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A study of the function and structure relationship of the voltage gated skeletal muscle chloride channel, CLC-1Wu, Wei-Ping January 2003 (has links)
In the skeletal muscle cell membrane, the voltage gated chloride channel, CIC-1, maintains as unusually high resting membrane conductance and thereby prevents myotonic skeletal muscle disease. Protein crystallization experiments with bacterial CIC proteins, provide the information for the three dimensional (3D) structure of CIC chloride channels. / PhD Doctorate
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