Introduction: The patient exposure of loud sounds and noise in the intensive care unit has a negative effect on patients and results in suffering and risk for complications such as sleeping disorders, anxiety, delirium and stress resulting in negative physiological response with cardiovascular impact. Aim: To compile effects of interventions to reduce patient exposure from noise in the intensive care unit. Method: A quantitative descriptive review with a systematic approach. Electronic databases used for article search was PubMed and CINAHL. Included articles was reviewed separately and assessed for quality. A thematic analysis of the result was conducted using method and result matrices. Evidence for the effects of the interventions was evaluated according to the GRADE system. Results: The study included 18 articles. Blocking noise using ear protection had a positive impact on sleep and listening to music and nature based sounds showed lower levels of anxiety (+++). Listening to music and nature sounds also lowered blood pressure, heart rate and the need for anesthetics (++). Studies on quiet time-protocol had contradictory results and the evidence was deemed to be insufficient (+) to draw any conclusions. Conclusion: There is evidence to support the beneficial effects of noise blocking ear protection to promote sleep and listening to music or nature sounds to lower levels of anxiety in the intensive care unit. The evidence for the effects of music and nature sounds in lowering use of anesthetics and help lowering blood pressure and heart rate is more limited. More high-quality studies are needed