Call number: LD2668 .T4 1955 K53 / Master of Science

No description available.

Call number: LD2668 .T4 1957 S55 / Master of Science

No description available.

No description available.

Orientador: José Luiz Laus / Banca: Duvaldo Eurides / Banca: Márcia Rita Fernandes Machado / Resumo: São diversas as indicações para o emprego de adesivos derivados do cianoacrilato na área médica. Em oftalmologia humana, há décadas, estes biomateriais são utilizados com resultados satisfatórios. Entretanto, em veterinária, ainda são escassos o conhecimento de suas propriedades e a sua aplicação. Considerando o interesse em se avaliar o comportamento do etil-cianoacrilato, comparativamente ao octil-cianoacrilato, clínica e histopatologicamente, em córneas de coelhos, empregaramse 36 animais, nos quais, após ceratectomia lemelar de 3 mm de diâmetro, os adesivos foram aplicados e recobertos por uma fina película acelular. No pós-operatório, foram realizadas avaliações gerais (dias 1 a 10), exames oftálmicos (dias 0, 1, 3, 5, 7, 10, 14, 21, 30, 44 e 60) e estudos histopatológicos (períodos 3, 7, 14, 21, 30 e 60). Consideraram-se, ainda, os custos e disponibilidade dos adesivos. Clinicamente, houve diferença significativa para as variáveis, consumo de água, atitude, blefarite, edema corneal, teste da fluoresceína e tempo de permanência dos adesivos. À histopatologia, para o etil-cianoacrilato, já nos primeiros períodos de avaliação, observou-se epitelização corneal, organização do colágeno e moderada reação inflamatória. Para o octil-cianoacrilato, constatou-se a permanência do adesivo até as fases mais tardias, sob o qual, mais lentamente os eventos de reepitelização e organização do colágeno ocorreram com reação inflamatória discreta. Os custos e disponibilidade de aquisição do etil-cianoacrilato foram mais acessíveis do que os do octil-cianoacrilato. / Abstract: There are several indications for the employment of adhesives derived from the cyanoacrylate in the medical area. In human ophthalmology, from decades, the cyanoacrylates have been used with satisfactory results. However, in veterinary medicine, there is a scarcity of knowledge of its properties and applications. Considering the objective of evaluating the behavior of the ethyl-cyanoacrylate, comparatively to octhyl-cyanoacrylate, clinically and histopatologically, in rabbit corneas, there were used 36 animals. After lamellar keratectomy with 3 mm of diameter the adhesives was applied and recovered with a fine pellicle. In the post operative period general (days 1 to 10), ophthalmic (days 0, 1, 3, 5, 7, 14, 21, 30, 44 and 60) and hystopathologic (periods 3, 7, 14, 21, 30 and 60) exams was performed. There was also considered the costs and accessibility of the adhesives. Clinically, there were significant differences for the variables water consumption, attitude, blepharitis, corneal edema, fluorescein test and adhesive permanence time. With respect to the histopathological evaluation, for the treatment with ethyl-cyanoacrylate, there was observed already in the very first periods of evaluation, corneal epitelization, collagen organization and moderate inflammatory reaction. For the octhyl-cyanoacrylate treatment, there was observed the adhesive permanence until later phases, under which more vagarously the events of reepithelization and collagen organization occurred with a discrete inflammatory reaction. The ethyl-cyanoacrylate presented minor costs and more facility to acquire. / Mestre

Made available in DSpace on 2014-06-11T19:23:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-02-23Bitstream added on 2014-06-13T20:11:25Z : No. of bitstreams: 1 barbosa_vt_me_jabo.pdf: 1455341 bytes, checksum: 765b2ab3aba98040b2ac44da5d3e3c3e (MD5) / Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) / São diversas as indicações para o emprego de adesivos derivados do cianoacrilato na área médica. Em oftalmologia humana, há décadas, estes biomateriais são utilizados com resultados satisfatórios. Entretanto, em veterinária, ainda são escassos o conhecimento de suas propriedades e a sua aplicação. Considerando o interesse em se avaliar o comportamento do etil-cianoacrilato, comparativamente ao octil-cianoacrilato, clínica e histopatologicamente, em córneas de coelhos, empregaramse 36 animais, nos quais, após ceratectomia lemelar de 3 mm de diâmetro, os adesivos foram aplicados e recobertos por uma fina película acelular. No pós-operatório, foram realizadas avaliações gerais (dias 1 a 10), exames oftálmicos (dias 0, 1, 3, 5, 7, 10, 14, 21, 30, 44 e 60) e estudos histopatológicos (períodos 3, 7, 14, 21, 30 e 60). Consideraram-se, ainda, os custos e disponibilidade dos adesivos. Clinicamente, houve diferença significativa para as variáveis, consumo de água, atitude, blefarite, edema corneal, teste da fluoresceína e tempo de permanência dos adesivos. À histopatologia, para o etil-cianoacrilato, já nos primeiros períodos de avaliação, observou-se epitelização corneal, organização do colágeno e moderada reação inflamatória. Para o octil-cianoacrilato, constatou-se a permanência do adesivo até as fases mais tardias, sob o qual, mais lentamente os eventos de reepitelização e organização do colágeno ocorreram com reação inflamatória discreta. Os custos e disponibilidade de aquisição do etil-cianoacrilato foram mais acessíveis do que os do octil-cianoacrilato. / There are several indications for the employment of adhesives derived from the cyanoacrylate in the medical area. In human ophthalmology, from decades, the cyanoacrylates have been used with satisfactory results. However, in veterinary medicine, there is a scarcity of knowledge of its properties and applications. Considering the objective of evaluating the behavior of the ethyl-cyanoacrylate, comparatively to octhyl-cyanoacrylate, clinically and histopatologically, in rabbit corneas, there were used 36 animals. After lamellar keratectomy with 3 mm of diameter the adhesives was applied and recovered with a fine pellicle. In the post operative period general (days 1 to 10), ophthalmic (days 0, 1, 3, 5, 7, 14, 21, 30, 44 and 60) and hystopathologic (periods 3, 7, 14, 21, 30 and 60) exams was performed. There was also considered the costs and accessibility of the adhesives. Clinically, there were significant differences for the variables water consumption, attitude, blepharitis, corneal edema, fluorescein test and adhesive permanence time. With respect to the histopathological evaluation, for the treatment with ethyl-cyanoacrylate, there was observed already in the very first periods of evaluation, corneal epitelization, collagen organization and moderate inflammatory reaction. For the octhyl-cyanoacrylate treatment, there was observed the adhesive permanence until later phases, under which more vagarously the events of reepithelization and collagen organization occurred with a discrete inflammatory reaction. The ethyl-cyanoacrylate presented minor costs and more facility to acquire.

The greatest advances in medicine during the last century have been in the control of infectious diseases. These successes were based fundamentally upon the discoveries of bacteriologists and others of the relation of micro-organisms to disease processes. On the other hand most of the chronic diseases such as, muscular dystrophy, arthritis, cancer and atherosclerosis have not as yet been shown to have any comparable unifying thread to connect them. [...]

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Includes bibliographical references. (p. 131-140) / 140 leaves : ill. (some col.) ; 26 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Zoology, 1968