Global ETD Search

11	Studying enteric nervous system development using the Sox10[delta]5 mouse mutant Law, Man-lee., 羅敏莉. January 2006 (has links) published_or_final_version / abstract / Biochemistry / Doctoral / Doctor of Philosophy Transcription factors. Autonomic nervous system. Neurogenetics.
12	Secretin: expression and neuroactive functionin the cerebellum Ng, Sai-ming, Samuel., 吳世明 January 2002 (has links) published_or_final_version / Zoology / Doctoral / Doctor of Philosophy Secretin Gene expression. Neurogenetics. Autism - Gentic aspects.
13	The pathogenesis, investigation and management of mitochondrial DNA disease Chinnery, Patrick Francis January 1999 (has links) No description available. 572.8
14	Transcripts from the head of Drosophila melanogaster Milligan, Colin D. January 1995 (has links) No description available. 572.8 Neurogenetics; Fruit fly; Nervous system
15	Behavioral and physiological effects of oxidative stress throughout the lifecycle of Drosophila sod1 mutants Woods, Scott Andrew 01 December 2017 (has links) Oxidative stress has a degenerative effect on neuronal health. Mutations in the copper zinc superoxide dismutase (SOD1), an important antioxidant, have been found in patients suffering from amyotrophic lateral sclerosis (ALS). Classical EMS induced mutations to SOD1 in Drosophila show similar loss of motor coordination and shortened lifespan seen in humans. A study of newly created human ALS point mutants along with the classic alleles show similar phenotypes in their neurodegeneration. I examined markers of oxidative stress, neuronal health and behavioral phenotypes throughout the lifecycle of aging flies. Larvae were largely found to be unaffected by mutations in SOD1, with no measured increase in ROS level over wild type (WT) flies. Mutant pupae were found to have two major defects in their circadian eclosion rhythm and their fundamental ability to eclose from the pupal casing. Adults showed the classic reduced lifespan and motor abilities. To further examine the health on non-glutamatergic synapses electroretinograms (ERGs) were recorded at different levels of survivorship indicated by Kaplan-Meier Survival curves. These ERGs show that the histaminergic synapses they record have greater degeneration in aging SOD1 mutants than in WT flies. This is true for their chronological age as well as their biological age. There was coinciding disruption of the photo transduction pathway of the photoreceptors that coincided with degeneration at the synapse. This demonstrates the separate degenerative effect of high levels of oxidative stress impart separate for the normal aging process. ALS Drosophila ERG Neurodegeneration Neurogenetics SOD Biology
16	Studying enteric nervous system development using the Sox10[delta]5 mouse mutant Law, Man-lee. January 2006 (has links) Thesis (Ph. D.)--University of Hong Kong, 2007. / Title proper from title frame. Also available in printed format.
17	Identification and analysis of novel mutants exhibiting defects in pioneer axon guidance in Caenorhabditis elegans / Sybingco, Stephanie S. January 2008 (has links) Thesis (M.Sc.)--York University, 2008. Graduate Programme in Biology. / Typescript. Includes bibliographical references (leaves 83-89). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR38831
18	Cross talk between Hox genes and sonic hedgehog signaling during mousehindbrain neurogenesis Wang, Xing'an, 王兴安 January 2010 (has links) published_or_final_version / Biochemistry / Doctoral / Doctor of Philosophy Homeobox genes. Cellular signal transduction. Neurogenetics.
19	Secretin: expression, endogenous release and multiple neuroactive actions in the cerebellum Lee, Man-yan., 李敏茵. January 2005 (has links) published_or_final_version / abstract / toc / Zoology / Doctoral / Doctor of Philosophy Secretin. Neuropeptides. Gene expression. Neurogenetics. Brain - Physiology.
20	Identification of molecular and neuroanatomical substrates regulating acute cocaine sensitvity in Drosophila melanogaster / Tsai, Linus Tzu-Yen. January 2004 (has links) Thesis (Ph.D.)--University of California, San Francisco, 2004. / Includes bibliographical references. Also available online.

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