211 |
Helicobacter pylori molecular mechanisms for variable adherence properties /Vallström, Anna, January 2009 (has links)
Diss. (sammanfattning) Umeå : Umeå universitet, 2009. / Härtill 4 uppsatser.
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212 |
Commonsense and nonsense, a cultural-philosophical adventure in Alice's wonderlandFang, Xuan, January 2009 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2010. / Includes bibliographical references (leaves 121-126). Also available in print.
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213 |
Iconoclastic tradition in American literature /Sougstad, Timothy J. January 2001 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2001. / Typescript. Vita. Includes bibliographical references (leaves 225-232). Also available on the Internet.
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Iconoclastic tradition in American literatureSougstad, Timothy J. January 2001 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2001. / Typescript. Vita. Includes bibliographical references (leaves 225-232). Also available on the Internet.
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215 |
Principles of chemical reactivity on the Diels-Alder reaction in ionic liquids and Lewis acid large-scale computationsAcevedo, Orlando. January 2003 (has links)
Thesis (Ph. D.)--Duquesne University, 2003. / Title from document title page. Abstract included in electronic submission form. Includes bibliographical references.
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216 |
Synthesis, structure and reactivity of group 13 Lewis acids and group 4 metallocene zwitterions /Hair, Gregory Scott, January 1999 (has links)
Thesis (Ph. D.)--University of Texas at Austin, 1999. / Vita. Includes bibliographical references. Available also in a digital version from Dissertation Abstracts.
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217 |
Orual, a therapeutic appreciation masks, mirrors, and metamorphosis /Heikkila, David Laurie, January 1998 (has links)
Thesis (M.C.S.)--Regent College, 1998. / Abstract and vita. Includes bibliographical references (leaves 167-176).
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A director's approach to a production of Alice in Wonderland for touringRiggs, Rita Fern, 1930- January 1954 (has links)
No description available.
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The Monk and folkloreGaede, Ruth Brant, 1914- January 1956 (has links)
No description available.
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Glycosylating Enkephalins: Design, Glycosylation Using Sugar Acetates in the Preparation of Glycosyl Amino Acids for Glycopeptide Syntheses, Binding at the Opioid Receptors and Analgesic EffectsKeyari, Charles Mambo January 2007 (has links)
Improved procedures for the glycosylation of serine and threonine utilizing Schiff base activation are reported. The procedures are less expensive and more efficient alternatives to previously published methods. The Schiff bases exhibited ring-chain tautomerism in CDCl₃ as shown by ¹H NMR. Acting as glycosyl acceptors, the Schiff bases reacted at RT with simple sugar peracetate donors with BF₃•OEt₂ promotion to provide the corresponding protected amino acid glycosides in good yields. With microwave irradiation, the reactions were complete in 2-5 minutes. Glycosylation with the dipeptide Schiff base shows the potential of this method in the preparation of peptide building blocks. To investigate this reaction further, direct glycosylation of sugar acetates with FMOC-Ser-OH/OBZl under BF₃•OEt₂ promotion in a microwave provided glycosides in high yield. In addition to the expected glycoside products acetylated side products resulting from acetate migration were isolated, suggesting that activation of the anomeric sugar acetates with a Lewis acid such BF₃•OEt₂ led to an oxocarbenium ion, which rearranged to a 1,2-dioxocarbenium ion because of the acetate participating group at C-2. Solvent participation was also illustrated with acetate migration being more pronounced when CH₃CN was used as a solvent and resulted in less product yield and higher amounts of the acetylated product. The acyl transfer products in these reactions where sugar acetates serve as glycosyl donors is reported for the first time, which also implies that ortho-ester like intermediates are important in the reaction mechanism. Keeping the message segment constant in the sequence H-Tyr-DThr-Gly-Phe-Leu- Ser-CO-NH₂ and modification of the address segment with different carbohydrate moieties had little effect on selectivity for binding at the μ, δ, or κ-opiod receptors. However, substitution of D-threonine with D-serine or the less polar D-alanine in the message segment resulted in a loss of κ-receptor affinity. Further replacement of D-threonine with the more hydrophobic D-valine resulted in complete loss of κ-binding affinity generating pure μ-δ agonists. These data suggests that changes in the message segment of the pharmacophore results in the glycopeptide adopting a conformation that is less favorable for -binding receptor activity. Finally, the peripheral administration and i.c.v. tests of the drugs suggest that modifications in the message segment of the pharmacophore influences the potency of these compounds.
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