No description available.

No description available.

No description available.

No description available.

Thesis (Ed.M.)--Boston University

Thesis (M.M.)--Boston University

This dissertation for the Doctor of Musical Arts degree in Composition consists of a fourteen-minute work for flute, clarinet, prepared piano, percussion, violin, violoncello, and four-channel electronic sounds. The work was commissioned by the Third Practice Electroacoustic Festival and Ansembel U:. The quadrophonic electronic element consists of instrumental and hydrophonic field recordings, taken in several Estonian bogs and lakes. Ansembel U first performed the piece: in St. Cloud, Minnesota on November 4, 2015 and later performed in Richmond, Virginia and Tallinn, Estonia.

Successful synaptic transmission at the neuromuscular junction depends on the precise alignment of the nerve terminals with the postsynaptic specialization of the muscle fiber. It is increasingly apparent that this precision is achieved during development and maintained in the adult through signals exchanged between motoneurons and their target muscle fibers that serve to coordinate their spatial and temporal differentiation. There is increasing evidence that retinoic acid (RA), a derivative of Vitamin A, plays important roles in the development of nervous system. Here we specifically test this notion by examining the effect of RA on synaptic activity at developing neuromuscular synapse in Xenopus cell culture using whole-cell patch clamp recording. Bath application of RA rapidly (with a 10~15 min latency) and specifically enhances the spontaneous ACh secretion and the action of ¡@RA is reversible. The synaptic potentiation induced by RA was not occluded in the presence of protein synthesis inhibitor, Anisomycin and Cycloheximide,¡@suggesting this is transcription-independent. Selective RAR

Proefschrift--Leiden. / eContent provider-neutral record in process. Description based on print version record. Bibliography: p. 91.

Transport properties of a standard compact - cassette tape system are measured and software techniques devised to configure a low - cost,direct digital recording system. Tape - velocity variation is typically ± 10% of standard speed over tape lengths of 5 µm.with occasional variations of ±40%. Static tape - skew can result due to axial movement of the tape reel when it spools.Dynamic tape skew occurs and is primarily caused by tape - edge curvature with a constant contribution due to the transport mechanism.Spectral skew components range from 0.32 Hz to 8 Hz with magnitude normally within one 10 kbit/ sec- bit cell.The pinch roller works against the friction of the tape guides to cause tape deformation.Average values of tape deformation are 0.67 µm,0.85 µm and 1.08 µm for C60,C90 and C120 tape respectively. Parallel,software encoding / decoding algorithms have been developed for several channel codes.Adaptive software methods permit track data rates up to 3.33 k bits/sec in a rnultitrack system using a simple microcomputer.For a 4 - track system,raw error rates vary from 10ˉ⁷ at 500 bits/sec/track to 10ˉ⁵ at 3.33 kbits/sec/track.Adaptive software reduces skew - induced errors by 50%.A skew - correction technique has been developed and implemented on an 8 - track system at a track data rate of 10 k bits/sec. Real - time error correction gives a theoretical corrected error rate of 10ˉ¹¹for a raw error rate of 10ˉ⁷. Multiple track errors can cause mis - correction and interleaving is advised. Software algorithms have been devised for Reed - Solomon code. With a more powerful microprocessor this code m ay be combined with the above techniques in a layered error-correction scheme. The software techniques developed may be applied to N tracks with an N - bit computer.Recording density may be increased by using thin - film,multitrack heads and a faster computer.