<p>Providing carrier grade characteristics for Internet Protocol (IP) communication applications is a significant problem for IP application providers in order to offer integrated services that span IP&nbsp / and telecommunication networks. This thesis addresses the provision of life-cycle management, which is only one carrier grade characteristic, for a SoftBridge application, which is an example of IP communication applications. A SoftBridge provides semi-synchronous multi-modal IP-based communication. The work related to IP-Telecommunication integrated services and the SoftBridge is analyzed with respect to life-cycle management in a literature review. It is suggested to use an Application Server in a Next Generation Network (NGN) to provide life-cyclemanagement functionality for IP-Telecommunication applications. In this thesis, the Application Server is represented by a JAIN Service Logic Execution Environment(JSLEE), in which&nbsp / a SoftBridge application can be deployed, activated, deactivated, uninstalled and upgraded online.Two methodologies are applied in this research: exploratory prototyping, which evolves the development of a SoftBridge application, and empirical comparison, which is concerned with the empirical evaluation of a SoftBridge application in terms of carriergrade capabilities. A SoftBridge application called SIMBA&nbsp / provides a Deaf Telephony service similar to aprevious Deaf Telephony SoftBridge, However, SIMBA&rsquo / s SoftBridge design and implementation are unique to this thesis. In order to test the life-cycle&nbsp / management ability of SIMBA, an empirical evaluation is carried out including the experiments oflife-cycle management and call-processing performance. The final experimental results of the evaluation show that a JSLEE is able to provide life-cycle management for SIMBA without causing a significant decrease in performance. In conclusion, the life-cycle management can be provided&nbsp / or a SoftBridge application by using an Application Server such as a JSLEE. Futhermore, the results indicate that&nbsp / approach of using Application Server (JSLEE) integration should be&nbsp / sufficiently general to provide life cycle management, and indeed other carrier grade capabilities, for other IP communication applications. This allows IP communication applications to be&nbsp / &nbsp / &nbsp / integrated into an NGN.</p>

Understanding the genetic basis of biological processes is a fundamental component of modern ecology and evolutionary biology studies. With the recent advent of next generation sequencing (NGS) technologies, it is now possible to perform large genome and transcriptome projects for ecologically important non-model species. In this thesis, I focused on the development and application of genomic resources of two non-model bird species, the black grouse (Tetrao tetrix) and the great snipe (Gallinago media). Using the chicken genome as a reference, I developed a reference guided NGS pipeline to assemble the complete draft genome of black grouse. The draft genome has a good coverage of the main 29 chromosomes of the chicken genome. The genome was used to develop a vast number of genetic markers. Comparing this genome with that of other species, I identified the genomic regions which were important for the lineage specific evolution of black grouse. I also sequenced and characterised the spleen transcriptome of the black grouse. I identified and validated a large number of gene-based microsatellite markers from the transcriptome and identified and confirmed the expression of immune related genes. Using a similar RNA-Seq approach, I also sequenced the blood transcriptomes of 14 great snipe males with different mating success. I identified genes and single nucleotide polymorphisms (SNPs) which might be related to male mating success in this species, both in terms of gene expression levels and genetic variation structure. For the immunologically important major histocompatibility complex (MHC) gene region of black grouse, I constructed a fosmid library and used it to sequence the complete core MHC region of this species. This resource allowed me to perform a comprehensive comparative genomics analysis of the galliform MHC, by which I found that some genes in this region were affected by selective forces. I was also able to develop a single locus genotyping protocol for the duplicated MHC BLB (class IIB) genes and found that the two black grouse BLB loci followed different evolutionary trajectories. This thesis set an example of developing genomic resources in non-model species and applying them in addressing questions relevant to ecology and evolutionary biology.

Esta tesis doctoral aborda el problema de la definición de movimientos rápidos sin interrupciones (seamless handoffs) en redes heterogéneas de próxima generación (NGNs) mediante definición de un proceso de distribución de claves seguro, que habilite un proceso de re-autenticación rápida a la vez que un acceso autenticado anónimo y que no se pueda trazar. Concretamente, el sistema de control de acceso desarrollado ofrece un conjunto de características que, hasta la fecha, no han confluido en una misma solución: (1) aplicable a las futuras redes NGN basadas en EAP; (2) reducción de la latencia introducida por el proceso de autenticación en entornos móviles, con independencia del tipo de handoff realizado por el usuario; (3) que el proceso cumpla fuertes requisitos de seguridad; (4) fácil despliegue en redes existentes; (5) compatibilidad con las actuales tecnologías estandarizadas; y (6) soporte de protección de privacidad del usuario. / This PhD thesis deals with the problem of defining fast movements without interruptions (seamless handoffs) in the next generation of heterogeneous networks. This objective is achieved through a secure key distribution process, which enables a fast re-authentication process providing both user anonymity and untraceability. The developed access control system offers a set of features not covered so far by a single solution: (1) applicable for EAP-based NGNs; (2) reduction of the authentication latency in mobile environments irrespective of the type of handoff performed by the user; (3) provision of strong security properties; (4) easy deployment in current networks; (5) compatibility with current standardized technologies; and (6) user privacy support.

As a result of rapid progress in research and development, today's wireless world exhibits several heterogeneous communication networks, such as cellular networks, satellite networks, wireless local area networks (WLAN), mobile ad hoc networks (MANET), and sensor networks. These networks are complementary to each other. Hence, their integration can realize a unified wireless system that has the best features of the individual networks. This has spurred much research interest in designing integrated next-generation of wireless systems (NGWS). While existing wireless networks have been extensively studied individually, the integrated wireless system brings new challenges in architecture design, system management, and protocol design. The different wireless networks use different communication technologies and are based on different networking paradigms. Therefore, it is challenging to integrate these networks such that their heterogeneities are hidden from each other and a harmonious inter-operation among them is achieved. The objective of this research is to design a scalable, secure, and robust architecture and to develop seamless mobility management protocols for NGWS. More specifically, an architecture that integrates the heterogeneous wireless systems is first proposed for NGWS. Next, a cross-layer (Layer 2 + 3) handoff management protocol is developed for NGWS. Afterward, analytical modeling is developed to investigate the handoff performance of the existing mobility management protocols for different types of applications. Finally, a framework for multi-layer mobility management is developed to support the seamless handoff support to all types of applications in NGWS.

In response to the development of a next-generation networking (NGN) generalized multi-protocol label switching (GMPLS) technology is required for automatically switched optical network (ASON). Reconfigurable optical add-drop multiplexer (ROADM) is an indispensable device for the ASON, and the dense wavelength division multiplexed (DWDM) signals can be transmitted through the network under the management of the network administrator to configure dynamic customer needs and the desired quality of service (QoS). The ROADM can also increase the efficiency of utilizing the existing capacity of the optical fiber lines and can reduce or waive to set up additional optical fiber lines. This thesis studies a novel ROADM based on the arrayed waveguide grating (AWG) and the fiber Bragg grating (FBG) to overcome that the current ROADM cannot process that the input signal channels is greater than the wavelengths channels of AWG. Many types of ROADMs have been proposed and realized through different optical devices. Among these, hybrid optical circulator and FBG based ROADM is more attractive because of its low crosstalk and polarization insensitivity. However, it still suffers from many component counts and high insertion losses due to the use of many circulators and a multiplexer-demultiplexer pair. In this master thesis, we focus on demonstrating a novel ROADM and evaluating its crosstalk performance. It is found that the proposed ROADM has the advantage on extending the number of wavelength signal to make the system configurable and flexible.

In 21st century, the development strategy and the management policy of Information Communication Technology (ICT) is a key issue to a nation¡¦s competitiveness. Particularly, the development of telecommunication liberalization, governance in the telecommunications regime and the relevant science and technology policies of the telecommunication industry is the most important factor for creating a leading knowledge-based economy for Information Communication Technology related industries. Looking forward to the future, the trends and developments of the convergence of telecommunication, broadcasting and internet services will drive the demand for the telecommunication and broadcasting industries to look for cost-efficient provisioning of converged multimedia services. The emerging technology of next generation network (NGN) infrastructure enables the convergence of multi-access networks to deliver the multimedia contents and application services seamlessly. Therefore, the consumers, government, and industry can obtain the benefits because of technology development and industrial cooperation. In addition, the converged broadcasting and telecommunication services as well as Fixed-Mobile Converged applications over the internets results in the needs for the improvement in network interconnectivity and service interoperability. No matter it is telecommunication, broadcasting or information, to converge as common info-communication services, such as telephony, data and multimedia will eventually run over the all IP networks. Therefore, IP Multimedia Subsystem (IMS) becomes one of the promising technologies to drive it happen. However, existing policy and regulations must cope with the changes of this development. The liberalization of broadband and communication market allows the participation of the private companies to create new investment and revenue. This research studies the possible evolution of an IP-based communication infrastructure from today's networks toward a converged next generation network and proposes an Inter-Exchange Center of Converged Network Architecture (IEXCNA), applying to VoIP service. The IEXCNA model shows more efficient in the transmission, interconnectivity and reducing implementation cost of network infrastructure. Thus the consumers are able to enjoy better quality of service and cheaper rate of use for multimedia services.

The study of variation found in DNA is fundamental in human genetic studies. Single nucleotide polymorphisms (SNPs) are simple to document because they can be captured in single DNA sequence reads. Larger structural variation including duplications, insertions, deletions, termed as copy number variation (CNV), inversions and translocations are more challenging to discover. Recent studies using microarray and sequencing technologies have demonstrated the prevalence of structural variation in humans. They can disrupt genic and regulatory sequences, be associated with disease, and fuel evolution. Therefore, it is important to identify and characterize both SNPs and structural variants to fully understand their impact. This thesis presents the analysis of structural variation in the human genome. The primary DNA sample used for my experiments is the DNA of J. Craig Venter, also termed HuRef. It was the first personal human genome sequenced. I combined computational re-analysis of sequence data with microarray-based analysis, and detected 12,178 structural variants covering 40.6 Mb that were not reported in the initial sequencing study. The results indicated that the genomes of two individuals differed 1.3% by CNV, 0.3% by inversion and 0.1% by SNP. Structural variation discovery is dependent on the strategy used. No single approach can readily capture all types of variation, and a combination of strategies is required. I analyzed the formation mechanisms of all HuRef structural variants. The results showed that the relative proportion of mutational processes changed across size range: the majority of small variants (<1kb) were associated with nonhomologous processes and microsatellite events; median size variants (<10kb) were commonly related to minisatellites and retrotransposons; and large variants were associated with nonallelic homologous recombination. Eight new breakpoint-resolved HuRef inversions were genotyped in populations to elucidate these understudied variants. I discovered that the structures of inversion could be complex, could create conjoined genes, and their frequencies could exhibit population differentiation. The data here contributes to our understanding of structural variation in humans. It shows the need to use multiple strategies to identify variants, and it emphasizes the importance to examine the full complement of variation in all biomedical studies.

<p>Providing carrier grade characteristics for Internet Protocol (IP) communication applications is a significant problem for IP application providers in order to offer integrated services that span IP&nbsp / and telecommunication networks. This thesis addresses the provision of life-cycle management, which is only one carrier grade characteristic, for a SoftBridge application, which is an example of IP communication applications. A SoftBridge provides semi-synchronous multi-modal IP-based communication. The work related to IP-Telecommunication integrated services and the SoftBridge is analyzed with respect to life-cycle management in a literature review. It is suggested to use an Application Server in a Next Generation Network (NGN) to provide life-cyclemanagement functionality for IP-Telecommunication applications. In this thesis, the Application Server is represented by a JAIN Service Logic Execution Environment(JSLEE), in which&nbsp / a SoftBridge application can be deployed, activated, deactivated, uninstalled and upgraded online.Two methodologies are applied in this research: exploratory prototyping, which evolves the development of a SoftBridge application, and empirical comparison, which is concerned with the empirical evaluation of a SoftBridge application in terms of carriergrade capabilities. A SoftBridge application called SIMBA&nbsp / provides a Deaf Telephony service similar to aprevious Deaf Telephony SoftBridge, However, SIMBA&rsquo / s SoftBridge design and implementation are unique to this thesis. In order to test the life-cycle&nbsp / management ability of SIMBA, an empirical evaluation is carried out including the experiments oflife-cycle management and call-processing performance. The final experimental results of the evaluation show that a JSLEE is able to provide life-cycle management for SIMBA without causing a significant decrease in performance. In conclusion, the life-cycle management can be provided&nbsp / or a SoftBridge application by using an Application Server such as a JSLEE. Futhermore, the results indicate that&nbsp / approach of using Application Server (JSLEE) integration should be&nbsp / sufficiently general to provide life cycle management, and indeed other carrier grade capabilities, for other IP communication applications. This allows IP communication applications to be&nbsp / &nbsp / &nbsp / integrated into an NGN.</p>

The telecommunications industry is going through a difficult phase because of profound technological changes, mainly originated by the development of the Internet. They have a major impact on the telecommunications industry as a whole and, consequently, the future deployment of new networks, platforms and services. The evolution of the Internet has a particularly strong impact on telecommunications operators (Telcos). In fact, the telecommunications industry is on the verge of major changes due to many factors, such as the gradual commoditization of connectivity, the dominance of web services companies (Webcos), the growing importance of software based solutions that introduce flexibility (compared to static system of telecom operators). This thesis develops, proposes and compares plausible future scenarios based on future solutions and approaches that will be technologically feasible and viable. Identified scenarios cover a wide range of possibilities: 1) Traditional Telco; 2) Telco as Bit Carrier; 3) Telco as Platform Provider; 4) Telco as Service Provider; 5) Telco Disappearance. For each scenario, a viable platform (from the point of view of telecom operators) is described highlighting the enabled service portfolio and its potential benefits

Fiber-deployment of future telecommunications networks ("Next Generation Access" - NGA) is currently a major challenge for sector-specific regulators as well as for investing firms. Although the future socio-economic importance of new telecommunications networks is uncontroversial, the related investment activities vary substantially in international comparison. This work intends to identify the most important determinants of previous NGA deployment using data from the EU27 member states for the years 2005 to 2010. For our analysis, we employ latest data on NGA deployment, relevant competition and regulatory indicators as well as other supply and demand side controls. Our econometric model incorporates: i) aggregated country level data; ii) structurally modeled dynamics of the deployment process which allows us to disentangle long-term and short-term effects; finally, iii) we argue that there is no endogeneity problem with respect to investment activities and regulation since we refer to regulation in preceding broadband markets. For our econometric analysis, we employ several dynamic panel data methods, such as GMM and LSDVC. Our results indicate that stricter previous broadband access regulation has a negative impact on NGA deployment. As regards the dynamics of the adjustment process, we find that there are severe adjustment costs and stickiness towards the desired long-term level of NGA infrastructure. (author's abstract) / Series: Working Papers / Research Institute for Regulatory Economics