Diploma thesis "Comparison of natural humic substances fluorescence" is aimed at identification of soil humic substances and natural humic substances using fluorescence spectroscopy. Results showed that fluorescence of humic acids isolated from lignite was similar to soil humic acids and was registered at longer wavelength. On the other hands lignohumate had higher fluorescence intensity at shorter wavelength. Fluorescence spectroscopy is a useful tool for identification of humic substances isolated from different sources.

The work deals with (in a literary summary) résumé of the knowledge about european elder [Sambucus nigra L.], it also describes the content of important substances and its utilization. The samples were collected at selected areas. The obtained samples were analyzed at the Research Institute of Brewing and Malting, a.s. using a UPLC liquid chromatograph with a PDA detector. It was determined the content of chlorogenic acid, vanilic acid, coffee acid, coumaric acid, quercetin, rutin, isoquercitrin and hyperoside was determined. The highest content was found in the extraction of free phenolic substances.

This thesis, which is performed as an experiment, deals with dependence of locations on the amount of extractive substances in the heartwood, sapwood and bark of acacia (Robinia pseudoacacia L.) across radius of the trunk. Thesis also aims to determine at what part of the trunk is situated most of extractive substances. Furthermore is evaluated, if the amount of extractive substances is depending on the height of the trunk, at altitudes from 0 m and 1.3 m from which the samples were taken. A final point is to compar according to the cardinal directions. In the theoretical part is described the issue of extractive substances and chemical composition of acacia. The second part presents the measured values from taked and extracted samples and their statistical evaluation.

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Charles University in Prague Faculty of pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Katarína Valová Supervisor: PharmDr. Marie Vopršálová, CSc. Title of diploma thesis: Misuse of doping substances My diploma thesis describe the term doping, possible causes of doping and its prevalence. It contains the outline of doping substances and methods, the characteristics of individual groups, the mechanism of action as well as the adverse effects of the substances on the health of sportsmen. I also focused on anti-doping organs and testing methods or describing new possibilities in in the fight against doping. I briefly described the process of the doping control and as well as the sanctions.

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