Background: Previous research shows that patients in palliative care want to get back to their everyday lives before the disease and do not want to be associated with the disease. Patients fear that the pain will become unsustainable and that they will lose their own autonomy in relation with palliative care. Previous research also shows that continuity in palliative care creates a sense of security for patients. Aim: To describe nurses experiences of caring for patients in palliative care Method: Systematic literature study with a descriptive synthesis based on twelve qualitative articles Result: The analysis resulted in two themes, Longing for preparation and To be emotionally involved. The themes describe nurses’ experiences whit four subthemes.  Conclusion: The nurses' experiences show a professional and personal development and at the same time they appreciate life more. They also experienced stress and impotence for the fate of patients. It also appears that colleagues were an important part of the nurse's work situation.