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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Investigations of Influenza Vaccination in Kidney and Lung Transplant Populations

Bergeron, Amber Unknown Date
No description available.
2

Investigations of Influenza Vaccination in Kidney and Lung Transplant Populations

Bergeron, Amber 06 1900 (has links)
These two studies investigate the immune responses of lung and kidney transplant recipients to the influenza vaccine. The study involving kidney transplant recipients developed a novel flow cytometry assay to measure cell-mediated immunity in response to influenza vaccination. The activation of T-cells was assessed through the change in T-cell production of interferon gamma after vaccination. In lung transplant recipients, the study examined the formation of de novo anti-HLA antibodies following influenza vaccination. Anti-HLA antibodies were classified as donor-specific or not. The study in kidney transplant recipients found that the influenza vaccine is effective at stimulating the immune response and producing long-lived memory in these patients, as evidenced by high baseline T-cell activity. The study of lung transplant recipients found that receiving the influenza vaccine did not result in the production of anti-HLA antibodies. Both studies found vaccine to be safe for use in these populations. / Experimental Medicine

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