The main contens of the thesis is solving a construction-technological project substructure and the upper shell construction of a polyfunctional building in Pardubice. Excavation and foundation work are done in section A and B1 and B2. Drilled piles are foundation of a polyfunctional building. Drilled piles are support of reinforced concrete grillage, which are from strips foundation and foundation pads. Cast-in-place concrete frame is a form of load-bearing structure, which contens plate ceilings, pillars and walls. Peripheral masonry is from hellow clay blocks, which are between cast-in-place concrete frame. Diploma thesis includes technical report, plan of building side, schedule and the budget of the building, technological instructions, radon prevent, control and testing plan, safety, balance resources, selected constructional details, machinery composition, bill of quantities.