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Development of a Phantom Tissue for Blood Perfusion Measurements and Noninvasive Blood Perfusion Estimation in Living TissueMudaliar, Ashvinikumar 17 April 2007 (has links)
A convenient method for testing and calibrating surface perfusion sensors has been developed. A phantom tissue model is used to mimic the non-directional blood flow of tissue perfusion. A computational fluid dynamics (CFD) model was constructed in Fluent to design the phantom tissue and validate the experimental results. The phantom perfusion system was used with a perfusion sensor based on the clearance of thermal energy. A heat flux gage measures the heat flux response of tissue when a thermal event (convective cooling) is applied. The blood perfusion and contact resistance are estimated by a parameter estimation code. From the experimental and analytical results, it was concluded that the probe displayed good measurement repeatability and sensitivity. The experimental perfusion measurements in the tissue were in good agreement with those of the CFD models and demonstrated the value of phantom tissue system.
This simple, cost effective, and noninvasive convective blood perfusion system was then tested in animal models. The perfusion system was evaluated for repeatability and sensitivity using isolated rat liver and exposed rat kidney tests. Perfusion in the isolated liver tests was varied by controlling the flow of the perfusate into the liver, and the perfusion in the exposed kidney tests was varied by temporarily occluding blood flow through the renal artery and vein. The perfusion estimated by the convective perfusion probe was in good agreement with that of the metered flow of perfusate into the liver model. The liver tests indicated that the probe can be used to detect small changes in perfusion (0.005 ml/ml/s). The probe qualitatively tracked the changes in the perfusion in kidney model due to occlusion of the renal artery and vein. / Ph. D.
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High Temperature Heat Flux Measurement: Sensor Design, Calibration, and ApplicationsPullins, Clayton Anthony 27 May 2011 (has links)
This effort is focused on the design, calibration, and implementation of a high temperature heat flux sensor for thermal systems research and testing. The High Temperature Heat Flux Sensor (HTHFS) was designed to survive in the harsh thermal environments typically encountered in hypersonic flight, combustion and propulsion research, and large-scale fire testing. The sensor is capable of continuous use at temperatures up to 1000 â ¦C. Two methods for steady-state calibration of the HTHFS at elevated temperatures have been developed as a result of this research. The first method employs a water-cooled heat flux sensor as a reference standard for the calibration. The second method utilizes a blackbody radiant source and a NIST calibrated optical pyrometer as the calibration standard. The HTHFS calibration results obtained from both methods compare favorably with the theoretical sensitivity versus temperature model.
Implementation of the HTHFS in several types of transient thermal testing scenarios is also demonstrated herein. A new data processing technique is used to interpret the measurements made by the HTHFS. The Hybrid Heat Flux (HHF) method accounts for the heat flow through the sensor and the heat storage in the sensor, and thus renders the HTHFS virtually insensitive to the material on which it is mounted. The calibrated output of the HTHFS versus temperature ensures accuracy in the measurements made by the sensor at high operating temperatures. / Ph. D.
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Large eddy simulation of subsonic mixing layersSheen, Shaw-Ching 26 October 2005 (has links)
Large eddy simulation is used to study the large-scale structures in a low subsonic mixing layer and their breakdown to small scales. For 3-D simulations, different finite-difference and pseudo-spectral schemes are tested. The (2, 4) MacCormack Scheme developed by Gottlieb and Turkel (1976) shows the best overall performance. It is very fast and supplies enough but not excessive artificial dissipation. Though slower than MacCormack scheme, the pseudo-spectral method has its advantage: high resolution of the high-wavenumber range when adequate de-aliasing scheme is used. When efficient fast Fourier transform routines are available, this method can be a very good alternative to the MacCormack scheme. Most of the simulations use a modified Smagorinsky-type model (Erlabacher et al. 1992). The effect of different models and model constants is also studied. It is found that the two subgrid-scale (SGS) models, the Smagorinsky model and the linear combination model (Bardina et al. 1983), show significant difference even at the low wavenumber range of the spectra.
In the study of three-dimensional subsonic temporal mixing layers, it is found that the streamwise vortex tubes play an important role in the transition process. The vortex interaction of the streamwise vortex tubes and undulated spanwise vortex structures proves to be the dominant mechanism in the development of three-dimensionality and the subsequent generation of small-scale motions. In the absence of pairing of the spanwise vortex tubes, this vortex interaction causes uneven distribution of vorticity along the span of the spanwise vortex tubes and the breaking of the large structures. Following the breaking of the spanwise vortex tubes, the secondary streamwise vortex tubes become the dominant vortex structures.
In the case involving pairing, it is found that the relative motion of the spanwise vortex tubes in the pre-pairing process creates much stronger strain rate field between the pairing vortex tubes than the case without pairing. The stronger strain rate field leads to the formation of streamwise vortex tubes with very high vorticity and low induced pressure. This also leads to much stronger vortex interaction between the spanwise and streamwise vortex tubes due to the increased strength of the streamwise vortex tubes. / Ph. D.
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Momentum - Transformation of Movement into ArchitectureKohler, Xandra 14 October 2002 (has links)
The Thesis discusses ways of transforming motion, found in bodies, into architecture, by clarifying complex structural superimpositions. It addresses the relationship between movement found in natural bodies and urban structures and its parallels in architecture in relation to time and external forces. Transformational motion can be found in every element.
The thesis defines and structures site-specific parameters, and transforms them into architectonic guidelines. Through the integration of a specific program, these guidelines are translated into a school of performing art. / Master of Architecture
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Carbon Monoxide Generation in a Compartment With a Doorway During a FireMcKay, Christopher A. 18 February 2002 (has links)
The study of the products of combustion continues to have real-world relevance since the primary cause of death in building fires is smoke inhalation, with the majority of deaths from carbon monoxide, CO, poisoning. An experimental study was conducted to examine upper-layer structure plus provide an initial characterization of a new compartment with a doorway. An additional study of the relationship between heat flux from external burning in a hallway and levels of carbon monoxide is also reported.
Tests were conducted in a new ½ scale ISO compartment with a fully scaled doorway, using n-hexane pool fires within the center of the compartment. Upper-layer sampling at eight locations in the compartment has shown that the compartment upper-layer is relatively uniform in species mole fractions, yields, and temperature. Sampling in the front upper-layer of the compartment was performed for a series of experiments where the equivalence ratio was varied. Temperatures, species mole fractions, species yields, and doorway flows were found to have definite trends, which agreed with previous studies.
The heat flux study utilized a reduced scale compartment with a separate inlet and an exit vent, which connected into the side of an attached hallway, forming an L-shape. For two cases of a deep and shallow hallway upper-layer a direct relationship between flames in the upper-layer and total heat flux was measured. High heat flux was found to only denote those areas were flames are present and is not related to the levels of CO present or oxidized in the hallway. / Master of Science
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Development of the Passive Perfusion Probe for Non-Invasive Blood Perfusion MeasurementRicketts, Patricia Lynn 06 July 2007 (has links)
A non-invasive blood perfusion system has been developed and tested in a phantom tissue and an animal model. The system uses a small sensor with a laminated flat thermocouple to measure the heat transfer response to an arbitrary thermal event (convective or conductive) imposed on the tissue surface. Blood perfusion and contact resistance are estimated by comparing heat flux data with a mathematical model of the tissue. The perfusion system was evaluated for repeatability and sensitivity using both a phantom tissue test stand and exposed rat liver tests. Perfusion in the phantom tissue tests was varied by controlling the flow of water into the phantom tissue test section, and the perfusion in the exposed liver tests was varied by temporarily occluding blood flow through the portal vein. The phantom tissue tests indicated that the probe can be used to detect small changes in perfusion (0.009 ml/ml/s). The probe qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein. / Master of Science
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Convection Calibration of Schmidt-Boelter Heat Flux Gages in Shear and Stagnation Air FlowHoffie, Andreas Frank 23 May 2007 (has links)
This work reports the convection calibration of Schmidt-Boelter heat flux gages in shear and stagnation air flow. The gages were provided by Sandia National Laboratories and included two one-inch diameter and two one-and-one-half-inch diameter Schmidt-Boelter heat flux gages. In order to calibrate the sensors a convection calibration facility has been designed, including a shear test stand, a stagnation test stand, an air heater and a data acquisition system. The current physical model for a combined radiation and convection heat transfer environment uses an additional thermal resistance around the heat flux gage. This model clearly predicts a non-linear dependency of the gage sensitivity over a range of heat transfer coefficients. A major scope of this work was to experimentally verify the relation found by the model assumptions. Since the actual heat sink temperature is not known and cannot be measured, three different cases have been examined resulting in three different sensitivities for one pressure value, which is the gage sensitivity for the not cooled case and the gage sensitivity for the cooled case, based on the plate temperature or on the cooling water temperature. All of the measured sensitivities for shear as well as for stagnation flow fit well in the theory and show the non-linear decay for increasing heat transfer coefficient values. However, the obtained data shows an offset in the intersection with the sensitivity at zero heat transfer coefficient. This offset might arise from different radiation calibration techniques and different surface coatings of test gage and reference standard. / Master of Science
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Design and Calibration of a Novel High Temperature Heat Flux SensorRaphael-Mabel, Sujay Anand 20 April 2005 (has links)
Heat flux gages are important in applications where measurement of the transfer of energy is more important than measurement of the temperature itself. There is a need for a heat flux sensor that can perform reliably for long periods of time in high temperature and high heat flux environment. The primary objective is to design and build a heat flux sensor that is capable of operating for extended periods of time in a high heat flux and high temperature environment. A High Temperature Heat Flux Sensor (HTHFS) was made by connecting 10 brass and steel thermocouple junctions in a thermopile circuit. This gage does not have a separate thermal resistance layer making it easier to fabricate. The HTHFS was calibrated in a custom-made convection calibration facility using a commercial Heat Flux Microsensor (HFM) as the calibration standard.
The measured sensitivity of the HTHFS was 20.4 ±2.0ìV/(W/cm2). The measured sensitivity value matched with the theoretically calculated value of 20.5 ìV/(W/cm2). The average sensitivity of the HTHFS prototype was one-fifth of the sensitivity of a commercially available HFM. Better ways of mounting the HTHFS in the calibration stand have been recommended for future tests on the HTHFS for better testing. The HTHFS has the potential to be made into a microsensor with thousands of junctions added together in a thermopile circuit. This could lead to a heat flux sensor that could generate large signals (~few mV) and also be capable of operating in high heat flux and high temperature conditions. / Master of Science
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Desing of the high Pressure HIgh temperature annuLUS flow (PHILUS) FacilityKarabacak, Ali Haydar 17 June 2022 (has links)
Critical heat flux (CHF) and post-CHF are two critical phenomena in light water-cooled nuclear power plants regarding safety. Even though the general trends of CHF and post- CHF are known, the exact mechanisms are still unknown. To better understand CHF and post-CHF, experimental flow boiling facilities are constructed around the world. However, these facilities are limited in their experimental conditions and spatial resolution necessary to advance our understanding of two-phase heat transfer. Previous rod surface measurements were collected with thermocouples to measure CHF location and temperature excursion, yet thermocouples provide limited spatial resolution, which leads to significant uncertainties in the CHF prediction. On the other hand, optical fiber temperature sensors can measure the temperature and the CHF propagation with high spatial resolution. Also, the capability of the optical fiber at high temperatures has been proven in previous studies. The current study aims to apply optical fiber at high-pressure and high mass fluxes. The high-Pressure HIgh-temperature annuLUS flow (PHILUS) facility was designed to provide desired working conditions in the test section that uses optical fiber temperature sensors. The PHILUS test section has a length of 1320 mm, with 1000 mm of heated length. The working conditions of the PHILUS are up to 18 MPa, temperatures up to 357◦C, and coolant mass flux from 500 to 3700 kg/m2s. The main components of the loop are a steam separator, two heat exchangers (a condenser and a cooler), a bladder-type accumulator, two bypass lines, and a high-pressure pump. Coolant-Boiling in Rod Arrays-Two Fluids (COBRA-TF) code was used to design the CHF and post-CHF experiments to be performed at the PHILUS facility. / Master of Science / A nuclear power plant produces heat which is transferred from the reactor core through the coolant. The coolant water flows through the reactor core to safely transport the heat that ultimately is used to produce electrical energy. If the balance between the power produced by fission and the energy removed by the coolant is changed, it can lead to potential damage to the reactor core. The maximum heat transfer rate occurs at the point where a vapor blanket covers the surface of the fuel cladding. At this point, known as Critical Heat Flux (CHF), the surface temperature drastically increases. To better understand and better predict the CHF, experimental facilities are needed. Even though there are several facilities worldwide, most of them have limited working conditions and measurement capabilities. Past experiments used thermocouples to measure the surface temperature with a very small spatial resolution, which causes very large uncertainties in the CHF and post-CHF predictions. On the other hand, optical fiber sensors can be used to measure temperature with very high spatial resolution. The high-Pressure HIgh-temperature annuLUS flow (PHILUS) facility was designed in this work to apply optical fibers in the measurement of the rod surface temperature and simulations were performed to show its advantages. The working conditions of the PHILUS are comparable to commercial pressurized water reactors.
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MHD Stability and Scenario Development of Negative Triangularity Plasmas in DIII-DBoyes, William Samuel January 2024 (has links)
Experiments on the DIII-D device in the negative triangularity (NT) regime of tokamak operation demonstrate core conditions that offer advantageous stability properties. Long duration, stationary discharges in this scenario maintain performance metrics that scale to viable reactor gain. Deleterious global modes of toroidal mode number n=1 are infrequent in these plasmas, which operate free of core instability cycles that can kick off global instabilities.
These plasmas operate free of edge instability cycles that would damage reactor components, as do all strongly shaped NT plasmas. Reproducible access to high-power stationary states was developed at two values of q95, the edge magnetic winding number or “safety factor”. Core MHD instabilities manifest in one form of internal ideal mode, the quasi-interchange mode (QI), found to be consistent with modeling of the profiles and parameter space in which NT operates. The GATO and DCON ideal MHD codes are used to characterize the limits to normalized pressure in NT, finding global kink modes with strong poloidal harmonic m=1,2 components at normalized plasma pressure βN=3-3.5. Limits to β_N are predicted to be mostly insensitive to plasma boundary shape in NT and similar at both q95 values obtained in experiments. Average triangularity is shown to affect ideal limits, when modified at the outer midplane.
A similar result is obtained with the RDCON resistive MHD code, which is used to characterize the stability to resistive “tearing modes”. Experimental NT equilibria and equilibria across shape scans were investigated. Only outer midplane modifications affected tearing calculations. Ideal kink modeling and experimental observations of sporadic QI mode provide an explanation for current diffusion not predicted by neoclassical theory. This effect is found in experiments at q95=3, analyzed with the ONETWO transport code’s facility to evolve magnetic flux over a discharge consistently with measured profiles and reconstructed magnetic flux surfaces. This result is compared with GATO calculations and ONETWO flux diffusion analysis of a conventional shape, ITER baseline demonstration discharge that is shown to have an intrinsically 3D core. Radiation from accumulated plasma impurities seems to alter the core q profile.
This makes unstable a QI mode that spurs formation of a helical core, sustained by anomalous magnetic flux diffusion. NT experiments at q95=4 are limited in energy confinement by poor fast ion confinement, as a result of nondisruptive core 3/2 tearing modes. Analysis with ONETWO shows agreement with neoclassical flux diffusion predictions in these cases, corresponding to a removal of core instabilities and elevation of minimum safety factor values qmin to unity. This understanding of the core MHD, performance, and operational limits of NT scenarios in DIII-D advances the development of negative triangularity scenarios and informs the core phenomena observed in experiments spanning the regime.
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