Background: According to WHO, mental health by 2030 will be the biggest burden on healthcare in the world. People with schizophrenia live an average of 12-15 years shorter than the rest of the population in Sweden. Patients with psychosis feel that they are not taken seriously, are treated poorly, and that healthcare professionals do not listen to them when they seek medical care for somatic disorders. Purpose: The purpose of the literature study is to identify the general nurse's approach in dealing with patients with mental illness in somatic care to identify possible obstacles in the meeting between nurse and patient. Method: A literature study based on 11 scientific articles. Quantitative and qualitative articles were included. The databases used to search articles were PubMed and Cinahl. Results: Three themes appear in the result: attitudes, fear and security. Nurses have negative attitudes towards people with psychosis, they feel a fear when for patients with mental illness and they feel they do not have enough skills. Conclusion: The results show that focus is needed during education, skills development and cooperation to reduce the three barriers that the results showed, thereby reducing the fact that 95.3% of nurses experience the patients with mental illness negatively / <p>Godkännande datum: 2018-11-05</p>