Red maple (Acer rubrum), also known as swamp, water or soft maple, is endemic to eastern and central North America and was widely used as traditional medicine by the first peoples. Commercially, its well-known products include maple syrup and high-quality lumber. The potential medicinal benefits of phenolic compounds extracted from the red maple plant, such as glucitol-core containing gallotannins, include antioxidant, and antiglycation effects as well as their importance in cosmetic applications. Plant-derived proteins and peptides are important biomolecules; however to date, there is no published data on the identification of proteins/peptides from red maple leaves. Therefore, the present study focuses on the activity guided purification of proteins from red maple leaves collected in spring and fall seasons. In addition, the focus of this project was in the evaluation of maple leaves employing bottom-up proteomics and De Novo protein profiling by PEAKS Studio-X and Gene Ontology Bioinformatics. The red maple leaves were grounded, defatted in hexane and proteins extracted in 25 mM sodium phosphate buffer pH 6.5. The extracted crude proteins were recovered by precipitation in 80% ammonium sulfate. The first-dimensional chromatography of crude extracted proteins was performed on a gel filtration column (HiLoad 16/600 Superdex200). The separation of crude extract and the partially purified gel filtration fraction was conducted by reversed-phase HPLC. The crude and eluted fractions were analyzed by SDS-PAGE gel electrophoresis. The extract was screened for cytotoxicity activity on Michigan Cancer Foundation-7 breast cancer (MCF-7), M.D. Anderson Metastasis Breast (MDA-MB-231) cancer cell lines and anti-inflammatory activity on murine macrophage (RAW 264.7) cell line from American Type Culture Collection (ATCC). The drug Doxorubicin was used as a positive control whereas untreated cells as a negative control in these experiments Preliminary data revealed that active protein fractions were eluted at two different regions of gel filtration chromatography both in spring and fall leaves. Bottom-up proteomics of crude and active fractions by PEAKS Studio-X and MASCOT bioinformatics database identified over 54 proteins. The Gene Ontology Annotation classified these proteins involved in the biological processing, cellular compartment, and molecular functions.

Current models of quality in the marketing discipline tend to have a producer orientation. Influences on quality outside the control of the firm, such as consumer perceptions or needs, are only addressed in a rudimentary manner. While quality is acknowledged as being determined by the consumer and akin to an attitude, ironically, literature on quality is not well grounded in relevant theory from psychology and related disciplines. This thesis presents an exploration of quality and its meaning within the context of assessing scholarly marketing articles. The objective of the study is to develop a new consumer- oriented model of quality to enhance understanding of the construct, enabling marketers to better influence consumers� assessment of quality. The academic marketplace involves articulate and experienced producers, channel members and consumers. An investigation of quality within the context of marketing�s scholarly articles therefore provides rich material for refining the quality construct. The first stage of the research addressed two research questions related to scholarly articles: RQ1: What intrinsic factors (article attributes) influence quality assessments? RQ2: What extrinsic factors (external to the article) influence quality assessments? The components of quality in scholarly articles were drawn from several sources: literature sources; journal editorial policies; key informant interviews; and analysis of the content and editorial boards of the top journals. Overall, results suggested a connection between consumers� assessments of quality and factors such as their belief structures, reference group norms, and consumption context. The empirical findings led to further investigation through literature analysis. Theories from psychology helped to explain the interplay of beliefs, attitudes and perceptions in quality assessments and suggest consumer characteristics (such as the rigidity of mental sets, or novelty seeking behaviour) that influence that interplay. On a theoretical level, the new quality model integrates theories of psychology with product-oriented aspects providing a multifaceted view of the quality construct. This is achieved by using the Theory of Planned Behaviour as the central framework, providing a robust depiction of quality assessment from a consumer perspective. Elements of quality from managerial models, such as product attributes and company image, are found to fit logically into the new structure. The new model also reveals connections with the philosophy and sociology of science and provides an enhanced understanding of the workings of academia and the dissemination of scholarly knowledge. There has previously been no comprehensive study of quality in academic articles, therefore on a practical level the model of quality supports authors in producing improved manuscripts, thus enabling faster review and dissemination of research within the discipline. Further research to refine and test the model is recommended.

Errata pasted onto front end paper. / Bibliography: leaves 193-211. / xiv, 211 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Describes the development and application of an in vitro model used to investigate the cytoprotective effects of a whey-derived growth factor extract in reducing epithelial cell death caused by chemotherapy agents. / Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 1998

Thesis (M. Des.)--Unitec New Zealand, 2007. / Includes bibliographical references (leaves 103-106).

Thesis (Ph. D.)--University of Hong Kong, 2006. / Title proper from title frame. Also available in printed format.

No description available.

Thesis (Ph. D.)--Oregon State University, 1972. / Typescript (photocopy). Includes bibliographical references. Also available on the World Wide Web.

Thesis (M.S.)--University of Delaware, 2006. / Principal faculty advisor: Titus O. Awokuse, Dept. of Food & Resource Economics. Includes bibliographical references.

Thesis (M.S.)--Brigham Young University. Dept. of Mechanical Engineering, 2005. / Includes bibliographical references (p. 105-106).

Thesis (Ph.D.)--York University, 2004. Graduate Programme in Chemistry. / Typescript. Includes bibliographical references (leaves 167-179). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pNQ99174