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Changes of plasmin and plasminogen activators in lactation and ovulationPolitis, Ioannis D. January 1989 (has links)
The role of plasmin and plasminogen activators (PA) in bovine lactation and porcine ovulation has been examined. There is no difference in the activation pattern of plasminogen to plasmin throughout the whole range of somatic cell counts (SCC) and from third to ninth month in lactation. The ratio of (plasminogen + plasmin)/plasmin, which serves as an index of the activation process, was 7.27 during early (first and second month) and 4.23 during late lactation (tenth month) and both values are different (p $<$ 0.01) from all the other ratios throughout the whole range of SCC and from third to ninth month in lactation suggesting limited and increased activation of plasminogen to plasmin during early and late lactation, respectively. Macrophages produce but they do not secrete urokinase-PA, suggesting a minor role in influencing milk plasmin. Somatotropin administration resulted in a suppression of milk plasmin in vivo. Insulin-like growth factor-1 (IGF-1), the most likely mediator of the effects of somatotropin on the bovine mammary gland, inhibited the induction of tissue-PA (t-PA) production which is observed when mammary epithelial cells are cultured in the absence of IGF-1. Plasmin and t-PA increased while PA inhibitor-1 decreased in porcine granulosa, theca interna cells and follicular fluid just prior to the time of expected ovulation suggesting a role for plasmin in follicle rupture.
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The association between prostaglandins and the plasminogen activator/plasmin system in the porcine ovulatory process /Grant, Gerald F. January 1993 (has links)
The objectives were: (1) to determine the pre-ovulatory changes in plasminogen activator (PA) and (PA) inhibitor (PAI) activities in the porcine follicle, and, (2) to determine if changes in the PA/plasmin system associated with ovulation were prostaglandin (PG)-dependent. PA activity (change in absorbance/h/mg wet tissue weight, three gilts per treatment group) was elevated in both granulosa cells (GC) and theca interna cells (TIC) prior to human chorionic gonadotropin (hCG) administration (0.582 $ pm$ 0.171 and 0.718 $ pm$ 0.221, respectively) but returned to basal levels in these two compartments (0.023 $ pm$ 0.013 and 0.052 $ pm$ 0.024, respectively) at 29 h post-hCG. PA activity remained basal thereafter in GC but increased approximately ten-fold in the TIC (0.549 $ pm$ 0.239) at the time of ovulation (three gilts at 41 h and one of three gilts at 38 h). PAI activity did not change in TIC over the pre-ovulatory period but increased in GC as ovulation approached. PAI activity in GC peaked at 38 h (being significantly different (p $<$ 0.05) to all other times except 41 h). Although indomethacin (INDO) effectively inhibited both PG synthesis (1.1 $ pm$ 0.2 vs. 9.2 $ pm$ 0.9 ng/ml in controls) and ovulation (0 vs. 27-61% in controls), elevated PA activity (0.801 and 0.349) was detected in the TIC of two out of nine INDO-treated gilts. Levels were basal (0.074 $ pm$ 0.028) in the other gilts. These inconclusive results are believed to reflect the occurrence of ovulation earlier than predicted, in as many as 40% of control gilts, and the short duration of increased PA activity at this time. In conclusion, elevated PA activity, in GC and TIC prior to ovulation induction, may play a role in follicular development. Elevated TIC PA activity may play an important role in the ovulatory process, but is probably PG-independent.
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Endocrine correlates of fecundity in the ewe /Ralph, Meredith Margaret. January 1984 (has links) (PDF)
Thesis (Ph. D.)--University of Adelaide, 1985. / Includes bibliographical references (leaves 182-210).
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Effect of nutrition on follicle development and ovulation rate in the ewe /Viñoles Gil, Carolina, January 2003 (has links) (PDF)
Diss. (sammanfattning) Uppsala : Sveriges lantbruksuniv., 2003. / Härtill 4 uppsatser.
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Studies on the sperm reservoir of the pig oviduct : with special reference to intra-luminal fluid, hyaluronan contents and sperm capacitation /Tienthai, Paisan, January 2003 (has links) (PDF)
Diss. (sammanfattning) Uppsala : Sveriges lantbruksuniv., 2003. / Härtill 5 uppsatser.
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The roles of the plasminogen activator and matrix metalloproteinase systems in ovulation and corpus luteum formation /Bodén, Ida. January 2004 (has links)
Lic.-avh. (sammanfattning) Umeå : University. / Härtill 3 uppsatser.
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The influence of season and nutrition on oestrus and ovulation in South Australian strong-wool Merino ewes /Cutten, Ian N. January 1979 (has links) (PDF)
Thesis (M.Ag.Sc.)--University of Adelaide, Dept. of Animal Physiology, 1980. / Includes bibliographical references (leaves 193-205).
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Gonadotropin-induced ovulation, spontaneous ovulation and reproductive capacity in mice and rats the deleterious effects of steroids and the protective influence of thymus preparations /Harris, O. N. January 1973 (has links)
Thesis (Ph. D.)--University of Wisconsin, 1973. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.
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Einfluß des FeeB-Gens auf die Follikeldynamik sowie die FSH- und Östradiol-17b Blutplasmakonzentrationen bei zyklischen und frühgraviden Biiriila-Merinofleischschaf-Kreuzungstieren in Abhängigkeit von der Ovulationsrate /Pfeil, Andreas. Unknown Date (has links)
Universiẗat, Diss., 2003--Leipzig.
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The effect of sex hormones on knee functionFuller, Leslie. January 2003 (has links)
Thesis (B.S.)--University of Oregon, 2003. / Includes bibliographical references (leaves 46-53).
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