This dissertation deals with alternative techniques for analysis of genetic information of organisms. The theoretical part presents two different approaches for evaluation of relationship between organisms based on mutual similarity of genetic information contained in their DNA sequences. The first approach is currently standardized phylogenetics analysis of character based records of DNA sequences. Although this approach is computationally expensive due to the need of multiple sequence alignment, it allows evaluation of global and local similarity of DNA sequences. The second approach is represented by techniques for classification of DNA sequences in a form of numerical vectors representing characteristic features of their genetic information. These methods known as „alignment free“ allow fast evaluation of global similarity but cannot evaluate local changes. The new method presented in this dissertation combines the advantages of both approaches. It utilizes numerical representation similar to 1D digital signal, i.e. representation that contains specific trend along x-axis. The experimental part of dissertation deals with design of a set of appropriate tools for genomic signal processing to allow evaluation mutual similarity of taxonomically specific trends. On the basis of the mutual similarity of genomic signals, the classification in the form of dendrogram is applied. It corresponds to phylogenetic trees used in standard phylogenetics.

Mgr. Václav Hrnčíř Mobility of individuals and populations in the prehistoric period. Confrontation of archaeological, ethnological and natural scientific methods. Abstract of dissertation thesis This thesis focuses on the use of natural scientific methods and cross-cultural research to study the mobility of individuals and populations in the prehistoric period and confronts these methods with the results of traditional archaeological approaches. In the first part, the advantages and limits of multiple-tooth strontium isotope analysis are critically assessed. Analysis of published strontium data of more than 1,000 individuals across the world reveals a high degree of variability in childhood mobility patterns between different regions and periods. In the second part, the association between post-marital residence and dwelling size is tested using phylogenetic comparative analysis methods and a global sample of 86 pre-industrial societies. The results confirm that large dwellings are associated with matrilocality (whereas smaller with patrilocality) and suggest that average dwelling size can be used as a material proxy for inferring post-marital residence rules in prehistoric societies. The last part of the thesis combines various types of evidence (archaeological, strontium and ethnographic) to determine...