Made available in DSpace on 2016-04-04T18:28:01Z (GMT). No. of bitstreams: 1 Adriana Ap Ferreira 1.pdf: 2671092 bytes, checksum: 52bffd7181072105e7e3c13a4ab6f2c7 (MD5) Previous issue date: 2004-12-14 / With the increse of longevity and consequently the increase of scientific production about old age, it is necessary one analysis of the area's done knowledge. It was done a meta-analysis of the studies produced in the psychology area about old aged persons, in the PsycINFO database, on the first semester of 2003 (N=1281). It was analyzed: title, authors, type of work, themes, participants, reserch place, material used for data collection, and focus. In general, the titles presented a number of words within the recommended quantity, in 42,89% punctuation was not used and in 34,76% it was used colons. The authorship was predominantly multiple (90,1%), with majority male production. The reserch production is predominant (98,75%), and scientific journal is the most used vehicle for divulgation (98,4%). The most frequent themes were Social/Cultural Aspects, Psychological Aspects/ Chsrecte ristics and Diseases; there was a correlation botween the themes classified for the database anf the authors (r=0,98). The majorith of the studies compares old and adilt persons. America and Europe were the continents of major production. The majority of works were made in Health Services (37,71%) in which several types of instruments were used for data collection. The difference between the focus loss (21%) and gain (13,82%) was significant statistically. It is concluded that the area shows development signs. / Com o aumento da longevidade e conseq?ente aumento da produ??o cient?fica sobre velhice, faz-se necess?ria uma an?lise do conhecimento gerado na ?rea. Foi feita uma meta-an?lise dos estudos realizados na ?rea de psicologia sobre idosos, inseridos na base de dados PsyclNFO, no primeiro semestre de 2003 (N=1281). Foram analisados: t?tulo, autoria, tipo de trabalho, tem?tica, participantes, locais de realiza??o das pesquisas, materiais usados para a coleta de dados e enfoque. No geral, os t?tulos apresentaram n?mero de voc?bulos dentro do recomendado, sendo que em 42,89% n?o foi feito uso de pontua??o e em 34,76% foi utilizado dois pontos. A autoria foi predominantemente m?ltipla (90,1%), com maior produ??o mascul ina. A produ??o de pesquisas ? predominante (98,75%), sendo o peri?dico cient?fico o ve?culo mais utilizado para divulga??o (98,4%). Os temas mais freq?entes foram Aspectos Sociais! Culturais, Aspectos! Caracter?sticas Psicol?gicas e Doen?as; houve correla??o entre a classifica??o feita pela base e pelos autores (r=0,98). A maioria dos estudos compara idosos e pessoas adultas. Am?rica e Europa foram os cont?nentes de maior produ??o. A maioria dos trabalhos foi realizada em Servi?os de Sa?de (37,71 %), tendo sido usados v?rios tipos de instrumentos para a coleta dos dados. A diferen?a entre o enfoque perda (21 %) e ganho (13,82%) foi estatisticamente significante. Conclui-se que a ?rea mostra sinais de desenvolvimento.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-05-09T19:20:03Z No. of bitstreams: 1 LucasViegasFrancisco_DISSERT.pdf: 12755776 bytes, checksum: 6f4076fc7e5da064d04f53f1846a093a (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-05-09T22:36:52Z (GMT) No. of bitstreams: 1 LucasViegasFrancisco_DISSERT.pdf: 12755776 bytes, checksum: 6f4076fc7e5da064d04f53f1846a093a (MD5) / Made available in DSpace on 2016-05-09T22:36:53Z (GMT). No. of bitstreams: 1 LucasViegasFrancisco_DISSERT.pdf: 12755776 bytes, checksum: 6f4076fc7e5da064d04f53f1846a093a (MD5) Previous issue date: 2013-07-04 / At? o momento n?o h? um estudo que objetivou sintetizar a magnitude e varia??o do papel dos invertebrados aqu?ticos sobre a decomposi??o do detrito foliar em ambientes aqu?ticos. Al?m disso, existe uma falta de conhecimento sobre qual ? o impacto geral desses pequenos organismos na decomposi??o foliar. Al?m do mais, existe um quantidade de controv?rsias sobre como e quais devem ser os fatores mais influentes nesse processo ecol?gico. O objetivo deste estudo foi atrav?s de uma abordagem meta-anal?tica, entender como estes organismos afetam a decomposi??o foliar em ecossistemas aqu?ticos, e como este efeito varia de acordo com aspectos ecol?gicos e metodol?gicos. Foram inclu?dos estudos que avaliaram as taxas de decaimento exponencial na presen?a e aus?ncia de invertebrados, sendo abordadas apenas as vari?veis presentes em mais de 90% dos estudos do banco de dados. Como esperado, a presen?a dos invertebrados acelera a decomposi??o foliar e sua magnitude do efeito em escala global ? consistente. Este efeito n?o difere em rela??o ao tipo de ecossistema (l?tico ou l?ntico), temperatura ou latitude. Portanto, esta an?lise contradiz o argumento que invertebrados tem um maior papel na decomposi??o em ecossistemas de altas latitudes enquanto microrganismos deveriam ser mais importantes mais pr?ximo aos tr?picos. N?o observou-se nenhum vi?s ou quanto aos m?todos de exclus?o dos invertebrados ou ainda quanto a diferen?a entre as malhas. Apesar de ser dif?cil afirmar que n?o existem efeitos aditivos da exclus?o experimental ou ainda a diferen?a entre as malhas. Provavelmente outros par?metros n?o foram inclu?dos nesta an?lise poderiam explicar o efeito dos invertebrados na decomposi??o foliar, entretanto um insuficiente n?mero de par?metros dispon?veis dificultam mais avalia??es. Esta s?ntese conclui que o papel acelerador dos invertebrados detrit?voros deveria ser inclu?da em modelos biogeoqu?micos. Mais especificamente, estes modelos deveriam incorporar par?metros como a origem do detrito e a dura??o experimental. / There is no study aimed to synthesize the magnitude and variation of aquatic invertebrates for the decomposition of leaf litter in aquatic ecosystems. Furthermore, there is also a lack of knowledge about what is the overall impact of these small organisms on leaf decomposition. Moreover, there are a number of controversies that are the most influential factors on one of the most important processes of aquatic ecology. For example, the influence of latitude and temperature or yet the methodology employed for measuring the effect of the aquatic detritivorous invertebrates. Therefore the aim of our study was, through a meta-analytic review, understand how these organisms affect the decomposition of foliar detritus in aquatic ecosystems, and how this effect varies according to the methodological and environmental parameters most used. Through the evaluation of decomposition rates (k) in the presence and absence of these invertebrates 104 independent studies satisfied our selection criteria and were included in the database. To intention present representativeness of the sample, each used parameter in this analysis need to be present in over 90% of the selected studies. No publication bias was detected, although we verified a significant decrease in the invertebrate decomposition effect in longer experimental duration, indicating that short experiments reveal higher detritivoria while longer experiments manifest lower mass loss. As expected, these results cast reveal that in general the presence of invertebrates accelerates the decomposition process. Furthermore the global effect size, these effect are consistent and do not differ in relation to aquatic ecosystem types (lotic, lentic or marine), temperature or latitude of the experiments, even presenting a slight increase importance of invertebrates in the decomposition process toward lower latitudes. Therefore, this analysis contradicts the argument that invertebrates have a greater role in the decomposition of aquatic ecosystems at higher latitudes while microorganisms would be more important at minors. Temperature result also contradicts the preview and results of this and other reviews where it could reveal some variation of invertebrate effect. No weakness of invertebrate exclusion methods (mesh bags, electric field or toxic) or even the standardized mesh bag difference (a standardized difference between coarse and fine mesh bags) was found. In contrast to the most of literature, these parameters did not show any significant relationship with the effect size. However should be difficult affirm there is no additive effects of experimental exclusion or also standardized mesh size difference. Conversely, other factors interfere significantly in the decomposition mediated by invertebrates such as detritus origin (allochthonous or autochthonous) and experimental duration. Probably other parameters besides the not included in this analysis could explain the effect of invertebrates on leaf decomposition, however an insufficient number of available parameters hamper this assay. We conclude that this synthesis indicates that the role of detritivorous invertebrates should be included in biogeochemical models, which consider nutrient cycling in temperate or tropical aquatic ecosystems. More specifically these models should incorporate environmental parameters such as detritus origin, as well methodological parameters such as experimental duration.

Submitted by PPG Medicina e Ci?ncias da Sa?de (medicina-pg@pucrs.br) on 2018-10-10T18:14:57Z No. of bitstreams: 1 Dissera??o CRIS rev_VFinal.pdf: 2998966 bytes, checksum: fef2ba937c2e3faa8a245d6da4b908ae (MD5) / Rejected by Caroline Xavier (caroline.xavier@pucrs.br), reason: Devolvido devido ? data de defesa cadastrada na publica??o (27/07/2018) estar diferente da data de defesa que consta na folha de aprova??o da banca (28/06/2018) no arquivo PDF. on 2018-10-16T17:23:19Z (GMT) / Submitted by PPG Medicina e Ci?ncias da Sa?de (medicina-pg@pucrs.br) on 2018-10-17T18:39:08Z No. of bitstreams: 1 Dissertac?a?o_Cristina_Sebastiao_Matushita rev_VFinal_corrigida.pdf: 2373644 bytes, checksum: 8a866e5c464e92b65ce80b925e027963 (MD5) / Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2018-10-19T11:20:18Z (GMT) No. of bitstreams: 1 Dissertac?a?o_Cristina_Sebastiao_Matushita rev_VFinal_corrigida.pdf: 2373644 bytes, checksum: 8a866e5c464e92b65ce80b925e027963 (MD5) / Made available in DSpace on 2018-10-19T11:26:52Z (GMT). No. of bitstreams: 1 Dissertac?a?o_Cristina_Sebastiao_Matushita rev_VFinal_corrigida.pdf: 2373644 bytes, checksum: 8a866e5c464e92b65ce80b925e027963 (MD5) Previous issue date: 2018-06-27 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The purpose of this study was to assess the diagnostic performance of 68Ga?Prostate-specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) for detection of prostate cancer and recurrent prostate cancer. Methods: A systematic search was performed in PubMed, Cochrane and Embase to identify relevant published studies reporting on the performance of 68Ga?Prostate-specific Membrane Antigen (PSMA) PET in patients with suspected, confirmed, untreated or recurrent Prostate Cancer. A composite standard included changing in PSA values, clinical follow?up and histopathological findings as reference standard. Results: Thirty-five studies including in total 3532 patients who underwent a 68Ga-PSMA PET met our inclusion criteria. We obtained a pooled positive likelihood ratio (LR) of 1.81 (0.75 to 4.36) with 0% heterogeneity. For patients with PSA <0.5ng/mL, the positive LR pooled estimate was 1.17 (0.37-3.73) and the sensitivity was 56% (0.42-0.68). Conclusion: This meta-analysis of available studies demonstrates that 68Ga-PSMA PET appears to provide good sensitivity and specificity. / O objetivo deste estudo foi avaliar o desempenho diagn?stico da tomografia por emiss?o de p?sitrons (PET) com ant?geno de membrana espec?fico da Pr?stata (PSMA) para detec??o de c?ncer de pr?stata e c?ncer de pr?stata recorrente. M?todos: uma pesquisa sistem?tica foi realizada em PubMed, Cochrane e Embase para identificar estudos relevantes publicados que relatam o desempenho do PSMA PET marcado com 68Ga em pacientes com c?ncer de pr?stata suspeito, confirmado, n?o tratado ou recorrente. Um composto padronizado incluiu altera??o nos valores de PSA, acompanhamento cl?nico e achados histopatol?gicos como padr?o de refer?ncia. Resultados: trinta e cinco estudos, que inclu?ram no total 3532 pacientes submetidos a um PET de 68Ga-PSMA, atendiam aos crit?rios de inclus?o. Obtivemos uma raz?o de verossimilhan?a positiva combinada (LR) de 1,81 (0,75 a 4,36) com 0% de heterogeneidade. Para pacientes com PSA <0,5ng/mL, a estimativa de LR combinada positiva foi de 1,17 (0,37-3,73) e a sensibilidade foi de 56% (0,42-0,68). Conclus?o: Esta meta-an?lise de estudos dispon?veis demonstra que o PET de 68Ga-PSMA parece fornecer boa sensibilidade e especificidade.