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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

A matched case control study of the nutritional status of newly diagnosed tuberculosis patients and tuberculosis free contacts in Delft, Western Cape

Lombardo, Candice Clarissa January 2011 (has links)
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UnhideWhenUsed="false" QFormat="true" Name="Subtle Reference" /> <w:LsdException Locked="false" Priority="32" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Reference" /> <w:LsdException Locked="false" Priority="33" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Book Title" /> <w:LsdException Locked="false" Priority="37" Name="Bibliography" /> <w:LsdException Locked="false" Priority="39" QFormat="true" Name="TOC Heading" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal" / mso-tstyle-rowband-size:0 / mso-tstyle-colband-size:0 / mso-style-noshow:yes / mso-style-priority:99 / mso-style-parent:"" / mso-padding-alt:0cm 5.4pt 0cm 5.4pt / mso-para-margin-top:0cm / mso-para-margin-right:0cm / mso-para-margin-bottom:10.0pt / mso-para-margin-left:0cm / line-height:115% / mso-pagination:widow-orphan / font-size:11.0pt / font-family:"Calibri","sans-serif" / mso-ascii-font-family:Calibri / mso-ascii-theme-font:minor-latin / mso-hansi-font-family:Calibri / mso-hansi-theme-font:minor-latin / mso-bidi-font-family:"Times New Roman" / mso-bidi-theme-font:minor-bidi / mso-ansi-language:EN-US / mso-fareast-language:EN-US / } </style> <![endif]--><b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Background</span></b><span lang="EN-GB">: Malnutrition is a risk factor for the development of pulmonary tuberculosis (TB) and may be responsible for the premature deaths of patients with active disease. An adequate nutritional status may therefore be protective in delaying the onset from latent infection to active disease. In South Africa, very little data is available on the nutritional status of adults who present with tuberculosis. This study therefore aims to compare the nutritional status of newly diagnosed pulmonary tuberculosis patients with TB-free controls.</span> <b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Study population &amp / Design</span></b><span lang="EN-GB">: This is a community based case-control study. Forty-three newly diagnosed pulmonary tuberculosis patients were recruited as cases and matched according to age, gender and race to 43 TB-free close contacts. HIV positive subjects were excluded from the study.</span> <b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Methods</span></b><span lang="EN-GB">: Each participant was interviewed and completed a structured questionnaire to obtain demographic information. Weight was measured to the nearest 0.1kg and height to the nearest 1mm. A 24-hr dietary recall method was used to obtain dietary information. Biochemical analysis was carried out to measure&nbsp / concentrations of transferrin, albumin, CRP, ferritin, zinc, copper, vitamin A and E.</span> <b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Results</span></b><span lang="EN-GB">: The median Body Mass Index (BMI) for cases was 18.80kg/m&sup2 / (IQR 14.35, 32.11) and TB-free contacts 21.17 kg/m&sup2 / (IQR 16.75, 34.98) with a significant difference between the groups of p=0.001. There was significant difference in weight (p=0.002) and MUAC (p=0.000) between groups. No significant difference in dietary intake of energy (KJ) (p=0.695), protein (p=0.804), CHO (p=0.801) and fat ( p=0.796) was found between groups. There was a statistically significant increase in ferritin (p=0.000) and C-reactive protein (CRP) (p=0.000) in TB patients, while albumin (p=0.000), serum zinc (p=0.000) and serum vitamin A (p=0.000) were statistically significantly lower among cases.</span> <b style="mso-bidi-font-weight:normal"><span lang="EN-GB">Conclusion</span></b><span lang="EN-GB">: There was no significant difference in the macronutrient intake of TB cases and TB-free contacts, although a significant difference was seen in BMI, MUAC and weight between groups, with all these parameters being lower in TB patients. Ferritin and CRP levels were markedly increased in TB cases while serum zinc, vitamin A and albumin are all significantly lower in&nbsp / TB patients than TB free contacts.</span> <b style="mso-bidi-font-weight:normal"><span lang="EN-GB">&nbsp / </span></b></p> <p>&nbsp / </p>
2

A matched case control study of the nutritional status of newly diagnosed tuberculosis patients and tuberculosis free contacts in Delft, Western Cape

Lombardo, Candice Clarissa January 2011 (has links)
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mso-ascii-font-family:Calibri / mso-ascii-theme-font:minor-latin / mso-hansi-font-family:Calibri / mso-hansi-theme-font:minor-latin / mso-bidi-font-family:"Times New Roman" / mso-bidi-theme-font:minor-bidi / mso-ansi-language:EN-US / mso-fareast-language:EN-US / } </style> <![endif]--><b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Background</span></b><span lang="EN-GB">: Malnutrition is a risk factor for the development of pulmonary tuberculosis (TB) and may be responsible for the premature deaths of patients with active disease. An adequate nutritional status may therefore be protective in delaying the onset from latent infection to active disease. In South Africa, very little data is available on the nutritional status of adults who present with tuberculosis. This study therefore aims to compare the nutritional status of newly diagnosed pulmonary tuberculosis patients with TB-free controls.</span> <b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Study population &amp / Design</span></b><span lang="EN-GB">: This is a community based case-control study. Forty-three newly diagnosed pulmonary tuberculosis patients were recruited as cases and matched according to age, gender and race to 43 TB-free close contacts. HIV positive subjects were excluded from the study.</span> <b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Methods</span></b><span lang="EN-GB">: Each participant was interviewed and completed a structured questionnaire to obtain demographic information. Weight was measured to the nearest 0.1kg and height to the nearest 1mm. A 24-hr dietary recall method was used to obtain dietary information. Biochemical analysis was carried out to measure&nbsp / concentrations of transferrin, albumin, CRP, ferritin, zinc, copper, vitamin A and E.</span> <b style="mso-bidi-font-weight: normal"><span lang="EN-GB">Results</span></b><span lang="EN-GB">: The median Body Mass Index (BMI) for cases was 18.80kg/m&sup2 / (IQR 14.35, 32.11) and TB-free contacts 21.17 kg/m&sup2 / (IQR 16.75, 34.98) with a significant difference between the groups of p=0.001. There was significant difference in weight (p=0.002) and MUAC (p=0.000) between groups. No significant difference in dietary intake of energy (KJ) (p=0.695), protein (p=0.804), CHO (p=0.801) and fat ( p=0.796) was found between groups. There was a statistically significant increase in ferritin (p=0.000) and C-reactive protein (CRP) (p=0.000) in TB patients, while albumin (p=0.000), serum zinc (p=0.000) and serum vitamin A (p=0.000) were statistically significantly lower among cases.</span> <b style="mso-bidi-font-weight:normal"><span lang="EN-GB">Conclusion</span></b><span lang="EN-GB">: There was no significant difference in the macronutrient intake of TB cases and TB-free contacts, although a significant difference was seen in BMI, MUAC and weight between groups, with all these parameters being lower in TB patients. Ferritin and CRP levels were markedly increased in TB cases while serum zinc, vitamin A and albumin are all significantly lower in&nbsp / TB patients than TB free contacts.</span> <b style="mso-bidi-font-weight:normal"><span lang="EN-GB">&nbsp / </span></b></p> <p>&nbsp / </p>
3

A matched case control study of the nutritional status of newly diagnosed tuberculosis patients and tuberculosis free contacts in Delft, Western Cape

Lombardo, Candice Clarissa January 2011 (has links)
>Magister Scientiae - MSc / Background: Malnutrition is a risk factor for the development of pulmonary tuberculosis (TB) and may be responsible for the premature deaths of patients with active disease. An adequate nutritional status may therefore be protective in delaying the onset from latent infection to active disease. In South Africa, very little data is available on the nutritional status of adults who present with tuberculosis. This study therefore aims to compare the nutritional status of newly diagnosed pulmonary tuberculosis patients with TB-free controls.Study population & Design: This is a community based case-control study. Forty-three newly diagnosed pulmonary tuberculosis patients were recruited as cases and matched according to age,gender and race to 43 TB-free close contacts. HIV positive subjects were excluded from the study.Methods: Each participant was interviewed and completed a structured questionnaire to obtain demographic information. Weight was measured to the nearest 0.1kg and height to the nearest 1mm. A 24-hr dietary recall method was used to obtain dietary information. Biochemical analysis was carried out to measure concentrations of transferrin, albumin, CRP, ferritin, zinc,copper, vitamin A and E.Results: The median Body Mass Index (BMI) for cases was 18.80kg/m² (IQR 14.35, 32.11) and TB-free contacts 21.17 kg/m² (IQR 16.75, 34.98) with a significant difference between the groups of p=0.001. There was significant difference in weight (p=0.002) and MUAC (p=0.000)between groups. No significant difference in dietary intake of energy (KJ) (p=0.695), protein(p=0.804), CHO (p=0.801) and fat ( p=0.796) was found between groups. There was a statistically significant increase in ferritin (p=0.000) and C-reactive protein (CRP) (p=0.000) in TB patients, while albumin (p=0.000), serum zinc (p=0.000) and serum vitamin A (p=0.000) were statistically significantly lower among cases. Conclusion: There was no significant difference in the macronutrient intake of TB cases and TB-free contacts, although a significant difference was seen in BMI, MUAC and weight between groups, with all these parameters being lower in TB patients. Ferritin and CRP levels were markedly increased in TB cases while serum zinc, vitamin A and albumin are all significantly lower in TB patients than TB free contacts.
4

Development of a new 3D beam finite element with deformable section / Développement d’un nouveau 3D poutre élément fini à section déformable

Gao, Sasa 05 April 2017 (has links)
Le nouvel élément de poutre est une évolution d'un élément de Timoshenko poutre avec un nœud supplémentaire situé à mi-longueur. Ce nœud supplémentaire permet l'introduction de trois composantes supplémentaires de contrainte afin que la loi constitutionnelle 3D complète puisse être utilisée directement. L'élément proposé a été introduit dans un code d'éléments finis dans Matlab et une série d'exemples de linéaires/petites contraintes ont été réalisées et les résultats sont systématiquement comparés avec les valeurs correspondantes des simulations ABAQUS/Standard 3D. Ensuite, la deuxième étape consiste à introduire le comportement orthotrope et à effectuer la validation de déplacements larges / petites contraintes basés sur la formulation Lagrangienne mise à jour. Une série d'analyses numériques est réalisée qui montre que l'élément 3D amélioré fournit une excellente performance numérique. En effet, l'objectif final est d'utiliser les nouveaux éléments de poutre 3D pour modéliser des fils dans une préforme composite textile. A cet effet, la troisième étape consiste à introduire un comportement de contact et à effectuer la validation pour un nouveau contact entre 3D poutres à section rectangulaire. La formulation de contact est dérivée sur la base de formulation de pénalité et de formulation Lagrangian mise à jour utilisant des fonctions de forme physique avec l'effet de cisaillement inclus. Un algorithme de recherche de contact efficace, qui est nécessaire pour déterminer un ensemble actif pour le traitement de contribution de contact, est élaboré. Et une linéarisation constante de la contribution de contact est dérivée et exprimée sous forme de matrice appropriée, qui est facile à utiliser dans l'approximation FEM. Enfin, on présente quelques exemples numériques qui ne sont que des analyses qualitatives du contact et de la vérification de l'exactitude et de l'efficacité de l'élément de 3D poutre proposé. / The new beam element is an evolution of a two nodes Timoshenko beam element with an extra node located at mid-length. That extra node allows the introduction of three extra strain components so that full 3D stress/strain constitutive relations can be used directly. The second step is to introduce the orthotropic behavior and carry out validation for large displacements/small strains based on Updated Lagrangian Formulation. A series of numerical analyses are carried out which shows that the enhanced 3D element provides an excellent numerical performance. Indeed, the final goal is to use the new 3D beam elements to model yarns in a textile composite preform. For this purpose, the third step is introducing contact behavior and carrying out validation for new 3D beam to beam contact with rectangular cross section. The contact formulation is derived on the basis of Penalty Formulation and Updated Lagrangian formulation using physical shape functions with shear effect included. An effective contact search algorithm is elaborated. And a consistent linearization of contact contribution is derived and expressed in suitable matrix form, which is easy to use in FEM approximation. Finally, some numerical examples are presented which are only qualitative analysis of contact and checking the correctness and the effectiveness of the proposed 3D beam element.
5

Das neue Kontaktmodell mit endlicher Reibung in Creo Simulate 3.0 : Theorie und Anwendung ; Vergleich mit dem reibungsfreien und unendlich reibungsbehafteten Kontaktmodell / The New Contact with Finite Friction Feature in Creo Simulate 3.0 : Theory and Application ; Comparison with the Friction-Free and Infinite Friction Contact Models

Jakel, Roland 22 July 2016 (has links) (PDF)
Der Vortrag beschreibt die zugrunde liegende Theorie und die Softwarefunktionalität des in PTC Creo Simulate 3.0 eingeführten Kontaktmodells mit endlicher Reibung und vergleicht dieses mit den bis Creo Simulate 2.0 exklusiv verwendeten Kontaktmodellen (ideal reibungsfrei und unendlich reibungsbehaftet). An zwei Modellbeispielen (ein von zwei Bremsbacken geklemmtes Bremsschwert und ein verschraubtes Schwungrad) wird versucht, die Funktionsweise des neuen Modells zu demonstrieren. Wegen aktueller Qualitätsprobleme der Software wird die Brauchbarkeit der Kontaktmodelle für den Anwender bewertet (Stand Creo 3.0 M080 / Creo 2.0 M200) und umfangreiches Feedback an den Softwarehersteller PTC gegeben. / The presentation describes the underlying theory and software functionality of the finite friction contact model introduced with PTC Creo Simulate 3.0. It is being compared with the friction-free and infinite friction contact model used exclusively until Creo Simulate 2.0. It is being tried to demonstrate the mode of operation of the new model with help of two examples: A brake sword clamped by two brake pads and a bolted flywheel. Because of actual software quality problems, the usability of the contact model for the user is being rated (status Creo 3.0 M080 / Creo 2.0 M200). Furthermore, comprehensive feedback is given to the software developer PTC.
6

Das neue Kontaktmodell mit endlicher Reibung in Creo Simulate 3.0 : Theorie und Anwendung ; Vergleich mit dem reibungsfreien und unendlich reibungsbehafteten Kontaktmodell

Jakel, Roland 22 July 2016 (has links)
Der Vortrag beschreibt die zugrunde liegende Theorie und die Softwarefunktionalität des in PTC Creo Simulate 3.0 eingeführten Kontaktmodells mit endlicher Reibung und vergleicht dieses mit den bis Creo Simulate 2.0 exklusiv verwendeten Kontaktmodellen (ideal reibungsfrei und unendlich reibungsbehaftet). An zwei Modellbeispielen (ein von zwei Bremsbacken geklemmtes Bremsschwert und ein verschraubtes Schwungrad) wird versucht, die Funktionsweise des neuen Modells zu demonstrieren. Wegen aktueller Qualitätsprobleme der Software wird die Brauchbarkeit der Kontaktmodelle für den Anwender bewertet (Stand Creo 3.0 M080 / Creo 2.0 M200) und umfangreiches Feedback an den Softwarehersteller PTC gegeben. / The presentation describes the underlying theory and software functionality of the finite friction contact model introduced with PTC Creo Simulate 3.0. It is being compared with the friction-free and infinite friction contact model used exclusively until Creo Simulate 2.0. It is being tried to demonstrate the mode of operation of the new model with help of two examples: A brake sword clamped by two brake pads and a bolted flywheel. Because of actual software quality problems, the usability of the contact model for the user is being rated (status Creo 3.0 M080 / Creo 2.0 M200). Furthermore, comprehensive feedback is given to the software developer PTC.

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