A continued increase in government regulations for fuel economy and emissions has driven automakers and suppliers to take a large interest in hybridizing vehicles to help them achieve the new requirements. This increased vehicle electrification has resulted in unconventional vehicle cooling requirements. Electrified vehicle batteries and motors operate under different temperature regimes and cooling loads change drastically with driving styles and conditions. A variable-load cooling system was designed, implemented and tested on the Mississippi State University EcoCAR extended-range electric vehicle (E-REV). This system, utilizing variable flow pumps and variable speed fans, was shown to successfully cool the electronic components under the worst-case design conditions, while providing low energy consumption under normal conditions. When compared to a baseline system utilizing no variable duty cycle components, the variable cooling power system reduced energy consumption during testing both on-road at MSU’s facility and on-road at General Motors proving grounds in Michigan.