This master thesis deals with inhalation of fine particles and fibres into human lungs. This is a scientific field where computer modelling is used to describe the movement of fibres and their deposition in the lungs. However, the results of these simulations must be verified experimentally. The prediction of fibres behaviour is important from a toxicology point of view where it is important to know deposition hot-spots and places where fibres could possibly cause problems. The review of the state-of-the-art is focused on the deposition of particles in human lungs followed with a chapter on fibre as a type of particle, and occupational exposure limits set by different world associations. The last theoretical chapter describes human lungs and its diseases which can evolve when limits for occupational exposure are not met. The experimental chapter consists of a description of the used experimental setup and results from an experiment together with a comparison of results with other similar experiments.

This diploma thesis deals with analysis of the current state of recruiting – graduates, and comparing their requirements to the actual state of the company Motorola. Using questionnaire survey identifies criteria that prefer graduates in finding work, and on the basis of submitted proposals for streamlining the methods that used in recruiting.

The thesis is focused on the improvement of the work motivation in the company Plastika a.s. It has been made survey an analysis of the curent motivational system in the company using internal resources and questionnaire survey. Possibilities how to improve the motivation system of this company have been formed on the basis of result this analysis and identification shortcomings.

This diploma thesis deals with evaluation and optimization of the system of benefits in an engineering company. Introductory part of the thesis describes the basic ways to increase motivation of employees through the comprehensive system of remuneration and benefits. Next part of the thesis presents a comparison of benefits provided by companies operating in the Czech Republic and the particular engineering company ABC. Practical part of the thesis carries out a survey focused on the most frequently provided benefits by different companies. The thesis also includes the questionnaire in which the interest for specific benefits was expressed. The benefits in which the greatest interest was shown are supplied with a financial description of costs for the employer. The conclusion provides additional recommendations for further optimization of the questionnaire and specific proposals to improve the system of benefits in the engineering company ABC.

Thesis is focused on proposing changes of motivational system in pharmaceutical company. Specific changes of motivational system which improve effectiveness and satisfaction of pharmaceutical representants are based on realized research of actual motivational system in company and it´s theoretical basis.

Diploma thesis is dealing with the possibility of use of discrete event simulations in a production planning. The connection of the work measurement and the production planning is described. The thesis describes the modeling methodology, design and realization of the experiment with the model. The production planning part describes the processing of the data generated from the model, which are further used to demonstrate the planning method and optimization of the production plan.

Tonsillar cancer (TC) presents an important part of head and neck cancers and its incidence is rising in the Czech Republic. Cigarette smoking and alcohol abuse are risk factors responsible for approximately two thirds of all head and neck cancers. Furthermore, a role of human papillomavirus (HPV) as an independent risk factor has been demonstrated recently. The aims of the present study were to find demographical differences between the group of HPV-positive and negative patients, to determine the prevalence of HPV in TC of Czech patients and also to find out whether the virus in HPV DNA positive tumors is transcriptionally active. Another aim was to test different markers of HPV infection for a precise selection of patients with HPV associated disease and to determine the prognostic role of these markers. A set of 109 patients with primary TC was examined for HPV DNA presence in tumor tissue and for the presence of HPV specific antibodies in serum. Data regarding risk factors were obtained by questionnaires. Forty-five samples were available for E6 and E2 mRNA analysis and for immunohistochemical analysis of p16 and p53 expression. The overall prevalence of HPV DNA in TC was 65%. In 93% of HPV16 DNA positive samples the virus was transcriptionally active. The E2 expression status has shown that in...

1 Abstract Every year, the number of species considered as endangered increases, especially due to human activities. Nowadays, captive breeding in zoological gardens becomes an option for their survival in refugees. Zoological gardens function as so-called "Noah's Ark", which has the potential to shelter a large amount of individuals from many species. In the future, this opportunity may give us a chance to reintroduce a species that disappeared in the nature. There are many factors influencing which species will be selected to be kept in zoos, e.g., the IUCN status, taxonomical uniqueness, availability, etc., but it was found that especially the size of the animal and the human aesthetic preferences affect the selection. However, every group of animals is evaluated independently in the terms of beauty, and thus, it is necessary to detect these rules and then to apply them to conservation projects. This thesis examines the factors that influence human aesthetic preferences to mammals, both in terms of the characteristics of animals (their colour and morphology), and in terms of human factors (gender, age, education, residence). It was found that especially the pattern, saturation and overall lightness of the animal affect the evaluation of beauty in mammals. On the other hand, dark colours are evaluated...

The thesis is focused on an analysis of the recruitment process at the present time and the possibilities of usage of the machine learning in it. On this analysis is based a solution how to make the search process for suitable candidates in recruitment more effective by machine learning, specifically with the K-Means algorithm and the SOM neural network.

OF DIPLOMA THESIS Analysis of talent management in the company Karma s.r.o. The diploma thesis deals with the topic "Analysis of talent management in a selected organization", while the research took place in the company Karma, s.r.o. The aim of the work is to identify talent management in this company with the determination of recommended steps to improve the current situation, respectively. elimination of deficiencies. Due to the fact that this company providing communication and information services focuses on IT specialists, the connection of talent management in this company is crucial, among other things, in connection with the current state of the labor market and the current shortage of IT specialists. The research questions of this thesis are the following: How does talent management work in Karma? What recommendations can be given to Karma to improve the functioning of talent management? The research took place both in the form of a questionnaire survey and in the form of interviews. Ten respondents from the Human Resources Management Department took part in the questionnaire survey, and eleven respondents across the company were interviewed. The research was conducted through interviews mainly by middle management and project managers focusing on IT projects with longer experience...