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Tumor progression in melanocytic lesions : biological and diagnostic implications /Kanter-Lewensohn, Lena, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 6 uppsatser.
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Telomerase activity and its regulation in malignant hematopoietic cells /Xu, Dawei, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.
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Investigation of the mechanism of enhancement of invasion and tumour growth by tissue factor in human cancerTaniguchi, Tadaaki January 1999 (has links)
No description available.
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Mechanisms of invasiveness of tumours: ultrastructure of the interactions between neoplastic and normal cells in culture.January 1988 (has links)
Cheung Suet Ling. / Thesis (M.Ph.)--Chinese University of Hong Kong. / Bibliography: leaves 110-135.
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Gene expression in carcinogenesis /Fischer, Heléne, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2001. / Härtill 5 uppsatser.
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The effect of neoplastic transformation and cholesterol enrichment on the morphology, metabolism, and bioenergetics of mitochondriaDietzen, Dennis J. January 1992 (has links)
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The in vitro effects of calix[4]arene DCU1002AHodgson, Sarah Marguerite January 1999 (has links)
No description available.
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T-DNA organization in octopine crown gall tumors /Kwok, William Wai-hung. January 1983 (has links)
Thesis (Ph. D.)--University of Washington, 1983. / Vita. Bibliography: leaves [118]-133.
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Molecular genetic studies of human thyroid tumors /Frisk, Tony, January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2001. / Härtill 5 uppsatser.
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Traditional and new markers of infection in adult cancer patients and the possible interfering effect of underlying malignancy on these markersKallio, R. (Raija) 15 December 2000 (has links)
Abstract
The purpose of the present study was to compare the procalcitonin (PCT),
neopterin, interleukin-8 (IL-8), interleukin-10 (IL-10) and
interleukin-12 (IL-12) levels with those of erythrocyte sedimentation rate (ESR)
and C-reactive protein (CRP) in cancer patients with (56) and
without infection (36) and to evaluate their ability to differentiate
infections from neoplastic fever (n = 10).
The infection group had statistically higher levels of CRP
(91 vs. 19 mg/l, p < 0.001), PCT (0.28 vs.0.12 ng/ml, p < 0.001), neopterin
(12.8 pg/mL vs. 4.0 pg/mL, p < 0.001), IL-8 (27.7 vs. 16.9 pg/ml, p = 0.032),
IL-10 (3.8 pg/mL vs. 1.8 pg/mL, p = 0.005) and ratios of neopterin to
IL-12 (1.74 vs. 0.11, p < 0.001), and IL-10 to IL-12
(0.4 vs. 0.05, p < 0.001) than the non-infection group. After a subdivision
of the study population into patients with local or advanced disease,
the differences between the study groups remained statistically significant for CRP
and neopterin both in local (p < 0.05 and p < 0.001) and advanced diasease
(p < 0.01 and p < 0.001) and in advanced disease for PCT
(p < 0.001), IL-10 (p < 0.05), IL-12 (p < 0.05), neopterin to IL-12 ratio
(p < 0.01) and IL-10 to IL-12 ratio (p < 0.01). The ESR levels did not differ
between the study group (50 vs. 42 p = 0.16), while the IL-12 values were lower
in the infection group (10.6 pg/mL vs. 71.6 pg/mL, p = 0.007). The tumor load did
not influence any of the studied infection markers within the study groups.
For identifying bacteremia by area under the operating characteristics
curves (AUC), the highest values were obtained for PCT (0.92) and
neopterin (0.90), and slightly lower values were recorded for the ratios
neopterin to IL-12 (0.79) and IL-10 to IL-12 (0.75). None of the
markers or ratios were good for differentiating non-bacteremic infections
from neoplastic fever, the AUC values rangin from 0.27 for ESR to
0.61 for IL-10 to IL-12 ratio. The simultaneous use of the ratio of
neopterin to IL-12 with its high sensitivity (82%) and that of IL-10 to
IL-12 with its high specificity (90%) should be further studied.
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