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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Evolution of Genes and Gene Networks in Filamentous Fungi

Greenwald, Charles Joaquin 2010 August 1900 (has links)
The Pezizomycotina, commonly known as the filamentous fungi, are a diverse group of organisms that have a major impact on human life. The filamentous fungi diverged from a common ancestor approximately 200 – 700 million years ago. Because of the diversity and the wealth of biological and genomic tools for the filamentous fungi it is possible to track the evolutionary history of genes and gene networks in these organisms. In this dissertation I focus on the evolution of two genes (lolC and lolD) in the LOL secondary metabolite gene cluster in Epichloë and Neotyphodium genera, the evolution of the MAP kinase-signaling cascade in the filamentous fungi, the regulation of the gene networks involved in asexual development in Neurospora crassa, and the identification of two genes in the N. crassa asexual development gene network, acon-2 and acon-3. I find that lolC and lolD originated as an ancient duplication in the ancestor of the filamentous fungi, which were later recruited in the LOL gene cluster in the fungal endophyte lineage. In the MAP kinase-signaling cascade, I find that the MAPK component is the most central gene in the gene network. I also find that the MAPK signaling cascade originated as three copies in the ancestor to eukaryotes, an arrangement that is maintained in filamentous fungi. My observations of gene expression profiling during N. crassa asexual development show tissue specific expression of genes. Both the vegetative mycelium and the aerial hyphae contribute to the formation of macroconidiophores. Also, with the help of genomic tools recently developed by researchers in the filamentous fungal community, I identified NCU00478 and NCU07617 as the genes with mutations responsible for two aconidial strains of N. crassa, acon-2 and acon-3 respectively.
2

Modeling the impact of variable renewable energy sources penetration on supply-demand balance : Analysis of France from 2021 to 2025

DE LEON, RAFAEL January 2021 (has links)
France is planning a strong development of solar photovoltaics (PV) and wind power in the medium term disrupting the power system. This Master Thesis analyzes the impacts of variable renewable energy production on the supply-demand balance from 2021 to 2025 in France. The model used relies on a dynamic programming method. The analysis is based on the assessment of indicators such as price signals, margins, loss of load duration (LOLD), expected energy not served (EENS) and nuclear drop stop that characterize the supply-demand balance and the security of supply of the electricity system. Wind power and PV are two very different technologies. Their load factor is very sizeable as it characterize their seasonality, variability and predictability and has an impact on all medium-term indicators. Wind power and PV have low marginal costs and their production is seasonal and in anti-phase. With new installed capacity, their added production in the supply-demand balance will substitute first the imports from the interconnections until saturation and then nuclear and thermal power plant production. Prices decrease with the same seasonality as the production and need to be considered when establishing the nuclear planning for the years to come. In addition a re-optimization of hydro power is observed. In terms of security of supply, wind power is more efficient than PV when assessing the reduction of LOLD but both are far from the performance of combined cycle gas turbines (CCGT). Lastly, the lack of nuclear production opportunities increases considerably more with PV due to a very localised production during the day which coincides in summer with periods of low consumption. Wind power and PV are two distinct technologies and should not be put in the same category when assessing their impact on the power system. / Frankrike planerar en stark utveckling av solceller (PV) och vindkraft på medellång sikt för att störa kraftsystemet. Detta examensarbete analyserar effekterna av varierande produktion av förnybar energi på balans mellan utbud och efterfrågan från 2021 till 2025 i Frankrike. Modellen som används bygger på en dynamisk programmeringsmetod. Analysen baseras på bedömningen av indikatorer som prissignaler, marginaler, förlust av lasttid (LOLD), förväntad energi som inte serveras (EENS) och kärnkraftsfallstopp som kännetecknar efterfrågan och utbudssäkerheten för el systemet. Vindkraft och solceller är två mycket olika tekniker. Deras belastningsfaktor är mycket stor eftersom den kännetecknar deras säsongsvariation, variation och förutsägbarhet och påverkar alla medellångsiktiga indikatorer. Vindkraft och solceller har låga marginalkostnader och deras produktion är säsongsbetonad och i fas. Med ny installerad kapacitet kommer deras extra produktion i utbuds- och efterfrågan att ersätta importen från sammankopplingarna till mättnad och sedan produktion av kärnkraft och värmekraftverk. Priserna sjunker med samma säsong som produktionen och måste beaktas när kärnkraftsplaneringen fastställs för de kommande åren. Dessutom observeras en återoptimering av vattenkraften. När det gäller försörjningstrygghet är vindkraft effektivare än solceller vid bedömning av minskningen av LOLD men båda är långt ifrån prestanda för kombinerade cykelturbiner (CCGT). Slutligen ökar avsaknaden av kärnkraftsproduktionsmöjligheter betydligt mer med solceller på grund av en mycket lokal produktion under dagen som sammanfaller på sommaren med perioder med låg konsumtion. Vindkraft och solceller är två olika tekniker och bör inte placeras i samma kategori när man bedömer deras inverkan på kraftsystemet.

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