- About
-
The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 91 to 93 of 93 (0.024 seconds)| 91 |
Podještědská obec Hradčany v příběhu soudobých dějin / Municipality of Hradčany in Podještědí in the story of contemporary historyHavelka, Jan January 2017 (has links)
This master's thesis follows the author's previous bachelor thesis Village Hradčany in Podještědí at Contemporary History 1914 -1948. Using terminology and methods of regional history and microhistory it accents exploring contemporary history of whole commune and municipality Hradčany with all of its historical villages. It will deal comprehensively with cultural-historical and political-historical problems and phenomena of the of the second half of the 20th century, beginning with the communist rise of power in 1948 , continuing by demise of traditional rural economy in the fifties. But it will also mention the extinction of commune Hradčany itself and its connecting to the bigger commune of socialist type in seventies and developement of socialist rural society. Due to comparing the local archive sources with sources from other surrounding settlements the work should produce a synthetical historical source, which could be taken as a general picture of history of settlements in the region. The whole work is based primarily on archive and oral-history research, interviews with the oldest settlers, collection of photographic sources and written documents as memories.
|
| 92 |
"In the Ghetto, Life no easy for we": The Construction and Negotiation of Identity in Ajegunle Raga.Ogunbowale, Mopelolade Oreoluwa 03 July 2012 (has links)
This thesis is an investigation into the historical evolution of Ajegunle Raga, a reggae form developed within an urban ghetto in Lagos called Ajegunle and the construction and negotiation of identities therein. The research further argues that Ajegunle Raga is a home-grown oppositional music subculture that draws inspiration from diasporic musical subcultures like Reggae and Hip Hop but retains a genuine representation of Ajegunle in its tales of survival, poverty, marginalization and expressions of creativity within the ambience of the music.
|
| 93 |
SCF cdc4 regulates msn2 and msn4 dependent gene expression to counteract hog1 induced lethalityVendrell Arasa, Alexandre 16 January 2009 (has links)
L'activació sostinguda de Hog1 porta a una inhibició del creixement cel·lular. En aquest treball, hem observat que el fenotip de letalitat causat per l'activació sostinguda de Hog1 és parcialment inhibida per la mutació del complexe SCFCDC4. La inhibició de la mort causada per l'activació sostinguda de Hog1 depèn de la via d'extensió de la vida. Quan Hog1 s'activa de manera sostinguda, la mutació al complexe SCFCDC4 fa que augmenti l'expressió gènica depenent de Msn2 i Msn4 que condueix a una sobreexpressió del gen PNC1 i a una hiperactivació de la deacetilassa Sir2. La hiperactivació de Sir2 és capaç d'inhibir la mort causada per l'activació sostinguda de Hog1. També hem observat que la mort cel·lular causada per l'activació sostinguda de Hog1 és deguda a una inducció d'apoptosi. L'apoptosi induïda per Hog1 és inhibida per la mutació al complexe SCFCDC4. Per tant, la via d'extensió de la vida és capaç de prevenir l'apoptosi a través d'un mecanisme desconegut. / Sustained Hog1 activation leads to an inhibition of cell growth. In this work, we have observed that the lethal phenotype caused by sustained Hog1 activation is prevented by SCFCDC4 mutants. The prevention of Hog1-induced cell death by SCFCDC4 mutation depends on the lifespan extension pathway. Upon sustained Hog1 activation, SCFCDC4 mutation increases Msn2 and Msn4 dependent gene expression that leads to a PNC1 overexpression and a Sir2 deacetylase hyperactivation. Then, hyperactivation of Sir2 is able to prevent cell death caused by sustained Hog1 activation. We have also observed that cell death upon sustained Hog1 activation is due to an induction of apoptosis. The apoptosis induced by Hog1 is decreased by SCFCDC4 mutation. Therefore, lifespan extension pathway is able to prevent apoptosis by an unknown mechanism.
|
Page generated in 0.0424 seconds