Thesis (M.S.)--University of Michigan, Ann Arbor, 1955. / Typescript (carbon copy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 47-48).

Thesis (M.S.)--University of Michigan, 1947.

Background: Despite the high success rates reported with the use of a five minute application of formocresol it has been postulated that it may be applied for a lesser amount of time and still achieve equivalent results. Few studies have adequately addressed the effects of the medicament on permanent successors and exfoliation times. Furthermore, the effects of shorter application times on success rates have not been adequately reported. Objectives: To assess the clinical and radiographic outcomes of a one minute application of full strength Buckley’s formocresol with concurrent hemostasis using the medicated cotton pledget in human primary teeth. To evaluate the effect of this technique on their successors and to evaluate the exfoliation times in comparison to the contralateral non-pulpotomized tooth. Methods: Using a retrospective chart review, clinical and radiographic data were available for 557 primary molars in 320 patients. Descriptive statistics and regression analysis were used to assess outcomes. Results: 99.3% clinical and 89.8% radiographic success rates were obtained. Internal root resorption (4.85%) and pulp canal obliteration (1.97%) were the most frequently observed radiographic failures. Sixty-five and half percent exfoliated at the same time as their contra-lateral counterpart and 28.8% exfoliated earlier (p<0.001). There was no difference in the number of enamel defects of succedaneous teeth between treated and control teeth (p>0.05). Conclusions: Success rates for the modified technique are comparable to techniques that use the five-minute dilute or full strength solutions reported in the literature. The one minute technique had no clinical effect on exfoliation times or incidence of enamel defects on succedaneous teeth. The one minute full strength formocresol technique is an acceptable alternative to published traditional techniques.

Background: Despite the high success rates reported with the use of a five minute application of formocresol it has been postulated that it may be applied for a lesser amount of time and still achieve equivalent results. Few studies have adequately addressed the effects of the medicament on permanent successors and exfoliation times. Furthermore, the effects of shorter application times on success rates have not been adequately reported. Objectives: To assess the clinical and radiographic outcomes of a one minute application of full strength Buckley’s formocresol with concurrent hemostasis using the medicated cotton pledget in human primary teeth. To evaluate the effect of this technique on their successors and to evaluate the exfoliation times in comparison to the contralateral non-pulpotomized tooth. Methods: Using a retrospective chart review, clinical and radiographic data were available for 557 primary molars in 320 patients. Descriptive statistics and regression analysis were used to assess outcomes. Results: 99.3% clinical and 89.8% radiographic success rates were obtained. Internal root resorption (4.85%) and pulp canal obliteration (1.97%) were the most frequently observed radiographic failures. Sixty-five and half percent exfoliated at the same time as their contra-lateral counterpart and 28.8% exfoliated earlier (p<0.001). There was no difference in the number of enamel defects of succedaneous teeth between treated and control teeth (p>0.05). Conclusions: Success rates for the modified technique are comparable to techniques that use the five-minute dilute or full strength solutions reported in the literature. The one minute technique had no clinical effect on exfoliation times or incidence of enamel defects on succedaneous teeth. The one minute full strength formocresol technique is an acceptable alternative to published traditional techniques.

Thesis (M.S.)--University of Michigan, Ann Arbor, 1971. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 54-55).

Thesis--University of Lund. / Includes reprints of the author's articles. Includes bibliographical references.

Thesis (M.S.)--University of Southern California, 1998. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis (M.S.)--University of Southern California, 1998. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Orientador: Eloi Dezan Junior / Banca: Marco Antonio Hungaro Duarte / Banca: Luciano Tavares Ângelo Cintra / Banca: Rogério de Castilho Jacinto / Banca: Rodrigo Ricci Vivan / Resumo: O objetivo deste estudo foi avaliar resposta tecidual e a capacidade de mineralização dos materiais endodônticos, Biodentine®, MTA Branco Angelus®, quando comparados com hidróxido de cálcio. Quarenta e oito ratos Wistar foram utilizados; 24 para análise subcutânea e 24 foram submetidos à pulpotomia. Após 7, 15, 30 e 60 dias (subcutâneo) os animais foram eutanasiados e foi realizado o processamento histológico e imunoistoquímico (Fibronectina e Tenascina). Após 7 e 15 dias (pulpotomia) as peças foram submetidas a processamento histológico e imunoistoquímico (Fibronectina e Tenascina) para avaliação da formação da ponte de tecido duro e resposta tecidual da polpa. Os dados tanto do subcutâneo quanto das pulpotomias foram submetidos ao teste de Kruskal Wallis e Dunn (p<0,05 A análise estatística mostrou que no subcutâneo aos 15 dias o Biodentine® gerou menor resposta inflamatória que o Ionômero de vidro e o Ca(OH)2 (p<0,05) enquanto o MTA não apresentou diferença estatística. Na polpa aos 7 dias o MTA e o Hidróxido de cálcio tiveram maior continuidade da ponte de tecido duro que o Ionômero de vidro (p<0,05) e o Biodentine apresentou melhores aspectos morfológicos que o Ionômero de vidro (p<0,05). Aos 15 dias o MTA e o Biodentine apresentaram ponte de tecido duro completa (p<0,05). Para a imunomarcação não houve diferença estatística no subcutâneo, para a pulpotomia o Biodentine obteve maior imunomarcação que o Ionômero de vidro tanto para Fibronectina quanto para Tenascina. O Bi... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The aim of the study was to evaluate the tissue response and the mineralization capacity of the endodontic materials, Biodentine®, White MTA Angelus®, when compared with calcium hydroxide. Forty-eight Wistar rats were used; 24 for subcutaneous analysis and 24 underwent pulpotomy. After 7, 15, 30 and 60 days (subcutaneous) the animals were euthanized and histological and immunohistochemical processing were performed (Fibronectin and Tenascin). After 7 and 15 days (pulpotomy) the pieces were submitted to histological and immunohistochemical processing (Fibronectin and Tenascin) to evaluate the formation of the hard tissue bridge and tissue response of the pulp. Data from both subcutaneous and pulpotomy were submitted to the Kruskal Wallis and Dunn test (p<0.05). Statistical analysis showed that in the subcutaneous tissue at 15 days Biodentine® generated a lower inflammatory response than the glass ionomer and Ca(OH)2 (p<0,05),while the MTA presented no statistical difference (p>0,05). In the pulp at 7 days, the MTA and the calcium hydroxide had a higher continuity of the hard tissue bridge than the glass ionomer (p<0,05) and Biodentine presented better morphological features than the glass ionomer (p<0,05). At 15 days the MTA and Biodentine showed a complete hard tissue bridge (p<0,05); For immunostaining, there was no statistical difference in the subcutaneous tissue; for pulpotomy, Biodentine obtained higher immunostaining than the glass ionomer for both Fibronectin and Tena... (Complete abstract click electronic access below) / Doutor

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