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Synthesis of (±)-methyl rocaglate using an unprecedented acetyl bromide mediated Nazarov reactionMoorhead, Eric J. 19 July 2012 (has links)
To date, the Nazarov cyclization of a pentadienone has not been a proven methodology towards the construction of the core of the rocaglate natural products. It has been found that this conversion can be achieved using acetylbromide in excellent yield. This represents the first time acetylbromide has been employed in this manner. This methadology provides a very effective and direct route to the core structures of this class of molecules. / text
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Synthetic studies towards the antileukaemic rocaglamideHavenhand, M. January 1986 (has links)
No description available.
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The biosynthesis of natural productsHailes, Helen Claire January 1991 (has links)
No description available.
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Synthetic approaches to rocaglamideDavey, A. E. January 1987 (has links)
No description available.
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Studies directed towards the synthesis of irroratin A and studies directed towards the synthesis of rocaglamide and silvestrolRainey, Trevor James, January 1900 (has links) (PDF)
Thesis (Ph. D.)--University of Texas at Austin, 2006. / Vita. Includes bibliographical references.
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Studies on the total synthesis of (±)-rocaglamideFreund, Wesley Allen 2009 August 1900 (has links)
The use of a Nazarov cyclization for the diastereoselective synthesis of rocaglamide was studied. Chapter 1 discusses the biological activity of the rocaglamide family of natural products and details the previous synthetic work on these compounds. Chapter 2 discusses the approaches taken in the Magnus group for the total synthesis of rocaglamide. Several approaches to the natural product were undertaken. Using a novel acid bromide induced Nazarov cyclization, construction of the C-ring of the natural product was achieved. Attempts to construct the remainder of rocaglamide were ultimately unsuccessful. / text
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Studies directed towards the synthesis of irroratin A and studies directed towards the synthesis of rocaglamide and silvestrolRainey, Trevor James 28 August 2008 (has links)
Not available / text
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The Role of Eukaryotic Translation Initiation Factor 4A1 in Breast Cancer ChemoresistanceSridharan, Sangita January 2020 (has links)
No description available.
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