Objectives: The aim of this study was to determine if exposure to volatile organic compounds can lead to DNA damage and impaired DNA repair capacity. Nail cosmetics is a fast growing industry around the world where employees and clients are subjected to various chemical substances which may be harmful to their health: such as formaldehyde, toluene, acetone, xylene, ethylmethacrylate, methylmethacrylate and n–buthyl acetate. These chemicals have the potential to be harmful to their health and exposure to these chemicals should be actively controlled. Formaldehyde is classified as a human carcinogen by the IARC, whereas, toluene and xylene are group three carcinogens, classified in 1999 (not classified as carcinogenic to humans), and various studies have linked DNA damage and impaired DNA repair to the above mentioned substances. Methods: Fifteen nail technicians were monitored by means of personal air sampling, measuring formaldehyde, toluene, xylene, acetone and ethylmethacrylate exposure. Fifteen unexposed subjects were chosen and matched for age and smoking habits with the exposed group. Heparinised blood samples were obtained from each test subject with which the Comet Assay was performed on lymphocytes to determine DNA damage and repair ability. Results: Exposure to ethylmethacrylates and methylmethacrylates leads to DNA damage. Methylmethacrylate causes DNA damage by specifically targeting pyrimidine (fpg) bases. N–buthyl acetate, xylene and acetone exposure impaired DNA repair capacity. The exposed group showed signs of Class III and Class IV DNA damage, whereas the control group had little Class III damage and no indication of Class IV damage. The overall DNA repair ability of the nail technicians was slightly impaired when compared to that of the control group, which is in concurrence with previous studies. Smoking habits and age did not show significant influences on the level of DNA damage and repair when compared with the control group. Conclusion: Exposure to volatile organic compounds such as ethylmethacryale and methylmethacrylate may lead to DNA damage and altered DNA repair in some individuals, although further studies are recommended. / Thesis (M.Sc. (Occupational Hygiene))--North-West University, Potchefstroom Campus, 2011.

This thesis solves design of timber structure of mountain hotel in Beskydy. The hotel is two-storey building with residential attic and no cellar. The ground plan of the building is about 15x26 m and height of the building is 14,76 m. The type of roof timbers was chosen from two options. There was used structural timber of the strength class C24, glued laminated timber of the strength class GL24 and steel S235. Program Scia Engineer was used for the static analysis of the structure. There was made only linear calculation.

This diploma thesis deals with the numerical modeling of the nail joint of the timber roof structure and it is based on the already realized physical experiment. Totally twelve various solutions, where the isotropic and ortotropic characteristics of the spruce timber and steel components change, have been created. The final values of the joint shift obtained by using of the numerical modeling are compared with results of physical experiment. Program system ANSYS is used.

The subject of this thesis was to develop project documentation for building construction. It is a new four-storey house with restaurant, situated on the outskirts of the village Bridges at Jablunkova. The building is brick, has a two-level gable and shed roof, consisting of wood roof system. Slope of the parcel on which the house is located, allows the building of the plant into the ground. Because of this it is possible to enter it, either the main entrance to the first floor or building around and over the summer terrace come directly to the restaurant on the second floor. Above it are two more floors for hotel guests only, a total of 10 accommodation units with its own bathroom.

In my thesis I will deal with the draft project documentation for sport hotel. This object is located in the quiet southeastern part of Frydlant with city views and easy access to the nearby sports facilities. It is an object of part two storey and a basement. The building is set into the sloping terrain, so the underground floor extends on to the ground. The building is based on foundation walls and footings that are made of reinforced concrete. Load-bearing walls of the underground floors are designed as reinforced concrete. Ceiling structure of the building is made as reinforced concrete beam ceiling and in other structure parts as a crosswise reinforced concrete plate. Perimeter bearing walls and two floors, are designed from the acoustic sand-lime bricks Silk. External walls are warmed by a contact insulation system. Flat single shell roof was chosen over part of the restaurant. Double-layer roof with a supporting truss structures above the main part of the building. The building is divided into functional parts. Accommodation capacities are mostly on the second floor. On the ground floor there is a restaurant with a kitchen and space for staff. In the basement there is a functional part of the wellness and gym with common dressing rooms. The only entrance path allows convenient control of customers. The building is wheelchair accessible.

This master's thesis focuses on the utilization of an artificially created weak magnetic field for navigation in 3D space. The theoretical part of this work deals with the general properties of the magnetic field and with its description. The next section of the theoretical part contains an overview of measuring principles for magnetic field measurements. Based on various types of measuring principles, the thesis elaborates on commercially available miniature sensors for magnetic field measurement with a measuring range up to 10 mT. The work focuses mainly on the magnetoresistive principle and fluxgate sensors. Furthermore, the theoretical part contains descriptions of methods for modeling the magnetic field of simple permanent magnets and various magnet assemblies. Lastly, the theoretical part involves a patent search of devices used for locating magnets that are installed in an intramedullary nail, which is used in intramedullary stabilization used on fractures of human bones. By locating the magnet in the nail, it is possible to precisely determine the position of the mounting holes. The practical part of the thesis deals with the analysis of magnetic field behavior in the vicinity of various magnetic assemblies, which were modeled in COMSOL Multiphysics using the finite element method. The models were created with the aim of analysing the behaviour of the magnetic field in the vicinity of the magnets and at the same time to find possible analytical functions that could be used to determine the position of the magnet in space relative to the probe. The result of this work is an analysis of various assemblies, which contains graphs of different dependencies and prescription of polynomial functions that approximate these dependencies. Another part of the thesis is the design of a probe that serves to locate the magnetic target. The work describes two possible methods of localization. For the differential method, a user interface in LabVIEW was created. The probe based on this method is fully capable of locating the magnet in the 2D plane. The state space search method is described only in theory.

This master´s thesis solves the constructive - technological project of pavilion of mountain hotel. It is an extension of pool hall. The master´s thesis includes: nail shoring walls, jet grouting, excavation, reinforced concrete base pan. There are technological solutions, especially prescription nail walls and jet grouting. Solution also contains the site facilities, the schedule, the situation with the solution structure of transport routes, itemized budget, proposed mechanical assembly, safety and health at work.

The master thesis covers several issues linked to a substitution of headlamp screw fixation by a plastic nail. The thesis includes an analysis of the headlamp technology, including description of the prescribed durability tests. On the basis of the analysis some new designs of plastic nails are proposed, consistent with characteristics of plastic materials. Selected outcomes of the analysis have been tested as prototypes and verified with Finite Elements Method in SimDesigner including 3D modeling capabilities provided by the Catia V5. The feasibility study regarding a casting form of the new design of plastic nails and technical economic valuation for contingent assembly mounting is included in the thesis.

<p>This work focuses on the collection and analysis of Lithium-ion battery operational and temperature data during nail penetration testing through two different experimental approaches. Raman spectroscopy, machine learning, and internal temperature sensors are used to collect and analyze data to further investigate the effects on cell operation during and after nail penetrations, and the feasibility of using this data to predict future performance.</p> <p><br></p> <p>The first section of this work analyzes the effects on continued operation of a small Lithium-ion prismatic cell after nail penetration. Raman spectroscopy is used to examine the effects on the anode and cathode materials of cells that are cycled for different amounts of time after a nail puncture. Incremental capacity analysis is then used to corroborate the findings from the Raman analysis. The study finds that the operational capacity and lifetime of cells is greatly reduced due to the accelerated degradation caused by loss of material, uneven current distribution, and exposure to atmosphere. This leads into the study of using the magnitude and corresponding voltage of incremental capacity peaks after nail puncture to forecast the operation of damaged cells. A Gaussian process regression is used to predict discharge capacity of different cells that experience the same type of nail puncture. The results from this study show that the method is capable of making accurate predictions of cell discharge capacity even with the higher rate of variance in operation after nail puncture, showing the method of prediction has the potential to be implemented in devices such as battery management systems.</p> <p><br></p> <p>The second section of this work proposes a method of inserting temperature sensors into commercially-available cylindrical cells to directly obtain internal temperature readings. Characterization tests are used to determine the effect on the operability of the modified cells after the sensors are inserted, and lifetime cycle testing is implemented to determine the long-term effects on cell performance. The results show the sensor insertion causes a small reduction in operational performance, and lifetime cycle testing shows the cells can operate near their optimal output for approximately 100-150 cycles. Modified cells are then used to monitor internal temperatures during nail penetration tests and how the amount of aging affects the temperature response. The results show that more aging in a cell causes higher temperatures during nail puncture, as well as a larger difference between internal and external temperatures, due mostly to the larger contribution of Joule heating caused by increased internal resistance.</p>

The theme of the master´s theses is to design a wooden structure of city theater with internal steel construction. The concept of wooden structure is developed in two versions according to standard ČSN EN. The theses solve the static effect of the construction and design of individual parts and materials. Theater has dimensions 49.0 x 25.6 m, max. height of 12.5 meters. The construstion is devise to withstand a weight and applicability. The supporting structure of the roof is solved using by 13 arched plate girders. The second variant is designed as arched truss girders. The gable wall is glassed-in, glass envelopes support by wooden structure with columns and side runners. The work also includes solutions for joins and construction details. The structure was solved in the program RSTAB Dlubal 8. The assessment of the components was done using additional module TIMBER Pro. First Variant of plate girder was checking by manual report. The work includes drawings.