There has been rapid change in the landcover/landuse in the Mekong delta, Viet Nam. The landcover/landuse has changed very fast due to intense population pressure, agriculture/aquaculture farming and timber collection in the coastal areas of the delta. The changing landuse pattern in the coastal areas of the delta is threatened to be flooded by sea level rise; sea level is expected to rise 33 cm until 2050; 45 cm until 2070 and 1 m until 2100. The coastline along the eastern Mekong delta has never been static, but the loss of mangrove forests along the coast has intensified coastline change. The objective of the present study is to map the changes in landcover/landuse along the eastern coast of the Mekong delta; and to detect the changes in position of the eastern coastline over the time period from 1989 to 2002.To detect changes in landuse, two satellite images of the same season, acquired by the TM sensor of Landsat 5 and the ETM+ sensor of Landsat 7 were used. The TM image was acquired on January 16, 1989 and ETM+ image was acquired on February 13, 2002. The landcover/landuse classes selected for the study are water, forest, open vegetation, soil and shrimp farms. Image differencing and post classification comparison are used to detect the changes between two time periods. Image to image correction technique is used to align satellite images. Maximum likelihood supervised classification technique is used to classify images. The result of the classification consists of five classes for 1989 and 2002, respectively. Overall accuracies of 87.5% and 86.8%, with kappa values of 0.85 and 0.84 are obtained for landuse 1989 and landuse 2002, respectively. The overall accuracy for the change map is 82% with kappa value 0.80. Post classification comparison is carried out in this study based on the supervised classification results. According to the results obtained from the post classification comparison, a significant decrease of 48% in forest and a significant increase of 74% in open vegetation and 21% in shrimp farms area observed over the entire study area. The coastline obtained by the combination of histogram thresholding and band ratio showed an overall advancement towards the South China Sea. The results showed that new land patches emerged along the eastern coast. The amount of new land patches appeared along the coast of the Mekong delta is approximately 2% of the entire study area.