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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
51

The Effect of Zoledronate Pretreatment on BMP Induced Bone Formation in Mice

Prichert, Marina 19 December 2011 (has links)
Recombinant human bone morphogenetic proteins (rhBMPs) are increasingly used for reconstructing bony defects, fracture non-unions, and augmenting existing bone volumes. For the numerous patients taking bisphosphonates, the impact of prior bisphosphonate treatment on rhBMP bone induction is not well understood. Objective: to evaluate the effect of the prior treatment with zoledronate on rhBMP induced bone formation in mice. Methods: 42 mice were pre-treated with 0, 2, and 20 µg of zoledronate/mouse. The osteoinductive activity of a bioimplant, containing rhBMP-2, was assessed using the mouse muscle pouch assay, and analyzed with micro CT and histology. Results: micro CT demonstrated that BMP bioimplants placed in mice pretreated with 20 µg of zoledronate, formed bony ossicles of greater volume but reduced bone density compared to controls. Histologically, the heterotopic ossicles from the 20 µg group consisted of more immature bone than those from the other groups. Conclusion: bone induced by rhBMP-2 in mice pre-treated with a high concentration of zoledronate was immature as evidenced by radiographic and histologic appearance.
52

A role for bone morphogenetic protein 8b in brown adipose tissue thermogenesis and energy homeostasis

Whittle, Andrew John January 2011 (has links)
No description available.
53

Role of bone morphogenetic proteins for catecholaminergic neurons in vivo : use of the tyrosine hydroxylase locus for cell-specific inactivation of signal transduction /

Usoskin, Dmitry, January 2004 (has links)
Diss. (sammanfattning) Uppsala : Univ., 2004. / Härtill 4 uppsatser.
54

Molecular characterization of experimental traumatic brain injury /

Israelsson, Charlotte, January 2006 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 4 uppsatser.
55

BMP signaling and tenascin-C in vascular development and remodeling /

Bressan, Michael C. January 2009 (has links)
Thesis (Ph. D.)--Cornell University, January, 2009. / Vita. Includes bibliographical references (leaves 149-179)
56

Bone morphogenetic proteins (BMPS) mediate cellular response and regulate neural stem cell differentiation after acute spinal cord injury in the adult mice

Xiao, Qi, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 113-135) Also available in print.
57

Bone morphogenetic proteins (BMPS) mediate cellular response and regulate neural stem cell differentiation after acute spinal cord injury in the adult mice /

Xiao, Qi, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 113-135) Also available online.
58

Endothelial bone morphogenic protein 4 and bone morphogenic protein receptor II expression in inflammation and atherosclerosis

Song, Hannah. January 2007 (has links)
Thesis (M. S.)--Biomedical Engineering, Georgia Institute of Technology, 2008. / Committee Chair: Hanjoong Jo; Committee Member: Ajit P. Yoganathan; Committee Member: Andrew P. Kowalczyk; Committee Member: David G. Harrison; Committee Member: Kathy K. Griendling
59

The role of sonic hedgehog and bone morphogenetic proteins in the development of the vertebrate midbrain

Fogel, Jennifer Lynn, January 1900 (has links)
Thesis (Ph. D.)--University of Texas at Austin, 2008. / Vita. Includes bibliographical references.
60

Intercellular Signaling Pathways in the Initiation of Mammalian Forebrain Development

Yang, Yu-Ping, January 2007 (has links)
Thesis (Ph. D.)--Duke University, 2007. / Includes bibliographical references.

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