The paper thematizes the concept of science in mid- and late thinking of Friedrich Nietzsche in the context of his understanding of scientific cognition of both: human and its world. The study introduces the problem of science and cognition in general in connection with significant motives of Nietzsche's thinking: morality, the revaluation of all values, thinking and living "beyond good and evil", freedom, human body, the superhuman motive, ascetic ideals, and more. Emphasis is put on the problem of veracity in the context of Nietzsche's attitude to idealism. Keywords Human; Superhuman; Nietzsche; Moral Philosophy; Cognition; Truth; Error; Intelect; Body; The Will to Power; Drive and Instinct; Evolution; Idealism; Nihilism; Amor fati; Beyond Good and Evil; Freedom; Ascetic ideals