The prevalence of medication errors in a major teaching hospital was investigated using several methodologies. The existing ward stock drug distribution system was assessed and a new system designed based on a novel use of failure mode and effects analysis. The existing system was compared to the new unit supply individual patient dispensing system on two wards in terms of medication errors, nursing time, pharmacy time, drug costs, drug security and nurses' opinion. A review of a one year sample of reports submitted under the existing incident reporting scheme was also undertaken. Errors were categorised according to drug group, error type, reason cited for the error, and probability ranking (probability of occurrence, detection and harm). In addition, a "no-blame" medication error reporting scheme was implemented and assessed.Results of the study showed that in the newly designed individual patient dispensing system there was a reduction in nursing time associated with medication activities of approximately 29%, an increase in pharmacy staff time of 64%, a reduction in drug costs and an increase in drug security. Using the disguised observer methodology a reduction in medication errors by 23.5% (including timing errors) and 7.3% (excluding timing errors) was seen on Ward A. Similarly a reduction of 21.1% (including timing errors) and 9.8% (excluding timing errors) was observed on Ward B. Significant support for the individual patient dispensing system was given by nursing staff. Of the errors self-reported under the existing incident/accident reporting scheme the most common type of error was omissions (32.2%), the most common drug group was cardiovascular drugs (19.8%), and the most common cause of the error cited was a faulty check (42.3%). The probability ranking showed that 75% of errors reported scored between 12 and 17 points (from a possible 30 points). In ++ / the no-blame error reporting system, an error rate of 2.1% was detected in the existing system and 1.7% in the failure mode analysis designed phase.

The diploma thesis surveys the most important problematic fields of the patient safety issue; particularly in the context of drug administration. In the general part there are described the risks associated with LASA medications, using of concentrated electrolyte solutions, incorrect patient identification and wrong communication. Reported clinical cases of medication errors that occurred in connection with the triggers mentioned above are demonstrated and there are listed recommendations aimed at preventing the adverse events and assuring safe care. The closing part of the thesis describes and compares how the Antwerp University Hospital and three teaching hospitals in Prague ensure the safety of drug administration. The thesis manifests a noticeably more elaborate system of education and promotion of the patient safety issues both among the staff and among the patients and their families in the Antwerp University Hospital. Also the technical assuring of the right medication (barcode scanners, automated dispensing devices in certain wards etc.) was in the Belgian hospital on higher level comparing to the average of the followed Czech hospitals.

RATIONALE AND AIM: The double checking of medicines in health care is a contestable procedure. It occupies an obvious position in health care practice and is understood to be an effective defence against medication error but the process is variable and the outcomes have not been exposed to testing. This paper presents an appraisal of the process using data from part of a larger study on the contributory factors in medication errors and their reporting. METHODS: Previous research studies are reviewed; data are analysed from a review of 991 drug error reports and a subsequent series of 40 in-depth interviews with health professionals in an acute hospital in northern England. RESULTS: The incident reports showed that errors occurred despite double checking but that action taken did not appear to investigate the checking process. Most interview participants (34) talked extensively about double checking but believed the process to be inconsistent. Four key categories were apparent: deference to authority, reduction of responsibility, automatic processing and lack of time. Solutions to the problems were also offered, which are discussed with several recommendations. CONCLUSIONS: Double checking medicines should be a selective and systematic procedure informed by key principles and encompassing certain behaviours. Psychological research may be instructive in reducing checking errors but the aviation industry may also have a part to play in increasing error wisdom and reducing risk.

No description available.

Objective. Analyze quality improvement (QI) education across US pharmacy programs. Methods. This was a two stage cross-sectional study that inspected each accredited school website for published QI curriculum or related content, and e-mailed a questionnaire to each school asking about QI curriculum or content. T-test and chi square were used for analysis with an alpha a priori set at .05. Results. Sixty responses (47% response rate) revealed the least-covered QI topics: quality dashboards /sentinel systems (30%); six-sigma or other QI methodologies (45%); safety and quality measures (57%); Medicare Star measures and payment incentives (58%); and how to implement changes to improve quality (60%). More private institutions covered Adverse Drug Events than public institutions and required a dedicated QI class; however, required QI projects were more often reported by public institutions. Conclusion. Despite the need for pharmacists to understand QI, it is not covered well in school curricula.

Medication errors are one of the most common causes of patient injuries in healthcare systems. Poor labelling has been identified as a contributing factor of medication errors, particularly for those involving injectable drugs. Colour coding and colour differentiation are two major techniques being used on labels to aid drug identification. However, neither approach has been scientifically proven to minimize the occurrence of or harm from medication errors. This thesis investigates potential effects of different approaches for using colour on standardized labels on the task of identifying a specific drug from a storage area via a controlled experiment involving human users. Three different ways of using colour were compared: labels where only black, white and grey are used; labels where a unique colour scheme adopted from an existing manufacturer’s label is applied to each drug; colour coded labels based on the product’s strength level within the product line. The results show that people might be vulnerable to confusion from drugs that have look-alike labels and also have look-alike, sound-alike drug names. In particular, when each drug label had a fairly unique colour scheme, participants were more prone to misperceive the look-alike, sound-alike drug name as the correct drug name than when no colour was used or when colour was used on the labels with no apparent one-to-one association between the label colour and the drug identity. This result could suggest a perceptual bias to perceive stimuli as the expected stimuli especially when the task involved is familiar and the stimuli look similar to the expected stimuli. Moreover, the results suggest a potential problem that may arise from standardizing existing labels if careful consideration is not given to the effects of reduced visual variations among the labels of different products on how the colours of the labels are perceived and used for drug identification. The thesis concludes with recommendations for improving the existing standard for labelling of injectable drug containers and for avoiding medication errors due to labelling and packaging in general.

Medication errors are one of the most common causes of patient injuries in healthcare systems. Poor labelling has been identified as a contributing factor of medication errors, particularly for those involving injectable drugs. Colour coding and colour differentiation are two major techniques being used on labels to aid drug identification. However, neither approach has been scientifically proven to minimize the occurrence of or harm from medication errors. This thesis investigates potential effects of different approaches for using colour on standardized labels on the task of identifying a specific drug from a storage area via a controlled experiment involving human users. Three different ways of using colour were compared: labels where only black, white and grey are used; labels where a unique colour scheme adopted from an existing manufacturer’s label is applied to each drug; colour coded labels based on the product’s strength level within the product line. The results show that people might be vulnerable to confusion from drugs that have look-alike labels and also have look-alike, sound-alike drug names. In particular, when each drug label had a fairly unique colour scheme, participants were more prone to misperceive the look-alike, sound-alike drug name as the correct drug name than when no colour was used or when colour was used on the labels with no apparent one-to-one association between the label colour and the drug identity. This result could suggest a perceptual bias to perceive stimuli as the expected stimuli especially when the task involved is familiar and the stimuli look similar to the expected stimuli. Moreover, the results suggest a potential problem that may arise from standardizing existing labels if careful consideration is not given to the effects of reduced visual variations among the labels of different products on how the colours of the labels are perceived and used for drug identification. The thesis concludes with recommendations for improving the existing standard for labelling of injectable drug containers and for avoiding medication errors due to labelling and packaging in general.

No / Observational methods as part of a qualitative approach have been specifically employed in the study of drug error and have undeniable strengths. This position paper will examine some recent research raising a number of ethical, and tangentially, methodological issues concerning the qualitative study of drug errors within United Kingdom National Health Service hospitals. Reflections on the views and ethical conduct of other qualitative researchers are provided to contextualize the discussion. Background.¿ The impact of a drug error, and any resultant adverse event can be significant. The human and financial costs are considerable. Establishing an accurate estimation of the frequency of adverse event and reporting rates has been difficult; additionally, methodological weaknesses in medical error research have sometimes caused further difficulties. Unsurprisingly, observational studies and for that matter, a whole range of other methods are now being considered in the quest to establish both understanding and predictability in relation to medical error. Relevance to clinical practice.¿ It is argued here that any participants in medical error research should be treated in a way that takes account of the prevailing culture of health care and, in the United Kingdom, the current ethos of government policy on medical error. This requires gaining informed consent, promoting transparency in method, and providing the opportunity for participants to learn. Effective error researchers can clearly increase the available knowledge in this critical area but ethical considerations and their chosen methods should show an appropriate level of respect for their participants. Carefully implemented qualitative approaches can help realize such respect.

The impact of Computerized Physician Order Entry (CPOE) on the dependent variables of medication-order compliance and time to first dose of antibiotic was investigated in this quasi-experimental study of a naturally-occurring CPOE intervention. The impact of CPOE on compliance and time to first dose was assessed by comparing measures of these variables from the intervention site and a non-equivalent control before and during intervention phases. Medication orders placed using CPOE were significantly more compliant than paper-based medication orders (p<.001), and first doses of antibiotic ordered using CPOE were delivered significantly faster than antibiotic orders placed using the paper-based system (p<.001). Findings support previous research indicating the positive impact of CPOE on patient safety as well as justify and enable future interventions to increase CPOE adoption and use among physicians. Additionally, data collected in this study will be used to provide behavior-based feedback to physicians as part of CPOE adoption and use intervention strategies to be explored in the forthcoming research. / Master of Science

Despite increased awareness about patient safety and quality of care, errors and adverse outcomes occur frequently in clinical practice. An estimated 10% of the 35.1 million U.S. hospital patients suffered injuries caused by medical errors; the most common were medication errors, which accounted for more than 50% of all medical errors. Work-related stress is associated with medication errors for health care professionals (HCP) in Saudi Arabia (SA) hospitals; however, the specific types of stressors and their effect on the level of medication errors have not been studied in SA. The purpose of this quantitative correlational study was to examine the relationship between the overall level and sources of work-related stress using the job stress scale on the level of medication errors for a group of 269 HCPs working at King Abdul-Aziz Hospital (KAH) in SA. The theoretical framework for this research was the Donabedian patient safety model, which relates healthcare quality to personal, environmental, and organizational factors. Binary logistic regression analyses indicated there was no relationship between overall levels of stress and medication errors. However, specific sources of work related stress such as disruption to home life, excessive workload, and night/weekend call duties were associated with a significant increase in the medication error rate, while pressure to meet deadlines and difficulties with colleagues was associated with a significant decrease in the medication error rate. Positive social change implications include how understanding the impact of work-related stress on medication errors by SA HCPs may lead to specific interventions to reduce medication errors and improve patient care.