This thesis constitutes a first large-scale study of literary self-translators and self-translations in Canada, with self-translation understood as interlinguistic and intertextual transfer where the same legal person is responsible for writing the antecedent and subsequent texts. Three main questions guide this investigation: To what extent is Canada fertile ground for self-translation? What does it mean to self-translate in Canada? Why does self-translation in Canada matter? After situating Canada-based research within broader self-translation scholarship, I engage in a critical analysis of the definition and implications of self-translation and contextualize the theoretical, sociopolitical and methodological rationale for studying Canada and adopting a macroscopic approach to examining self-translations and their writers in this country. The thesis predominantly revolves around self-translation artefacts produced by three groups of writers who self-translated in Canada at least once between 1971 and 2016: 1) those self-translating exclusively between English and French; and those self-translating into and/or out of 2) Spanish; or 3) standard Italian. Exploring the theme of collaboration, I propose a new typology of collaborative self-translation, attempting to account for both process- and product-related considerations. In examining the theme of frequency, I identify self-translators and discuss their relative distribution vis-à-vis language, generation, country of birth and location within Canada; I also map out a conceptual framework for defining and counting self-translation products, proposing new ways of understanding and classifying writers in light of their self-translational productivity. In considering the theme of language, I analyze how writers and their self-translations can be characterized in relation to language variety, language combinations and language directionality. In this thesis, I argue that Canada is a significant hub of heterogeneous self-translational activity, and that large-scale, quantitative and product-oriented study constitutes a useful research approach that can generate rich findings and complement other forms of investigation. The thesis also contains an extensive appendix in which I identify Canadian self-translators and their self-translations.