Thesis (M.A.)--Boise State University, 2009. / Includes bibliographical references (leaves 73-77).

Four analogues of the Lewis X trisaccharide antigen (β-D-Galp(1→4)[α-L-Fucp(1→3)]-D-GlcNAcp) in which the galactosyl residue is modified at O-4 as a methyloxy, deoxychloro, deoxyfluoro or deoxy were synthesized. The preparation of the modified 4-OMe, 4-Cl, 4-F and 4-H trichloroacetimidate galactosyl donors is described as well as their use in the glycosylation of an N-acetylglucosamine glycosyl acceptor. The resulting disaccharides were deprotected at O-3 of the glucosamine residue and fucosylated giving access to the desired protected Lewis X analogues. One step global deprotection (Na/NH3) of the protected 4”-methoxy and 4”-deoxy analogues, and two step deprotections (removal of a p-methoxybenzyl with DDQ, then Zemplén deacylation) of the 4”-deoxychloro and 4”-deoxyfluoro protected Lex analogues gave the desired compounds in good yields. The relative binding energies of the 4” manipulated Lewis X methyl glycoside analogues for anti-Lewis X mAb SH1 were determined using competitive ELISA procedures. The binding experiments revealed that substitution of the 4” site with a deoxychloro, deoxyfluoro or deoxy function had a large differential change in the free energy of binding; yet they did not completely abolish cross reactivity with native Lewis X. Substitution with a methyloxy function eliminated recognition by anti-Lewis X monoclonal antibody SH1. / NSERC

This study examines the links between architecture and literature through the work of English author/mathematician/geometrician Lewis Carroll/Charles L. Dodgson. The premise is that throughout Carroll's work, questions concerning the position of the body in relation to its surroundings---the possibility for one to forge a sense of place---are recurrent. Carroll stages a series of bodily movements in space: changes in scale, transformations, alterations, translations from bottom to top, from left to right, from the inside to the outside, and so on. Reading the work, one is constantly reminded that one's perception of space, as well as one's understanding of where one stands, are phenomena that take place in language, through utterances, through words. Approaching Carroll's work with particular attention to the space of bodily movements and to plays on language, one can access a subterranean architectural discourse. This discourse is oblique, suggested rather than explicit, but nonetheless raises pertinent questions concerning the formation of architectural meaning: the relationship of sense to its limits---to nonsense---in architecture. / The following texts are studied: Carroll's two architectural pamphlets; the two Alice stories with their convoluted spaces; a long epic poem dealing with the space of discovery; a drama on geometry and a logical exposition on the paradoxes of movement. Throughout Carroll's multifaceted work, nonsense guides the construction of the texts. Working at the limits of language and literary genres, Carroll's parodies possess strong allegorical powers: sense travels obliquely and the work remains enigmatic. However, the reader somehow understands the work; the experience of the work produces a certain kind of knowledge. / In architecture, meaning is also tied to its outer limits---to the polysemy of nonsense. Through one's experience of space, a stable and orderly building becomes heterogeneous, loaded with qualities and symbols. A sense of place emerges and meaning momentarily appears along the sinuous paths that run between bodily movements, thoughts, dreams, desire and words.

This study compares Elmer Gantry and The God-Seeker. Part one shows the preparations of the two novels. Part two discusses the critical receptions of the two novels. The material is gathered from books and publications.The comparison also includes a study of the two novels themselves. Using critical comment as a basis, the paper compares the structure and use of setting, character, plot, style and techniques within the two novels.

This thesis describes the development and rationalization of processes involved in a new methodology developed in our group, minor enantiomer recycling. The first part of the thesis addresses mechanistic studies of one of the reactions involved in minor enantiomer recycling, dual Lewis acid-Lewis base catalyzed acetylcyanation of aldehydes. The methodology uses a combination of a chiral titanium-salen  complex with a tertiary amine as a catalytic  system  in  the enantioselective  synthesis  of  O-acylated  cyanohydrins from aldehydes and ketonitriles. Mechanistic investigations revealed that the rate-determining step in the reaction changes, depending on the nature of the aldehyde that was used. It was also concluded that cyanohydrin is coordinated to the Lewis acid in the acylation step. The second part of the thesis deals with minor enantiomer recycling, a highly selective one-pot recycling system. In a first step the product is formed as a minor and a major enantiomer by asymmetric catalysis. Recycling of the minor enantiomer, by selective kinetic resolution, regenerates the starting material. Continuous addition of a second reagent, also involved in a coupled exergonic process, leads to an increase of both yield and enantiomeric excess. Recycling procedures for the synthesis of O-acylated and O-formylated cyanohydrins have been developed with high yield and high enantiomeric excess of the products. The study includes development of the systems, comparison to other methodologies in asymmetric catalysis, and attempts to understand the processes involved. / <p>QC 20141202</p>

This thesis studies the intellectual development of the painter and writer Wyndham Lewis (1882-1957). His career is seen as an unique expression of the creative and critical intelligence within modern society. The liberal, secular, and individualistic aspects of Lewis's thought are stressed. / The thesis concentrates on four aspects of Lewis's life and work. First, Lewis's relationship with T. E. Hulme, usually described as one of direct influence, is shown to be adversarial and complicated by basic differences of their worldview. Second, the nature of Lewis's fascism is discussed using a new reading of Hitler (1931). Third, Lewis's view of the position and the role of the artist in society is explained by studying three of his models of culture and society, each drawn from a different period of his career. Finally, the relationship of Lewis and Marshall McLuhan is examined to determine the nature and extent of the ideas passed on.

Thesis (B.A.)--Haverford College Dept. of Classics, 1998. / Includes bibliographical references.

Regensburg, Univ., Diss., 2007

Thesis (Th. M.)--Dallas Theological Seminary, 2004. / Includes bibliographical references (leaves 69-71).

Thesis (Th. M.)--Dallas Theological Seminary, 2004. / Includes bibliographical references (leaves [69]-71).