<p>This research focused on developing adaptable models and protocols for early warning systems for forecasting plant diseases and datasets. It compared the performance of deep learning models in predicting soybean rust disease outbreaks using three years of public epidemiological data and gridded weather data. The models selected were a dense network and a Long Short-Term Memory (LSTM) network. The objectives included evaluating the effectiveness of small citizen science datasets and gridded meteorological weather in sequential forecasting, assessing the ideal window size and important inputs, and exploring the generalizability of the model protocol and models to other diseases. The model protocol was developed using a soybean rust dataset. Both the dense and the LSTM networks produced accuracies of over 90% during optimization. When tested for forecasting, both networks could forecast with an accuracy of 85% or higher over various window sizes. Experiments on window size indicated a minimum input of 8 -11 days. Generalizability was demonstrated by applying the same protocol to a southern corn rust dataset, resulting in 87.8% accuracy. In addition, transfer learning and pre-trained models were tested. Direct transfer learning between disease was not successful, while pre training models resulted both positive and negative results. Preliminary results are reported for building generalizable disease models using epidemiological and weather data that researchers could apply to generate forecasts for new diseases and locations.</p>