Möjligheternas värld är en utställning som ska presenteras på olika mässor. Hjärtat i utställningen är automationsfabriken som är en automatiserad anläggning som ska tillverka leksaksbilar. Automationsfabriken ska invigas på mässan Scanautomatic och ProcessTeknikden 9-11 oktober 2012. Då möjligheternas värld är ett samarbete mellan näringsliv och skola bidrar företag och skolor med hjälp och samarbetar för att projektet ska bli lyckat. Prevas del i projektet är att ta fram ett styrsystem i form av ett MES och SCADA system till fabriken samtatt göra hemsidan där bilar kan beställas och integrera den med styrsystemet. Målet med examensarbetet är att utveckla styrsystemet och ta fram ett HMI genom att använda programvaror från Wonderware. Slutprodukten är i form av kod och objekt, och den funktionalitet de skapar tillsammans. Styrsystemet ska kunna kopplas upp mot fabriken och styra produktionen, förutsatt att övriga delar i projektet levererar det de ska. Arbetet började med att studera fabriken och etablera ett gränssnitt mellan styrsystemet ochPLCn som styr produktionsutrustningen, samt att ta fram ett grundläggande HMI. Sedan har ett simuleringsläge tagits fram med utgångspunk från gränssnittet för att simulera produktionsmiljön. Utifrån den här simuleringsmiljön och ett HMI har sedan funktioner tagits fram en i taget och testats, för att tillsammans senare utgöra den helhet som är styrsystemet. Här finns funktioner som beslutsprocesser för skapandet av nya produktions- och leveransordrar, hämtning av kundordrar, styrning av pick´n place enheten, informationshantering av innehållet i bufferten, samt registrering av alla ordrar och operationer i ett manufacturing execution system (MES). Styrsystemet har slutsligen kopplats samman med databasen där nya kundordrar registreras och genom att använda simuleringsmiljön och det HMI som utvecklats för fabriken har styrsystemet testats med goda resultat där styrsystemet klarar av att hantera hela produktionen från orderingång till leverans. / Möjligheternas värld is an exhibition that will be presented at various fairs. The heart of the exhibition is Automationsfabriken which is an automated facility that will manufacture toy cars. Automationsfabriken will be introduced at the fair Scanautomatic & ProcessTeknik, which takes place 9-11 October 2012. As Möjligheternas värld is a collaboration between industry and school, both businesses and schools are included in the project and work towards the success of the project. Prevas part of the project is to develop a control system in the form of a MES and SCADA system for the factory, to create the website where cars can be ordered, and to integrate the website with the control system. The goal of my thesis job is to develop the control system and to create an HMI using software from Wonderware. The final product is in the form of code and objects, and the functionality they create together. The control system should be able to connect to the factory and manage the production, provided that the other parts of the project are delivered according to the plan. The work began with a study of the factory, and to establish an interface between the control system and the PLC that controls the production equipment, as well as developing a basic HMI. After this was done a simulation environment was developed from the established interface in order to simulate the production environment. Based on this simulation environment and the HMI, functions has been developed one by one and tested in order to later become the whole which is the control system. It features functions such as decision-making for the creation of new production- and delivery orders, retrieval of customer orders, control of the pick´n placeunit, information handling of the content of the buffer, as well as registration of all orders and operations in the manufacturing execution system (MES). Finally the control system was connected to the database containing new customer order, and by using the simulation environment and the developed HMI for the factory the control system could be tested in order to confirm that the control system could handle the entire production from the intake of customer orders to delivery.

As plantas do gênero Cordyline possuem estruturas caulinares peculiares geralmente chamadas de rizoma. Um autor do início do século XX sugeriu que havia uma relação entre esse órgão de Cordyline e o órgão formador de raiz de Selaginella. O termo rizóforo foi originalmente cunhado para Selaginella e significa \"órgão portador de raízes\" e também passou a ser aplicado aos órgãos caulinares subterrâneos de Vernonia, Dioscorea e Smilax e ao que tradicionalmente era chamado de raiz aérea em Rhizophora mangle. Recentemente admitiu-se que as estruturas de Cordyline fruticosa são rízóforos, mas nenhum estudo de desenvolvimento foi apresentado a fim de confirmar tal hipótese. Rizóforo é um caule com geotropismo positivo não originário da plúmula do embrião, presente em plantas com sistema caulinar bipolar de ramificação, isto é, a planta possui ramos aéreos, as quais tem geotropismo negativo e formam folhas, e ramos basais, os quais tem geotropismo positivo e formam raízes. Em Cordyline, os rizóforos se desenvolvem a partir de gemas laterais e possuem crescimento secundário do mesmo modo que o eixo aéreo. O espessamento do caule de Cordyline já foi amplamente analisado em sua porção aérea, mas trabalhos a respeito da porção caulinar subterrânea são mais escassos. Esse espessamento é resultado direto e indireto da atuação do periciclo. No corpo primário, o periciclo produz tecido vascular adicional aumentando o diâmetro do caule concomitante com a atividade meristemática da endoderme. O periciclo ainda é o responsável pela formação do MES, o qual proporciona o espessamento secundário e atua de maneira semelhante na porção aérea e no rizóforo, com pequena variação. A vascularização das raízes adventícias conecta-se à vascularização do caule pelo periciclo durante o crescimento primário e pelo MES durante o crescimento secundário. As características morfológicas e anatômicas do rizóforo estão diretamente relacionadas com uma maior produção de raízes, assim, sua principal função é o aumento da rizosfera. Outras funções importantes dessa estrutura é o acúmulo de reservas e a reprodução vegetativa. O presente estudo averiguou a natureza dos órgãos subterrâneos de Cordyline fruticosa, C. australis e C, spectabilis, através de estudos anatômicos e observações do desenvolvimento ontogenético. / Plants of the genus Cordyline possess distinctive caulinar structures usually known as rhizomes. An author from the early twentieth century suggested that there was a relationship between this organ in Cordyline and the root-generating organ in Selaginella. The term rhizophore - meaning \"root-bearing organ\" - was coined originally for Selaginella and was later applied to the subterranean stem organs of Vernonia, Dioscorea and Smilax and to the structures traditionally known as aerial roots in Rhizophora mangle. Recently, these structures in Cordyline fruticosa have been categorized as rhizophores, but this hypothesis has not previously been confirmed by any published developmental study. A rhizophore is a stem with positive geotropism which does not arise from the plumule of the embryo, and is present in plants with a stem system having bipolar branching, i.e. with aerial branches, which have negative geotropism and form leaves, and basal branches, which have positive geotropism and form roots. The rhizophores of Cordyline develop from lateral buds and have secondary growth of the same type as in the aerial axis. The stem thickening of Cordyline has already been extensively studied in its aerial parts, but there are few such studies regarding the subterranean part of the stem. This thickening is the direct and indirect result of the activity of the pericycle. In the primary body, the pericycle produces additional vascular tissue, which increases the diameter of the stem concomitant with the meristematic activity of the endodermis. The pericycle is also responsible for the generation of the STM, which provides the secondary thickening and functions in a similar way in the aerial stem and the rhizophore, with little variation. The adventitious roots vascular tissue are connected to the vascular system of the stem by the pericycle during primary growth and by the STM during secondary growth. The morphological and anatomical features of the rhizophore are directly related to an increased production of roots, and thus its main function is the rhizosphere expansion. Beside that, the rhizophore is important as a storage organ and vegetative reproduction. The present study investigated the structure of the subterranean organs of Cordyline fruticosa, C. australis and C. spectabilis by anatomical techniques and observations of their ontogenetic development.

As plantas do gênero Cordyline possuem estruturas caulinares peculiares geralmente chamadas de rizoma. Um autor do início do século XX sugeriu que havia uma relação entre esse órgão de Cordyline e o órgão formador de raiz de Selaginella. O termo rizóforo foi originalmente cunhado para Selaginella e significa \"órgão portador de raízes\" e também passou a ser aplicado aos órgãos caulinares subterrâneos de Vernonia, Dioscorea e Smilax e ao que tradicionalmente era chamado de raiz aérea em Rhizophora mangle. Recentemente admitiu-se que as estruturas de Cordyline fruticosa são rízóforos, mas nenhum estudo de desenvolvimento foi apresentado a fim de confirmar tal hipótese. Rizóforo é um caule com geotropismo positivo não originário da plúmula do embrião, presente em plantas com sistema caulinar bipolar de ramificação, isto é, a planta possui ramos aéreos, as quais tem geotropismo negativo e formam folhas, e ramos basais, os quais tem geotropismo positivo e formam raízes. Em Cordyline, os rizóforos se desenvolvem a partir de gemas laterais e possuem crescimento secundário do mesmo modo que o eixo aéreo. O espessamento do caule de Cordyline já foi amplamente analisado em sua porção aérea, mas trabalhos a respeito da porção caulinar subterrânea são mais escassos. Esse espessamento é resultado direto e indireto da atuação do periciclo. No corpo primário, o periciclo produz tecido vascular adicional aumentando o diâmetro do caule concomitante com a atividade meristemática da endoderme. O periciclo ainda é o responsável pela formação do MES, o qual proporciona o espessamento secundário e atua de maneira semelhante na porção aérea e no rizóforo, com pequena variação. A vascularização das raízes adventícias conecta-se à vascularização do caule pelo periciclo durante o crescimento primário e pelo MES durante o crescimento secundário. As características morfológicas e anatômicas do rizóforo estão diretamente relacionadas com uma maior produção de raízes, assim, sua principal função é o aumento da rizosfera. Outras funções importantes dessa estrutura é o acúmulo de reservas e a reprodução vegetativa. O presente estudo averiguou a natureza dos órgãos subterrâneos de Cordyline fruticosa, C. australis e C, spectabilis, através de estudos anatômicos e observações do desenvolvimento ontogenético. / Plants of the genus Cordyline possess distinctive caulinar structures usually known as rhizomes. An author from the early twentieth century suggested that there was a relationship between this organ in Cordyline and the root-generating organ in Selaginella. The term rhizophore - meaning \"root-bearing organ\" - was coined originally for Selaginella and was later applied to the subterranean stem organs of Vernonia, Dioscorea and Smilax and to the structures traditionally known as aerial roots in Rhizophora mangle. Recently, these structures in Cordyline fruticosa have been categorized as rhizophores, but this hypothesis has not previously been confirmed by any published developmental study. A rhizophore is a stem with positive geotropism which does not arise from the plumule of the embryo, and is present in plants with a stem system having bipolar branching, i.e. with aerial branches, which have negative geotropism and form leaves, and basal branches, which have positive geotropism and form roots. The rhizophores of Cordyline develop from lateral buds and have secondary growth of the same type as in the aerial axis. The stem thickening of Cordyline has already been extensively studied in its aerial parts, but there are few such studies regarding the subterranean part of the stem. This thickening is the direct and indirect result of the activity of the pericycle. In the primary body, the pericycle produces additional vascular tissue, which increases the diameter of the stem concomitant with the meristematic activity of the endodermis. The pericycle is also responsible for the generation of the STM, which provides the secondary thickening and functions in a similar way in the aerial stem and the rhizophore, with little variation. The adventitious roots vascular tissue are connected to the vascular system of the stem by the pericycle during primary growth and by the STM during secondary growth. The morphological and anatomical features of the rhizophore are directly related to an increased production of roots, and thus its main function is the rhizosphere expansion. Beside that, the rhizophore is important as a storage organ and vegetative reproduction. The present study investigated the structure of the subterranean organs of Cordyline fruticosa, C. australis and C. spectabilis by anatomical techniques and observations of their ontogenetic development.

In recent years, government attention to Hi-Tech industry. Almost all the policies agree more on the Hi-Tech industry. This makes the management of the traditional industry the more difficult. Especially the textile industry. Face strong competition and consider the cost, enterprises move to other countries with lower cost of labor outside one after another. This causes the industry's cavity crisis of textile industry. Under the circumstances that the government policy profit is stimulated more. Enterprises implement e and automation. There are many failure examples of enterprise e. So, if can analyze the e course and research for the traditional industry, it maybe the traditional industry to consult the basis while assessing and implementation enterprise e, and then improve e probability succeeding. The rise of the internet network, has driven enterprise's electronic agitation, such famous diction as ERP, SCM, CRM, KM, BI, etc., All what's frequently heard can be repeated in detail in enterprises, should be according to accepting completely only? The demands of enterprises? The doing in the test amount of the cost? How to implement? It proofs CEO¡¦s management intelligence. The study probe the key factor of success for dyeing and finishing of traditional industry, by implement the information system.

Techn. University, Diss., 2005--Berlin.

The ERK-MAPK pathway is a dynamic signaling module, conserved across Eukarya, and capable of processing a myriad of environmental and cellular signals. It has been implicated in controlling important cell fate decisions in many cell types and species. In mES cells, growth factor activation of the ERK-MAPK pathway is involved in the earliest stages of lineage segregation, however very little is currently known about the mechanism by which this is accomplished. Taking a loss-of-function gene targeting approach I have reexamined the relative contribution of ERK2 activity to FGF-ERK signaling. Although ERK2 depletion results in an attenuation of the combined ERK1/2 activity, this is compensated for by the hyperactivation of the remaining ERK1 isozyme. Normal ERK1/2 function can be restored to ERK2 deficient cells by transgenic expression of either ERK1 or ERK2, indicating a degree of functional redundancy between both isoforms. When subjected to the appropriate cues, lineage commitment proceeded normally in ERK2 deficient cells, however increased self-renewal was observed under standard culture conditions. Several attempts were made to further probe ERK1/2 function by siRNA depletion, and dominant negative inhibition of ERK1 in Erk2 knockout cells, however both approaches failed to provide further insight. Furthermore, taking a candidate approach, the role of Srf, a canonical target of ERK1/2 signaling, was examined. Initial experiments indicated a role for SRK in neural differentiation, however due to issues of culture adaptation and instability in several cell lines it was not possible to conclude this line of research within the time frame of this thesis. IP-MS/MS analysis identified several proteins known to interact with ERK2 and indicated an involvement in nuclear pore function through TPR as well as transcriptional and translational regulation through RSK proteins. Moreover, this study identified DUSP6 and DUSP9 as the primary induced dual specificity phosphatases that regulate ERK2 activity in mES cells. To further probe the functional significance of the ERK:p90RSK interaction I examined a mES cell line genetically depleted for PDK1, a crucial regulator of p90RSK function. This cell line exhibits no detectable p90RSK activity, however in contrast to studies in other cell lines, p90RSK activity is dispensable for mitogen-induced cFos expression in mES cells. Subsequent experiments demonstrated a requirement for PDK1 activity in either the specification or maintenance of mES cell derived neurons. Further analysis indicated that p90RSK may be involved in a negative feedback loop regulating ERK1/2 activity, and if so may represent a point whereby ERK1/2 activity can be manipulated. To examine this I determined the effect pharmacological inhibition of p90RSK has on ERK1/2 activity and self-renewal using a novel p90Rsk inhibitor, BI-D1870. Although treatment with BI-D1870 correlated with enhanced ERK1/2 phosphorylation, the offtarget effects this molecule exhibits made it impossible to draw any firm conclusions from these experiments. Overall this study has demonstrated a degree of redundancy between ERK1/2 isozymes in mES cells. It has highlighted the complex nature of ERK1/2 regulation as well as the robustness of this pathway to perturbations in ERK dose. Furthermore, it has underscored some of the common pitfalls encountered when studying differentiation phenotypes in mES cells. Although this study failed to highlight anything more than a coincidental relationship between ERK1/2 activity and self-renewal capacity of mES cells, it has helped to highlight some important behavioral characteristics of the FGF-MAPK pathway in mES cells and provide a platform for further study.

With the arrival of the knowledge economy, the management of all enterprises attempt to increase the efficiency of organizing with information management, drive innovation, bring up a new wave of information management. Grow up and circulate the increase of the demand fast with information in the management activity of knowledge, the storing, searching, circulating and sharing of knowledge must be dependent on information science and technology to help, even on the knowledge innovation, information science and technology can also offer the function of deducing, summing up and making up etc., so a lot of enterprises will create knowledge management system while promoting the management engineering of knowledge, regarding KMS as the core of enterprise's knowledge management activity, in order to promote benefit carried on in enterprise's knowledge management activity. This research will regard staff of one international famous semiconductor company as case study, consider it with IS success model which announced by DeLone & McLean (2003) , and Wang Yu-Min (2003)" KMS success model " to try to set up and study the structure, take ' MES ' systematic field as an example, analyse its field demand situation, knowledge of administrative system, is it probe into with actual case relevant enterprise benefit and staff, knowledge of administrative system use to close of connecting with satisfaction to come, appraise from knowledge / information quality, system benefit, use, systematic quality and use satisfaction aspect systematically, and probe into the employee of enterprises to the analysis of using satisfaction of administrative system of knowledge. The research approach adopted in this research is an investigation method of the questionnaire, to verifying according to theory and research hypothesis by using the multiple-regression-analysis. We can get the result from the data that all these major factors incluing knowledge/ information quality, valuation of KMS benefits,system quality, system use has positive effects on the KMS satisfaction.

This diploma thesis "MES / MOM Systems in the Industry 4.0 concept" deals with the analysis, design and implementation of these systems. The first focus is on Industry 4.0 analysis, where are describe each part of Industry 4.0. Based on this knowledge, there were specified the changes in the MES / MOM systems. According to the changes and knowledge were designed and implemented the MES / MOM concept. The system communicates with the PLC using its own communicator and represents the data in the application environment. The application implements the Historian module and system modules. The PLC has an MS SQL protocol implemented so that the device can read and write data without the need to communicate with the parent system. This implementation is in line with Industry 4.0’s concept.

Esta dissertação propõe o estudo de um sistema de levantamento de dados e informações do chão de fábrica, baseando-se em conceitos de MES (Manufacturing Execution System) e em tecnologias de comunicação em rede de campo. Este sistema é capaz de garantir ações de monitoramento no chão de fábrica, como na comunicação de informações a diferentes áreas de uma corporação, integrando-se como um sub-sistema a um sistema de gestão integrado (Enterprise Resource Planning - ERP). Este sistema de levantamento de informações do chão de fábrica será integrado utilizando padrões de comunicação entre dispositivos e máquinas no ambiente industrial (I/O Bus) e módulos de software de monitoramento. Neste trabalho, o desafio adotado para ilustrar a tecnologia proposta envolve a integração de uma bancada que simula uma célula automática, constituída de atuadores e sensores controlados, por um controlador lógico programável (CLP), a sua integração a um software supervisório de processo e a geração de informações e sua disponibilidade para uma área de gerência corporativa. / This text considers the study of a data-collection and information system of shop-floor of a simulated industrial plant, based on concepts of MES (Manufacturing Execution System) and on technologies of communication in field bus. This system is capable to guarantee action of supervision of the industrial shop-floor, as in the communication of information the different areas of a corporation, combining itself as a subsystem to a major integrated system of management (ERP). This system of survey of shop-floor information will be integrated using standards of communication between devices and machines in the industrial environment (I/O Bus) and modules of supervision software (SCADA). In this work, the adopted challenge to illustrate the technology proposal involves the integration of an automatic cell, which consists the experiment environment, consisting of sensors and controlled actuators, for programmable logical controller (PLC), its integration to supervisory software of process and the generation of information and its availability for an area of corporative management.

Esta dissertação propõe o estudo de um sistema de levantamento de dados e informações do chão de fábrica, baseando-se em conceitos de MES (Manufacturing Execution System) e em tecnologias de comunicação em rede de campo. Este sistema é capaz de garantir ações de monitoramento no chão de fábrica, como na comunicação de informações a diferentes áreas de uma corporação, integrando-se como um sub-sistema a um sistema de gestão integrado (Enterprise Resource Planning - ERP). Este sistema de levantamento de informações do chão de fábrica será integrado utilizando padrões de comunicação entre dispositivos e máquinas no ambiente industrial (I/O Bus) e módulos de software de monitoramento. Neste trabalho, o desafio adotado para ilustrar a tecnologia proposta envolve a integração de uma bancada que simula uma célula automática, constituída de atuadores e sensores controlados, por um controlador lógico programável (CLP), a sua integração a um software supervisório de processo e a geração de informações e sua disponibilidade para uma área de gerência corporativa. / This text considers the study of a data-collection and information system of shop-floor of a simulated industrial plant, based on concepts of MES (Manufacturing Execution System) and on technologies of communication in field bus. This system is capable to guarantee action of supervision of the industrial shop-floor, as in the communication of information the different areas of a corporation, combining itself as a subsystem to a major integrated system of management (ERP). This system of survey of shop-floor information will be integrated using standards of communication between devices and machines in the industrial environment (I/O Bus) and modules of supervision software (SCADA). In this work, the adopted challenge to illustrate the technology proposal involves the integration of an automatic cell, which consists the experiment environment, consisting of sensors and controlled actuators, for programmable logical controller (PLC), its integration to supervisory software of process and the generation of information and its availability for an area of corporative management.