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No description available.

The sex-determining gene on the Y chromosome, named Sry, initiates differentiation of gonadal somatic cells into testes, which in turn regulate the development of male phenotype. / The B6.YTIR sex-reversed mouse provides a good model for studying sex-determining mechanisms. We proposed a hypothesis that the testis-determining pathway is impaired downstream of Sry transcription in the B6.YTIR fetus. / The current study aimed to determine the hierarchical order of Sry, Sox9, Pn1, and Mis by examining their expression in B6.YTIR gonads as compared to normal B6.XY gonads by RT-PCR. / Results. Sry expression was comparable between B6.Y TIR and B6.XY gonads, with its onset between 10.5 and 11.5 dpc, a peak at 11.5 dpc, and downregulation thereafter. Sox9 expression was detectable in both B6.XX and B6.XY gonads at 11.5 dpc at comparable levels, but was then downregulated in B6.XX gonads at 12.5 dpc, by which stage testicular cord formation had began in B6.XY gonads. Pn1 was expressed in both B6.XX and B6.XY gonads at comparable levels at 11.5 dpc and was upregulated in B6.XY gonads at 12.5dpc. Mis expression in B6.Y TIR gonads was low at 10.5 and 11.5 dpc with a peak at 12.5dpc and higher levels only in ovotestes at 14.5dpc. / These results indicate that all Sox9, Pn1, and MIS genes follow a sexually dimorphic pattern of expression associated with development of testicular cords. Therefore, these genes are placed downstream of Sry in the fetal mouse gonad. Furthermore, we conclude that the testis-determining pathway is impaired upstream of Sox9 and Pn1 and Mis in the B6.YTIR gonad. (Abstract shortened by UMI.)

In this thesis, I proposed that individuals high in relative autonomy toward exercise would make fewer excuses for personal goal failures and that endorsement of certain types of excuses would foster commitment/internalization toward exercise, limiting future excuse-making. Excuses were expected to vary in effectiveness at removing culpability and enhancing commitment. In 3 studies, relative autonomy was measured or primed. Participants considered past personal goal failures, and sometimes provided excuses, and in one study, participants received expert excuse tolerant/intolerant feedback. Contrary to predictions, excuse-making was similar across all levels of relative autonomy. The results showed, however, that (a) some excuses effectively remove culpability for failure and maintain commitment to exercise goals; (b) such excuses are used more frequently than their less effective counterparts and that this selective may be stronger for those high in relative autonomy toward exercise; and (c) an excuse-tolerant social environment can foster commitment/internalization of exercise goals.

A plethora of anthropological studies have been undertaken on the skull, including many analyses of sexual dimorphism. Sexual dimorphism reflected in the eye orbits has not always demonstrated consistent or reliable results. However, recent studies (Pretorius, Steyn, & Scholtz, 2006; Ji et al., 2010) suggest some positive results utilizing geometric morphometrics to predict sex. Utilizing 97 post-mortem CT (computed tomography) scans, established morphological and metric techniques for sex determination were assessed from 3D rendered models of the crania. In addition, landmark data were collected on the orbital margin to evaluate the accuracy of sex determination using geometric morphometric techniques. Traditional methods demonstrated poor levels of accuracy for prediction of sex, however, utilizing generalised procrustes analysis and discriminant function analysis on 3D landmark data resulted in 94.95% overall accuracy. Application of recent methodological advances, including geometric morphometrics, should continue to be developed as it increases the ability to assess sexual dimorphism which will allow for greater identification of unknown remains.

The development of a small spacecraft attitude determination and control subsystem is described. This subsystem is part of The Space Flight Laboratory's Generic Nanosatellite Bus. With a 20cm3 body, the bus has an attitude determination and control subsystem capable of full three-axis stabilization and control enabling more advanced missions previously only possible with bulkier and more power-consuming attitude control hardware. Specific contributions to the Space Flight Lab's attitude control hardware are emphasised. Particularly, the full development of a 32g three-axis nanosatellite rate sensing unit is described. This includes embedded software development, skew calibration, hardware modeling and qualification testing for the unit. Development work on a three-axis boom-mounted magnetometer is also detailed. A full hardware design is also described for a new microsatellite-sized rate sensor. Larger and more powerful than the nanosatellite rate sensors, the design ensures a low noise, low drift architecture to improve attitude determination on future microsatellite missions.

Contributions to two missions are presented. The first is a demonstration mission called CanX-7 that uses a 4 square metre drag sail to de-orbit a 3.5 kg satellite. In order to estimate the effectiveness of the drag sail, a novel method is developed that takes into account the time-varying nature of the projected drag area. The Space Flight Laboratory designed drag sail is shown to be sufficient to de-orbit the CanX-7 spacecraft within the 25 year requirement. The Antarctic Broadband demonstrator spacecraft is a 20 cm cubical nanosatellite that will demonstrate the feasibility of a Ka-band link between the research community in Antarctica and stakeholders in Australia. In support of this mission, a passive thermal control subsystem is designed that will keep all the components within their operational temperature limits at all times throughout the mission.

The issue of Kurdish self-determination within the highly centralized Republic of Turkey has been a controversial issue with its local, national and international dimensions over the years. Without solving this issue, Turkey might not reach the aims of joining the European Union (EU), economic sustainability, literal democracy, pluralism, and peace. After 40 years armed struggle between Kurdish and Turkish sides, two significant suggestions are currently being discussed: a provincial system similar to what the Ottoman Empire accepted with its own multicultural system; second, the current unitary system with more powerful local authorities. This paper analyzes the problem in an inductive method and takes the second approach to evaluate Turkish centralization, modernization, and transformation to French Republicanism. This evaluation concludes with the critique of the French universal citizenship understanding and requirement of more pluralistic, democratic citizenship and administrative model as a solution of minority rights and self-determination problem in Turkey.

Motivation är en betydelsefull kompontent för en individs utövande utav studier. Studien utgick ifrån motivationsteorin Self- determination theory. Syftet med studien var att redogöra för relationen mellan högskolestudenters demografiska faktorer och vilken typ av motivation som driver dem till att utöva studier, samt relationen mellan motivationstyperna. Med typ av motivation avses amotivation, inre samt yttre motivation. Studien bestod utav 102 studenter, varav 49 män och 53 kvinnor, från en högskola i mellersta Sverige som fick besvara enkäten The Academic Motivation Scale. Studiens resultat visade bland annat att kvinnliga studenter hade en högre nivå utav yttre motivation än manliga studenter. Resultatet visade inga könsskillnader inom inre motivation och amotivation. Resultatet påvisade även att studenter som hade en högre nivå utav yttre motivation samtidigt hade en högre nivå utav inre motivation. Förslag på framtida forskning inom området är att fokusera på studenter inom andra typer av utbildningar och utbildningsnivåer.

Bakgrund och problem: Självbestämmanderätt är en grundprincip i socialtjänstlagen och ska genomsyra allt socialt arbete. Socialtjänstlagen gör ingen skillnad på friska eller sjuka människor, vilket kan skapa dilemman för biståndshandläggare vid behovsbedömning. Syfte och frågeställningar: Studiens syfte är att uppnå en förståelse kring hur bistånds-handläggare arbetar med självbestämmanderätt och inflytande vid behovsbedömning. Studiens frågeställningar är följande: Hur ser biståndshandläggare på äldres självbestämmanderätt när det finns en bristande insikt i de egna behoven? Hur hanterar biståndshandläggare anhörigas inflytande? Metod: Studien är influerad av en kvalitativ och kvantitativ metodblandning och består av en vinjett besvarad av 24 biståndshandläggare, samtliga arbetande utifrån socialtjänstlagen inriktat mot äldreomsorg. Det insamlade empirimaterialet från biståndshandläggarna har bearbetats genom en tematisk analys. Resultat och slutsatser: Resultatet visar att biståndshandläggare menar att den äldre har självbestämmanderätt trots bristande insikt i sina egna behov. Biståndshandläggarnas utsagor visar att den moraliska aspekten att göra gott för den äldre väger tyngre än dennes självbestämmanderätt. Resultatet visar att anhöriga har ett stort inflytande och spelar en viktig roll vid behovsbedömning.