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<p dir="ltr">Infographics are increasingly used as visual communication tools for conveying health information to diverse audiences. However, research is lacking on how specific infographic design factors influence learning outcomes. This study aimed to determine the comparative effectiveness of automatically advanced (Group A) versus manually advanced (Group B) infographics for promoting breast cancer awareness and knowledge. A mixed-methods quasi-experimental pretest-posttest design was utilized. The sample comprised 42 participants for analysis. Of these, the majority, 41 persons self-reported as female, with one participant indicating their gender as 'other.' Participant ages ranged from 25 to 55 years (M = 40.5, SD = 7.62). Most participants were well-educated, with graduate degrees or other advanced education beyond a bachelor's degree. Participants were randomly assigned to either the automatically advanced infographic group (Group A) or the manually advanced infographic group (Group B). Results indicated that Group B had significantly higher scores on the knowledge post-test compared to Group A, suggesting improved recall and comprehension of key information. There were no significant differences in cognitive load ratings or viewing duration between the groups. Qualitative feedback from participants suggested that Group B's manually advanced infographic facilitated better self-pacing and absorption of content. While the study's findings provide preliminary evidence supporting the efficacy of manually advanced infographics in learning complex health information, limitations are acknowledged. The research contributes to the design of patient education materials and underscores the necessity for further investigations across varied populations and health topics to understand the impact of infographic design more comprehensively on learning and behavior.</p>