This study examined scientific evidence of animal-supported work in connection with the therapeutic relationship. The study aimed to investigate whether animal-supported work has any impact on the therapeutic relationship. The study also aimed to examine in what way animal-supported work impacts the therapeutic relationship and whether the effects could be explained by relevant theories. Literature review was chosen as the method of study to fulfil the objectives of this study and data was analysed through thematic analysis. The data used in this study was found in articles through a structured search of the databases PubMed and Psycinfo. In summary, the study found that there is scientific evidence that animal-supported work does impact the therapeutic relationship. The study also found that evidence suggest that animal-supported work impacts the therapeutic relationship in many ways, most of which are positive. The study found that one viable way of explaining the effects of animal-supported work is through the neurobiological theory of oxytocin. The effects could also be explained by the developmental psychological attachment theory. The result of this study points to a need for further research of the effects of animal-supported work on the therapeutic relationship.