility intentions - intentions which are less likely to be constructed under such conditions from the onset of family planning processes.

Antibody engineering is an innovative field of research that has generated a wide range of novel antibody-based formats that both exploit and improve natural antibody properties. Novel format antibodies have the potential to offer significant advantages over natural antibodies when used as biopharmaceuticals, however these non-natural structures often pose a great challenge to the host cell used for their manufacture. Protein expression is a highly regulated process, and quality control mechanisms at each stage can result in a block, or "bottleneck" in expression. This can impact product yield, cost of goods and entry into the clinical pipeline. The molecular determinants that govern novel-format expression in host cells are poorly defined, however there is growing evidence that limited variations in both nucleotide and amino acid sequence can have a severe impact on antibody expression. Therefore this Thesis aims to investigate the consequences of sequence variation on the expression of a novel antibody format (mAbdAb) in mammalian host cells in order to determine the molecular mechanisms that govern their expression. A diverse panel of mAbdAbs with sequence variations limited to the dAb domain were generated through phage display and cloning technologies. It was determined that amino acid variations located within the CDRs of the dAb results in a range of expression titres in both transient HEK and stable CHO expression platforms. In vitro translation of mAbdAb heavy chain proteins in rabbit reticulocyte lysates (RRL) showed no difference in expression between sequence variants, therefore cell-free translation was suggested as a potential expression platform. Examination of each stage of expression in stable CHO cells revealed that the amount of mRNA was not limiting to expression and distinct expression profiles were observed at the protein level. The majority of mAbdAb constructs showed little evidence of intracellular heavy chain polypeptide which was not altered through chemical inhibition of proteolytic degradation pathways, indicating that degradation was not responsible for poor expression. This led to the hypothesis that low titres were related to how the CHO cell utilises the heavy chain message.