The aim of our study is to ascertain whether a hanging suspension fluorescentlamp for a private home environment is going to be attractive for a largeaudience. We want to open up for new uses of fluorescent lamps as lightsources.The main approach in this work is how to design a fixture with fluorescentlamps as a light source that will meet the requirements and requests of thehome environment could look like. At the same time we want to make a newimpression of how a fluorescent light source.Primarily we used a quantitative method, but this was rejected after a pilotstudy. Instead we used a qualitatively based method in the sense that weconducted a group interview as well as individual interviews.Based on data from the interviews and our preliminary work a prototype wasbuilt. This prototype is a fluorescent fixture equipped with 2x14W T5fluorescent lamps, dimmed separately. The shape can be described as a soft,organic elongated oval. The luminary screen is made of rice paper, which givesa soft and pleasant light transmission. Access to the interior and electronics isprovided via the open ends of the screen, which is concealed by two endcapsules in plastic. The luminary is a hanging suspension via two wires fromthe ceiling, down to a metal bracket with the same curvature as the luminaryscreen. This metal bracket is then attached to the fixture with wires attached tothe interior, which in turn holds the screen.Our main conclusion is that you can create a very attractive light fitting for theprivate home market. In addition, we concluded that in order to achievesufficient data in a quantitative based study you need more time than what ispermitted within the timeframe of our work. We believe more in the idea offirst develop a good and functional prototype and then ask a panel ofprospective customers what they think about it. Their response will thereafterbe worked in to the final product.KeywordsFluorescent Luminary, fluorescent lamps, fluorescent lamps and luminaries,market, rice paper, dimmableAbstractThe aim of our study is to ascertain whether a hanging suspension fluorescentlamp for a private home environment is going to be attractive for a largeaudience. We want to open up for new uses of fluorescent lamps as lightsources.The main approach in this work is how to design a fixture with fluorescentlamps as a light source that will meet the requirements and requests of thehome environment could look like. At the same time we want to make a newimpression of how a fluorescent light source.Primarily we used a quantitative method, but this was rejected after a pilotstudy. Instead we used a qualitatively based method in the sense that weconducted a group interview as well as individual interviews.Based on data from the interviews and our preliminary work a prototype wasbuilt. This prototype is a fluorescent fixture equipped with 2x14W T5fluorescent lamps, dimmed separately. The shape can be described as a soft,organic elongated oval. The luminary screen is made of rice paper, which givesa soft and pleasant light transmission. Access to the interior and electronics isprovided via the open ends of the screen, which is concealed by two endcapsules in plastic. The luminary is a hanging suspension via two wires fromthe ceiling, down to a metal bracket with the same curvature as the luminaryscreen. This metal bracket is then attached to the fixture with wires attached tothe interior, which in turn holds the screen.Our main conclusion is that you can create a very attractive light fitting for theprivate home market. In addition, we concluded that in order to achievesufficient data in a quantitative based study you need more time than what ispermitted within the timeframe of our work. We believe more in the idea offirst develop a good and functional prototype and then ask a panel ofprospective customers what they think about it. Their response will thereafterbe worked in to the final product. Keywords Fluorescent Luminary, fluorescent lamps, fluorescent lamps and luminaries,market, rice paper, dimmable

<p>The aim of our study is to ascertain whether a hanging suspension fluorescentlamp for a private home environment is going to be attractive for a largeaudience. We want to open up for new uses of fluorescent lamps as lightsources.The main approach in this work is how to design a fixture with fluorescentlamps as a light source that will meet the requirements and requests of thehome environment could look like. At the same time we want to make a newimpression of how a fluorescent light source.Primarily we used a quantitative method, but this was rejected after a pilotstudy. Instead we used a qualitatively based method in the sense that weconducted a group interview as well as individual interviews.Based on data from the interviews and our preliminary work a prototype wasbuilt. This prototype is a fluorescent fixture equipped with 2x14W T5fluorescent lamps, dimmed separately. The shape can be described as a soft,organic elongated oval. The luminary screen is made of rice paper, which givesa soft and pleasant light transmission. Access to the interior and electronics isprovided via the open ends of the screen, which is concealed by two endcapsules in plastic. The luminary is a hanging suspension via two wires fromthe ceiling, down to a metal bracket with the same curvature as the luminaryscreen. This metal bracket is then attached to the fixture with wires attached tothe interior, which in turn holds the screen.Our main conclusion is that you can create a very attractive light fitting for theprivate home market. In addition, we concluded that in order to achievesufficient data in a quantitative based study you need more time than what ispermitted within the timeframe of our work. We believe more in the idea offirst develop a good and functional prototype and then ask a panel ofprospective customers what they think about it. Their response will thereafterbe worked in to the final product.KeywordsFluorescent Luminary, fluorescent lamps, fluorescent lamps and luminaries,market, rice paper, dimmableAbstractThe aim of our study is to ascertain whether a hanging suspension fluorescentlamp for a private home environment is going to be attractive for a largeaudience. We want to open up for new uses of fluorescent lamps as lightsources.The main approach in this work is how to design a fixture with fluorescentlamps as a light source that will meet the requirements and requests of thehome environment could look like. At the same time we want to make a newimpression of how a fluorescent light source.Primarily we used a quantitative method, but this was rejected after a pilotstudy. Instead we used a qualitatively based method in the sense that weconducted a group interview as well as individual interviews.Based on data from the interviews and our preliminary work a prototype wasbuilt. This prototype is a fluorescent fixture equipped with 2x14W T5fluorescent lamps, dimmed separately. The shape can be described as a soft,organic elongated oval. The luminary screen is made of rice paper, which givesa soft and pleasant light transmission. Access to the interior and electronics isprovided via the open ends of the screen, which is concealed by two endcapsules in plastic. The luminary is a hanging suspension via two wires fromthe ceiling, down to a metal bracket with the same curvature as the luminaryscreen. This metal bracket is then attached to the fixture with wires attached tothe interior, which in turn holds the screen.Our main conclusion is that you can create a very attractive light fitting for theprivate home market. In addition, we concluded that in order to achievesufficient data in a quantitative based study you need more time than what ispermitted within the timeframe of our work. We believe more in the idea offirst develop a good and functional prototype and then ask a panel ofprospective customers what they think about it. Their response will thereafterbe worked in to the final product.</p><p>Keywords</p><p>Fluorescent Luminary, fluorescent lamps, fluorescent lamps and luminaries,market, rice paper, dimmable</p>

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published_or_final_version / abstract / Chemistry / Doctoral / Doctor of Philosophy

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This thesis describes efforts at the interface of chemistry and neuroscience to design and characterize fluorescent probes capable of tracing neurotransmitters from individual release sites in brain tissue. As part of the Fluorescent False Neurotransmitters (FFNs) program, small organic fluorophores have been developed that undergo uptake into specific presynaptic release sites and synaptic vesicles by utilizing the native protein machinery, which can then be released during neuronal firing. The most advanced generation of FFNs are pH-sensitive, and display an increase in fluorescence when released from the acidic vesicular lumen into the extracellular space, called a “FFN Flash.” In Chapter 2, the utility of the dopamine-selective and pH-sensitive functionality of FFN102 to study the mechanisms that regulate changes in pre-synaptic plasticity, a critical component of neurotransmission was explored. This included using the FFN flash to quantitatively trace dopamine release, changes in the release probability of individual release sites, and changes in vesicular loading that can affect quantal size. The second goal of this thesis research, as detailed in Chapters 3 and 4, sought to expand the substrate scope of the FFN program to neurotransmitter systems other than dopamine. Described in Chapter 3, is the identification of a fluorescent phenylpyridinium, APP+, with excellent labeling for dopamine, norepinephrine, and serotonin neurons, however, the properties of the probe were found to be ill-suited for measuring neurotransmitter release. As a result, it was concluded that this class of compounds was not suitable for generating viable FFN leads. In contrast, Chapter 4 highlights the design, synthesis, and screening towards generating the novel noradrenergic-specific FFN, FFN270. This probe was further tested for application in acute murine brain slices where it labeled noradrenergic neurons, and was demonstrated to release upon stimulation. This chapter also describes the application of this compound in a series of in vivo experiments, where the ability to measure norepinephrine release from individual release sites was demonstrated in a living animal for the first time. This work opens the possibility for many exciting future FFN experiments studying the presynaptic regulation of neurotransmission in vivo.