This paper presents research on isolated human remains from Grasshopper Pueblo and analyzes the processes by which bone becomes displaced from burials. Isolated human bone has never been systematically examined, which represents a significant gap in the study of the prehistoric American Southwest. This research is important because it is the first determination of the pattern of isolated bone found at an archaeological site and the formation processes that are responsible. It is also relevant for the creation of a standard isolated bone methodology and because it enables a better understanding of burial assemblages and anomalous assemblages of culturally modified bone.Subadults dominate the assemblage and larger elements are better represented than smaller elements. Most of the modifications present are postmortem but perimortem breakage and toolmarks are also present. This research produced a baseline of detailed data on isolated human bone in which patterns and anomalies can be inferred; the results suggest multiple causes of the isolation of the specimens, including prehistoric cultural disturbance, rodent disturbance, and the process of excavation.