Deep vein thrombosis (DVT) is a serious postoperative complication and nurses should therefore observe symptoms in an early stage and implement preventive provisions, for example use of graduated compression stockings (GCS). The nurse is also responsible for making sure that ordinate GCS tried and used correctly by the patients. The aim of this study was to investigate the latest research regarding the efficacy of GCS in prevention of postoperative DVT and if there are any incorrectness in usage. And assess guidelines and recommendations for the usage of GCS. Method: Literature review. Search was done in database PubMed and Cinahl. Seven scientific articles were analyzed and national guidelines were summarized. The result indicates that GCS has small effect in preventing DVT in postoperative patients, according to some studies. The national guidelines and recommendation comprehends risk assessment of DVT, and daily observation/control of the legs (skin inspection, the correct fitting, well –informed patient and documentation). Conclusion: The result of this review isn´t concurrent but majority of studies shows minor effect in preventing DVT. For correct usage of GCS recommends that national guidelines should be followed.