This paper deals with studying skeletal animation techniques, and the subsequent design and implementation of skeletal animation extension for the GPUEngine library. The theoretical part describes the techniques of animation, skeletal animation and skinning. The following is an analysis of existing skeletal animation systems. The proposed solution seeks to reduce the data redundancy in the memory while rendering more skeletal models. According to the design a basic skeletal animation system has been implemented. Furthermore, a demonstration application has been created showing the skeletal system's use. The resulting skeletal system can be used in simple 3D applications and can serve as a basis for further works.

This thesis is focused on research of the rondel (circular ditch) located in the Prague- -Ruzyně area, dated to Late Neolithic Era with the Stroked Pottery culture. Quantitative, qualitative and spatial analysis of rondel's object fillings were carried out and the results and interpretation are presented in this thesis. Particularly thanks to Stroke-ornamented pottery analysis, it was possible to determine the relative chronology of the ditches filling. The interpretation of the material analysis and material spatial distribution tried to describe the trends associated with the formative processes and the development of origin of the ditches fillings. This work brings the results of processing of archeological findings and field documentation of a fully explored rondel, situated in the settlement of the Stroked Pottery culture. This work contributes to the understanding of Late Neolithic settlement structure and the rondels in general. Catalogue of findings is included. KEY WORDS: Late Neolithic - Stroked Pottery culture - Circular ditch - spatial analysis - formation processes - pottery - lithics - daub - animal skeletal remains

Hyperglycemia in critically ill patients was considered for many years an adaptive response to stress conditions being present in both patients with and without previous history of diabetes. Hyperglycemia is caused mainly by peripheral insulin resistance induced by the factors acting counteracting insulin signalling at the postreceptor level. Furthermore, hyperglycemia itself can then increase serum levels of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α), interleukin-6 (Il-6) and interleukin-8 (Il- 8) and others. On the contrary, peripheral insulin resistance induced by pro- inflammatory cytokines may further potentiate hyperglycemia. White adipose tissue represents in addition to its energy storage function also a very active endocrine active organ. In addition to regulation of a number of metabolic processes it also significantly modulates the inflammatory response. In critically ill patients, adipose tissue changes its morphology, i.e. the adipocytes are shrinking and adipose tissue is abundantly infiltrated by macrophages. Paradoxically, overweight and obese critically ill patients have lower mortality than underweight, lean and morbidly obese subjects. In our studies, we selected population of the patients undergoing elective major cardiac surgery with extracorporeal...

The influence of biological relationships on the morphology of the human skeleton is a current theme in bioarchaeology and forensic research. Whether it is the discovery of kinship relationships in an anonymous cemetery or the question of individual identification based on familial similarity, research is limited by a number of factors. Above all, there is the shortage of osteological assemblages with genealogical documentation. Most such samples also include only a small number of individuals, and thus the number of different degrees of their relatedness is limited. Related to this is the lack or absence of methods suitable for either the exact expression of the degree of morphological similarity between individuals or the statistical evaluation of results. However, for this dissertation an opportunity arose to analyze several osteological assemblages with genealogical documentation from the 17th to 20th centuries, comprising almost one hundred individuals. This represents one of the largest such units in the world to date. The individual samples also include several cases of consanguineous marriages with subsequent generations. The aim of the first part of the dissertation is to propose new methodological approaches to expressing the degree of similarity of individuals based on different types of...

Design, exoskeleton, overhead work, fatigue, human body, musculoskeletal disorder