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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
31

Régulation de la réponse immunitaire par les protéines kinases C

Springael, Cécile January 2010 (has links)
Doctorat en Sciences médicales / info:eu-repo/semantics/nonPublished
32

Prostaglandin F ��-induced signal transduction mechanism regulating the secretion of oxytocin from the bovine corpus lutem

Orwig, Kyle Edwin 23 May 1994 (has links)
Graduation date: 1995
33

Chloride Channel 2 and Protein Kinase C Epsilon Protein Module in Ischemic Preconditioning of Rabbit Cardiomyocytes

Kuzmin, Elena 12 February 2010 (has links)
Cardiac ischemic preconditioning (IPC) is defined as brief periods of ischemia and reperfusion that protect the heart against longer ischemia and reperfusion. IPC triggers Cl- efflux and protein kinase C epsilon (PKCe) translocation to the particulate fraction. Chloride channel 2 (ClC-2) is volume regulated and is a potential end effector of IPC. The goal of my study was to investigate the involvement of PKCε and ClC-2 protein module in IPC of isolated adult rabbit ventricular myocytes. Co-immunoprecipitation (co-IP) assays on HEK 293 cells, transfected with ClC-2-Flag, confirmed that ClC-2 interacts with PKCe. Subcellular fractionation showed that PKCe/ClC-2 protein module is localized to the sarcolemma of cardiomyocytes. Lastly, ischemia/reperfusion injury was simulated in cardiomyocytes with 45min simulated ischemia (SI)/60min simulated reperfusion (SR) and IPC was induced by pre-treatment with 10min SI/20min SR. Co-IP after each time interval showed that IPC transiently enhanced PKCe/ClC-2 interaction. PKC inhibitor, GF109203X, abrogated the enhanced interaction.
34

Chloride Channel 2 and Protein Kinase C Epsilon Protein Module in Ischemic Preconditioning of Rabbit Cardiomyocytes

Kuzmin, Elena 12 February 2010 (has links)
Cardiac ischemic preconditioning (IPC) is defined as brief periods of ischemia and reperfusion that protect the heart against longer ischemia and reperfusion. IPC triggers Cl- efflux and protein kinase C epsilon (PKCe) translocation to the particulate fraction. Chloride channel 2 (ClC-2) is volume regulated and is a potential end effector of IPC. The goal of my study was to investigate the involvement of PKCε and ClC-2 protein module in IPC of isolated adult rabbit ventricular myocytes. Co-immunoprecipitation (co-IP) assays on HEK 293 cells, transfected with ClC-2-Flag, confirmed that ClC-2 interacts with PKCe. Subcellular fractionation showed that PKCe/ClC-2 protein module is localized to the sarcolemma of cardiomyocytes. Lastly, ischemia/reperfusion injury was simulated in cardiomyocytes with 45min simulated ischemia (SI)/60min simulated reperfusion (SR) and IPC was induced by pre-treatment with 10min SI/20min SR. Co-IP after each time interval showed that IPC transiently enhanced PKCe/ClC-2 interaction. PKC inhibitor, GF109203X, abrogated the enhanced interaction.
35

<>.

Vincent, Fanny Crozatier, Bertrand. January 2005 (has links) (PDF)
Thèse de doctorat : Biologie cellulaire et moléculaire : Paris 12 : 2005. / Titre provenant de l'écran-titre. Bibliogr.
36

Rôle de la protéine C-MIP dans la physiopathologie moléculaire du syndrome néphrotique à lésions glomérulaires minimes

Kamal, Maud Sahali, Djillali January 2007 (has links) (PDF)
Thèse de doctorat : Biologie cellulaire et moléculaire : Paris 12 : 2007. / Thèse uniquement consultable au sein de l'Université Paris 12 (Intranet). Titre provenant de l'écran-titre. Bibliogr. 268 réf.
37

Role of protein kinase C isoforms in human breast tumor cell survival

McCracken, Meredith A., January 2002 (has links)
Thesis (Ph. D.)--West Virginia University, 2002. / Title from document title page. Document formatted into pages; contains xii, 161 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 140-158).
38

Protein kinase C signaling in normal and abnormal palate development in mice

Balasubramanian, Ganesh, January 2000 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2000. / Typescript. Vita. Includes bibliographical references (leaves 90-104). Also available on the Internet.
39

Regulation of SNARE protein interaction with Cav2.2 channels by protein phosphorylation /

Yokoyama, Charles Takeshi, January 2002 (has links)
Thesis (Ph. D.)--University of Washington, 2002. / Vita. Includes bibliographical references (leaves 117-136).
40

Regulation of equilibrative nucleoside transporter-1 by protein kinaseC and mitogen-activating protein kinase

Cheng, Kwan-wai., 鄭軍偉. January 2005 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences

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